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Acute Kidney Injury (Acute Renal Failure)

Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
Also Known As:
Acute Renal Failure; Acute Kidney Failure; Acute Kidney Insufficiency; Acute Renal Injury; Acute Renal Insufficiency; Kidney Failure, Acute; Kidney Insufficiency, Acute; Renal Failure, Acute; Renal Insufficiency, Acute; Acute Kidney Failures; Acute Kidney Injuries; Acute Kidney Insufficiencies; Acute Renal Failures; Acute Renal Injuries; Acute Renal Insufficiencies; Kidney Failures, Acute; Kidney Injuries, Acute; Kidney Injury, Acute; Kidney Insufficiencies, Acute; Renal Failures, Acute; Renal Injuries, Acute; Renal Injury, Acute; Renal Insufficiencies, Acute
Networked: 32068 relevant articles (1281 outcomes, 3153 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Sepsis (Septicemia)
2. Ischemia
3. Inflammation (Inflammations)
4. Critical Illness (Critically Ill)
5. Rhabdomyolysis

Experts

1. Bellomo, Rinaldo: 218 articles (10/2022 - 01/2002)
2. Ronco, Claudio: 196 articles (01/2022 - 01/2002)
3. Kellum, John A: 173 articles (10/2022 - 01/2002)
4. Devarajan, Prasad: 120 articles (06/2022 - 12/2004)
5. Parikh, Chirag R: 118 articles (07/2022 - 07/2004)
6. Bagshaw, Sean M: 117 articles (02/2022 - 08/2004)
7. Goldstein, Stuart L: 89 articles (08/2022 - 09/2003)
8. Garg, Amit X: 85 articles (03/2022 - 12/2005)
9. Wald, Ron: 82 articles (01/2022 - 01/2006)
10. Zarbock, Alexander: 64 articles (11/2022 - 11/2006)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Acute Kidney Injury:
1. Cisplatin (Platino)FDA LinkGeneric
2. CreatinineIBA
01/01/2022 - "Acute kidney injury (AKI) at onset (AOR = 4.83, P = 0.026), high serum creatinine (SCr) at six months (AOR = 0.12, P = 0.003), no response at six months to attain complete remission (AOR = 0.05, P = 0.041) and presence of flare (AOR = 0.04, P = 0.004) were predictors poor treatment outcomes. "
10/23/2020 - "The patient achieved rapid remission of acute kidney injury after DAC withdrawal, and his serum creatinine further decreased to normal level after 6 months. "
01/01/2019 - "The authors hypothesized that African Americans would demonstrate significantly greater change, and that a significantly greater proportion would demonstrate creatinine changes consistent with acute kidney injury (AKI). "
12/01/2011 - "Patients who met acute kidney injury criteria after adjustment of creatinine for fluid balance (but not before) had a mortality rate that was significantly greater than those who did not meet acute kidney injury criteria both before and after adjustment for fluid balance (31% vs. 12%, p < .001) and those who had acute kidney injury before but not after adjustment for fluid balance (31% vs. 11%, p = .005). "
09/01/2010 - "There was a significantly greater loss of kidney function among the TDF recipients, compared with control subjects (mean difference in calculated creatinine clearance, 3.92 mL/min; 95% confidence interval [CI], 2.13-5.70 mL/min), as well as a greater risk of acute renal failure (risk difference, 0.7%; 95% CI, 0.2-1.2). "
3. Biomarkers (Surrogate Marker)IBA
4. Glycerol (Glycerine)FDA LinkGeneric
5. LipopolysaccharidesIBA
6. Proteins (Proteins, Gene)FDA Link
7. Lipocalin-2IBA
8. Gentamicins (Gentamicin)FDA LinkGeneric
9. Acetylcysteine (Siran)FDA LinkGeneric
10. AntioxidantsIBA

Therapies and Procedures

1. Therapeutics
2. Renal Dialysis (Hemodialysis)
3. Continuous Renal Replacement Therapy
4. Renal Replacement Therapy (Therapies, Renal Replacement)
5. Critical Care (Surgical Intensive Care)