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Frontotemporal Dementia (Semantic Dementia)

The most common clinical form of FRONTOTEMPORAL LOBAR DEGENERATION, this dementia presents with personality and behavioral changes often associated with disinhibition, apathy, and lack of insight.
Also Known As:
Semantic Dementia; Dementia, Semantic; DDPAC; Dementia, Frontotemporal; Dementia, Frontotemporal, with Parkinsonism; Dementia, Hereditary Dysphasic Disinhibition; Disinhibition-Dementia-Parkinsonism-Amyotrophy Complex; Disinhibition-Dementia-Parkinsonism-Amytrophy Complex; FTD-GRN; FTD-PGRN; FTDP-17; FTLD with TDP-43 Pathology; FTLD-17 GRN; FTLD-TDP; Familial Pick's Disease; Frontotemporal Dementia with Parkinsonism; Frontotemporal Dementia with Parkinsonism-17; Frontotemporal Dementia, Ubiquitin-Positive; Frontotemporal Lobar Degeneration With Ubiquitin-Positive Inclusions; Frontotemporal Lobe Dementia; Frontotemporal Lobe Dementia (FLDEM); GRN-Related Frontotemporal Dementia; HDDD1; HDDD2; Hereditary Dysphasic Disinhibition Dementia; Multiple System Tauopathy with Presenile Dementia; Wilhelmsen-Lynch Disease; Complex, Disinhibition-Dementia-Parkinsonism-Amyotrophy; Complex, Disinhibition-Dementia-Parkinsonism-Amytrophy; Complices, Disinhibition-Dementia-Parkinsonism-Amyotrophy; Complices, Disinhibition-Dementia-Parkinsonism-Amytrophy; Dementia, Frontotemporal Lobe; Dementia, Frontotemporal Lobe (FLDEM); Dementia, GRN-Related Frontotemporal; Dementia, Ubiquitin-Positive Frontotemporal; Dementias, Frontotemporal; Dementias, Frontotemporal Lobe; Dementias, Frontotemporal Lobe (FLDEM); Dementias, GRN-Related Frontotemporal; Dementias, Semantic; Dementias, Ubiquitin-Positive Frontotemporal; Disease, Familial Pick's; Disease, Wilhelmsen-Lynch; Diseases, Familial Pick's; Diseases, Wilhelmsen-Lynch; Disinhibition Dementia Parkinsonism Amyotrophy Complex; Disinhibition Dementia Parkinsonism Amytrophy Complex; Disinhibition-Dementia-Parkinsonism-Amyotrophy Complices; Disinhibition-Dementia-Parkinsonism-Amytrophy Complices; FTLD with TDP 43 Pathology; Familial Pick Disease; Familial Pick's Diseases; Familial Picks Disease; Frontotemporal Dementia with Parkinsonism 17; Frontotemporal Dementia, GRN-Related; Frontotemporal Dementia, Ubiquitin Positive; Frontotemporal Dementias; Frontotemporal Dementias, GRN-Related; Frontotemporal Dementias, Ubiquitin-Positive; Frontotemporal Lobar Degeneration With Ubiquitin Positive Inclusions; Frontotemporal Lobe Dementias; Frontotemporal Lobe Dementias (FLDEM); GRN Related Frontotemporal Dementia; GRN-Related Frontotemporal Dementias; Lobe Dementia, Frontotemporal; Lobe Dementias, Frontotemporal; Pick's Disease, Familial; Pick's Diseases, Familial; Semantic Dementias; Ubiquitin-Positive Frontotemporal Dementia; Ubiquitin-Positive Frontotemporal Dementias; Wilhelmsen Lynch Disease; Wilhelmsen-Lynch Diseases
Networked: 2707 relevant articles (37 outcomes, 206 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Alzheimer Disease (Alzheimer's Disease)
2. Dementia (Dementias)
3. Parkinson Disease (Parkinson's Disease)
4. Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
5. Neurodegenerative Diseases (Neurodegenerative Disease)

Experts

1. Rademakers, Rosa: 75 articles (01/2022 - 05/2004)
2. Dickson, Dennis W: 73 articles (02/2022 - 10/2003)
3. Trojanowski, John Q: 72 articles (01/2022 - 05/2003)
4. Miller, Bruce L: 71 articles (01/2021 - 11/2003)
5. Borroni, Barbara: 65 articles (08/2022 - 09/2005)
6. Rohrer, Jonathan D: 56 articles (08/2022 - 03/2010)
7. van Swieten, John C: 47 articles (10/2022 - 08/2002)
8. Lee, Virginia M-Y: 45 articles (12/2021 - 05/2003)
9. Galimberti, Daniela: 44 articles (08/2022 - 06/2007)
10. Boeve, Bradley F: 44 articles (01/2022 - 03/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Frontotemporal Dementia:
1. Proteins (Proteins, Gene)FDA Link
2. Memantine (Namenda)FDA Link
3. Cholinesterase Inhibitors (Anticholinesterases)IBA
4. ProgranulinsIBA
5. Amyloid (Amyloid Fibrils)IBA
6. Rivastigmine (Exelon)FDA LinkGeneric
7. Yi-Gan SanIBA
8. Biomarkers (Surrogate Marker)IBA
9. DNA-Binding Proteins (DNA Binding Protein)IBA
10. Glucose (Dextrose)FDA LinkGeneric

Therapies and Procedures

1. Therapeutics
2. Immunotherapy
3. Transcranial Direct Current Stimulation
4. Telerehabilitation
5. Activities of Daily Living (ADL)