Iridoid Glucosides

A subclass of iridoid compounds that include a glucoside moiety, usually found at the C-1 position.

Also Known As:

Iridoidglucosides; Secoiridoid Glucosides; Glucoside, Iridoid; Glucoside, Secoiridoid; Glucosides, Iridoid; Glucosides, Secoiridoid; Iridoid Glucoside; Iridoidglucoside; Secoiridoid Glucoside

Networked: 33 relevant articles (3 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Sachdanandam, Panchanatham: 2 articles (08/2013 - 01/2012)
2.	Shanthi, Palanivelu: 2 articles (08/2013 - 01/2012)
3.	Sundaram, Ramalingam: 2 articles (08/2013 - 01/2012)
4.	Fu, Hui: 1 article (12/2022)
5.	Zhu, Hui: 1 article (12/2022)
6.	Li, Jing: 1 article (12/2021)
7.	Liu, Aimin: 1 article (12/2021)
8.	Tu, Yuanhui: 1 article (12/2021)
9.	Wang, Qingxing: 1 article (12/2021)
10.	Zhang, Buxin: 1 article (12/2021)

Related Diseases

1.	Body Weight (Weight, Body) 01/15/2012 - "Treatment of iridoid glucoside alleviated body weight loss in diabetic rats. " 08/01/2013 - "Oral administration of iridoid glucoside at a dose of 50 mg/kg body weight per day to STZ-induced diabetic rats for a period of 30 days resulted in a significant reduction in plasma and tissue (liver and kidney) cholesterol, triglycerides, free fatty acids, and phospholipids. " 01/15/2012 - "The effects of iridoid glucoside were compared with glibenclamide Administration of iridoid glucoside (50mg/kg body weight) to diabetic rats for 30 days resulted in significant reduction in the levels of plasma glucose, glycosylated hemoglobin and increase in the levels of insulin and hemoglobin. "
2.	Sepsis (Septicemia) 05/01/2009 - "This study was conducted to investigate the efficacy of cornuside, a secoiridoid glucoside compound, in cultured macrophages as well as in an experimental model of sepsis induced by cecal ligation and puncture (CLP) in rats. "
3.	Neoplasms (Cancer) 11/01/1991 - "Production of anti-tumor-promoting iridoid glucosides in Genipa americana and its cell cultures." 01/01/2014 - "Furthermore, we have isolated major iridoid glucosides from the dried flowers of I. emodi followed by the comparative cytotoxicity studies of these iridoids against five different human cancer cell lines. " 07/04/2014 - "Catalpol, an iridoid glucoside extracted from the traditional Chinese herbal medicine, Rehmannia glutinosa, is reported to exert neuroprotective, anti-inflammatory, anti-tumor and anti-apoptotic effects. " 01/01/2012 - "In conclusion, iridoid glucosides are considered to show a biphasic effect on cancer cells that is both cytostatic and cytotoxic, depending on the chemical structure and the type of cancer cell." 02/01/2019 - "Catalpol, an iridoid glucoside extracted from the root of Rehmannia glutinosa, can produce anti-inflammatory, anti-oxidant, anti-tumor, and dopaminergic neurons protecting effects. "
4.	Neuroblastoma 01/01/2023 - "The purpose of this research was to study whether verbenalin, an iridoid glucoside, and (+)-eudesmin, a furofuran lignan isolated from different plant families, can attenuate cell damage and death induced by 6-hydroxydopamine (6-OHDA) in human neuroblastoma SH-SY5Y cells. "
5.	Neuralgia (Stump Neuralgia) 12/01/2014 - "In this study, we investigated the potential of catalpol, an iridoid glucoside of Rehmannia glutinosa Steud, to alleviate neuropathic pain. "

Related Drugs and Biologics

1.	cornuside
2.	Triglycerides (Triacylglycerol)
3.	Phospholipids (Phosphatides)
4.	Insulin (Novolin)
5.	Hemoglobins (Hemoglobin)
6.	Glycated Hemoglobin (Glycosylated Hemoglobin)
7.	Glucose (Dextrose)
8.	Glyburide (Glibenclamide)
9.	Nonesterified Fatty Acids (NEFA)
10.	Cholesterol

Related Therapies and Procedures

1.	Punctures
2.	Ligation
3.	Oral Administration