HOME PRODUCTS SERVICES COMPANY CONTACT FAQ

Lemierre Syndrome

Subscribe to New Research on Lemierre Syndrome

A superinfection of the damaged oropharyngeal mucosa by FUSOBACTERIUM NECROPHORUM leading to the secondary septic THROMBOPHLEBITIS of the internal jugular vein.

Also Known As:

Lemierre Disease; Lemierre's Disease; Lemierre's Syndrome; Postanginal Sepsis; Disease, Lemierre; Disease, Lemierre's; Lemierres Disease; Lemierres Syndrome; Postanginal Sepses; Sepses, Postanginal; Sepsis, Postanginal; Syndrome, Lemierre; Syndrome, Lemierre's

Networked: 74 relevant articles (4 outcomes, 0 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Brain Abscess (Abscess, Brain)
2.	Infection
3.	Thrombosis (Thrombus)
4.	Sepsis (Septicemia)
5.	Abscess

Experts

1.	Ou, Tsong-Yih: 2 articles (04/2015 - 02/2012)
2.	Lee, Wen-Sen: 2 articles (04/2015 - 02/2012)
3.	Zafeiriou, D I: 2 articles (04/2010 - 04/2010)
4.	Vargiami, Efthimia G: 2 articles (04/2010 - 04/2010)
5.	Felipe-Silva, Aloisio: 1 article (07/2015)
6.	Rahhal, Hassan: 1 article (07/2015)
7.	de Campos, Fernando Peixoto Ferraz: 1 article (07/2015)
8.	Choi, Bo Mi: 1 article (07/2015)
9.	Park, Chan Kwon: 1 article (07/2015)
10.	Lee, Sang-Hoon: 1 article (07/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Lemierre Syndrome:

