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Single Umbilical Artery

Congenital abnormality where one, instead of the usual two, UMBILICAL ARTERY connects the fetus to the placenta.
Also Known As:
Two Vessel Cord; Single Umbilical Arteries; Two Vessel Cords; Umbilical Artery, Single
Networked: 72 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1. Cysts
2. Pyelectasis
3. Placental Insufficiency
4. Fetal Growth Retardation (Intrauterine Growth Retardation)
5. Echogenic Bowel

Experts

1. Miller, Suzanne L: 17 articles (10/2020 - 03/2007)
2. Jenkin, Graham: 15 articles (01/2020 - 03/2007)
3. Allison, Beth J: 10 articles (10/2020 - 06/2012)
4. Polglase, Graeme R: 9 articles (10/2020 - 02/2016)
5. Sutherland, Amy E: 9 articles (01/2020 - 01/2012)
6. Wallace, Euan M: 8 articles (11/2017 - 03/2007)
7. Malhotra, Atul: 7 articles (01/2020 - 02/2016)
8. Castillo-Melendez, Margie: 6 articles (01/2020 - 01/2017)
9. Yawno, Tamara: 6 articles (01/2020 - 06/2014)
10. Pham, Yen: 3 articles (01/2020 - 12/2018)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Single Umbilical Artery:
1. Serotonin (5 Hydroxytryptamine)IBA
2. salicylhydroxamic acid (SHAM)IBA
3. Ethanol (Ethyl Alcohol)IBA
4. sodium salt monooctadecyl ester fumaric acidIBA
5. Pregnancy-Associated Plasma Protein-A (PAPP-A)IBA
6. FibrinIBA
01/01/1989 - "The most frequent placental abnormalities detailed in cases presenting major fetal malformations with normal karyotype were: velamentous insertion of the umbilical cord, placental hypotrophy, single umbilical artery, marginal retroplacental hematoma and generalized perivillous fibrin deposition. "
02/01/2014 - "Single umbilical artery was present in 7.7% of stillbirths and 1.7% of live births, velamentous cord insertion was present in 5% of stillbirths and 1.1% of live births, diffuse terminal villous immaturity was present in 10.3% of stillbirths and 2.3% of live births, inflammation (eg, acute chorioamnionitis of placental membranes) was present in 30.4% of stillbirths and 12% of live births, vascular degenerative changes in chorionic plate were present in 55.7% of stillbirths and 0.5% of live births, retroplacental hematoma was present in 23.8% of stillbirths and 4.2% of live births, intraparenchymal thrombi was present in 19.7% of stillbirths and 13.3% of live births, parenchymal infarction was present in 10.9% of stillbirths and 4.4% of live births, fibrin deposition was present in 9.2% of stillbirths and 1.5% of live births, fetal vascular thrombi was present in 23% of stillbirths and 7% of live births, avascular villi was present in 7.6% of stillbirths and 2.0% of live births, and hydrops was present in 6.4% of stillbirths and 1.0% of live births. "
01/01/2017 - "Ten of the 15 were also associated with fetal growth abnormalities (single umbilical artery; velamentous insertion; terminal villous immaturity; retroplacental hematoma; parenchymal infarction; intraparenchymal thrombus; avascular villi; placental edema; placental weight; ratio birth weight/placental weight) while 5 of the 15 associated with stillbirth were not associated with fetal growth abnormalities (acute chorioamnionitis of placental membranes; acute chorioamionitis of chorionic plate; chorionic plate vascular degenerative changes; perivillous, intervillous fibrin, fibrinoid deposition; fetal vascular thrombi in the chorionic plate). "
7. Long Noncoding RNAIBA
8. Biomarkers (Surrogate Marker)IBA
9. Placental Lactogen (Human Placental Lactogen)IBA
10. Glucose (Dextrose)FDA LinkGeneric

Therapies and Procedures

1. Ligation
2. Cesarean Section (Caesarean Section)
3. Therapeutics
4. Sutures (Suture)
5. Prenatal Care (Care, Prenatal)