1.	Anti-Bacterial Agents (Antibiotics)IBA 09/01/1995 - "The features of Lemierre syndrome have changed little since the original description, through the prognosis has improved dramatically since the development of antibiotics. " 06/01/2012 - "The diagnosis of Lemierre's syndrome was confirmed, and he was effectively treated with appropriate antibiotics and anti-coagulation." 07/01/2015 - "Lemierre's syndrome (LS), described in detail in 1936, used to be a life-threatening entity until the advent of antibiotics. " 05/01/2015 - "Lemierre syndrome and the role of modern antibiotics and therapeutic anticoagulation in its treatment." 01/01/2015 - "With the widespread use of antibiotics, Lemierre's syndrome is rarely encountered anymore, but it can be fatal if not properly diagnosed. "
2.	Penicillins (Penicillin)FDA Link 06/01/2003 - "We present a case of Lemierre's syndrome, most notable for the patient's essentially benign physical examination and lack of clinical improvement with penicillin." 12/01/2010 - "Lemierre syndrome (LS) is considered as a forgotten disease since the beginning of Penicillin. " 04/01/2010 - "After the advent of antibiotic therapy, especially in the 1960s and 1970s, when penicillin was frequently used to treat pharyngeal infections, Lemierre syndrome was often referred to as the "forgotten disease". " 03/01/2015 - "necrophorum tonsillitis with, for example, penicillin, metronidazole, or both, we might prevent some cases of Lemierre syndrome."
3.	meropenem (Merrem)FDA LinkGeneric 01/01/2015 - "Lemierre's Syndrome Associated with Periodontal Injury-derived Odontogenic Infection that Did Not Respond to Meropenem." 02/01/2012 - "Lemierre syndrome complicating multiple brain abscesses caused by extended-spectrum β-lactamase-producing Klebsiella pneumoniae cured by fosfomycin and meropenem combination therapy."
4.	Fosfomycin FDA Link 02/01/2012 - "In individual cases of Lemierre syndrome with brain abscess caused by ESBL-producing Enterobacteriaceae, fosfomycin combination therapy may be the alternative choice." 02/01/2012 - "Lemierre syndrome complicating multiple brain abscesses caused by extended-spectrum β-lactamase-producing Klebsiella pneumoniae cured by fosfomycin and meropenem combination therapy."
5.	Carbon MonoxideIBA 10/01/2005 - "Children who were aged from birth to 21 years and had received a diagnosis of JVT and Lemierre's syndrome at the Children's Hospital (Denver, CO) between 2001 and 2005 were identified for inclusion. " 10/01/2010 - "Lemierre syndrome caused by co-infection by Arcanobacterium haemolyticum and Fusobacterium necrophorum." 11/01/2005 - "A case of Lemierre's syndrome and co-infection with Mycoplasma pneumoniae is described, association published before in only 2 other cases. " 08/01/2002 - "We report the first case of Lemierre's disease caused by a co-infection with A. " 08/01/2002 - "Lemierre's disease caused by co-infection of Arcanobacterium haemolyticum and Fusobacterium necrophorum: a case report."
6.	Methicillin (Metin)FDA Link 01/01/2008 - "One should consider the possibility of community-acquired meticillin-resistant Staphylococcus aureus infection in patients with suspected Lemierre's syndrome." 01/01/2008 - "We report a rare case of Lemierre's syndrome caused by community-acquired meticillin-resistant Staphylococcus aureus infection. " 01/01/2008 - "Lemierre's syndrome due to community-acquired meticillin-resistant Staphylococcus aureus infection and presenting with orbital cellulitis: a case report." 09/01/2012 - "The changing face of an old disease: case report of nonclassical Lemierre's syndrome caused by a Panton-Valentine leucocidin-positive methicillin-susceptible Staphylococcus aureus isolate." 01/01/2013 - "Lemierre's syndrome presenting to the ED: rapidly fatal sepsis caused by methicillin-susceptible Staphylococcus aureus Staphylococcus protein A type t044."
7.	Metronidazole (Metric)FDA LinkGeneric 10/01/2009 - "The case history is described of a middle-aged man with Lemierre's syndrome who made an uneventful recovery following treatment with co-amoxiclav and metronidazole for 6 weeks." 03/01/2015 - "necrophorum tonsillitis with, for example, penicillin, metronidazole, or both, we might prevent some cases of Lemierre syndrome." 03/01/2009 - "The patient was diagnosed with Lemierre's syndrome, and an alternative treatment regimen with prolonged administration of ampicillin, clindamycin, and metronidazole resulted in improvement of the patient's respiratory function and general condition. "
8.	Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA 08/01/2014 - "Lemierre's syndrome with double heterozygote status in the methylenetetrahydrofolate reductase gene."
9.	Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)FDA Link 10/01/2009 - "The case history is described of a middle-aged man with Lemierre's syndrome who made an uneventful recovery following treatment with co-amoxiclav and metronidazole for 6 weeks."
10.	Enoxaparin (Lovenox)FDA LinkGeneric 12/01/2012 - "A previously healthy 5-year-old male admitted with left internal jugular vein thrombosis associated with Lemierre's syndrome was placed on appropriate antibiotics and anticoagulation therapy with enoxaparin. "

Therapies and Procedures

1.	Catheters 10/01/2004 - "Cuffed-catheter-related Lemierre syndrome." 07/01/2005 - "A potential source or underlying condition that predisposed to SPE was identified in all 14 patients and included Lemierre syndrome (4 patients), central venous catheter infection (3 patients), prosthetic cardiac valve (2 patients), and pacemaker infection (2 patients). "
2.	Tonsillectomy 03/01/2004 - "Lemierre syndrome is a rare condition which may also follow tonsillectomy. " 03/01/2004 - "[Lemierre syndrome: thrombosis of the internal jugular vein after tonsillectomy]." 11/01/1997 - "Lemierre syndrome, usually seen after an oropharyngeal infection, can also complicate tonsillectomy." 11/01/1997 - "Septic arthritis of the hip by Fusobacterium necrophorum after tonsillectomy: a form of Lemierre syndrome?"
3.	Critical Care 11/01/2003 - "Critical care nurses be aware: Lemierre's syndrome is on the rise." 01/01/2003 - "In a retrospective study conducted between 1995 and 2000 in two departments (infectious diseases and critical care unit) of Nice university hospital (Nice, France), we collected and analysed six cases of Lemierre's syndrome. "
4.	Laryngoscopes 04/01/2010 - "Lemierre syndrome, also known as postanginal sepsis, is a severe complication of an acute oropharyngeal infection that results in septic thrombophlebitis of the ipsilateral internal jugular vein with subsequent septicemia, often complicated by metastatic infections (Syed et al., Laryngoscope 117:1605-1610, 2007). "
5.	Salvage Therapy 06/01/2011 - "[Use of ECMO as a salvage therapy for refractory hypoxia secondary to a Lemierre's syndrome]."