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Iridocorneal Endothelial Syndrome

A grouping of three closely linked conditions: iris nevus (or Cogan-Reese) syndrome, Chandler Syndrome, and essential (progressive) iris atrophy. The most common features of this syndrome are the movement of endothelial cells off the cornea onto the iris leading to corneal swelling, distortion of the iris, and variable degrees of distortion of the pupil. The abnormal cell movement plugs fluid outflow channels of the eye causing GLAUCOMA.
Also Known As:
Chandler Syndrome; Chandler's Syndrome; Iris Atrophy with Corneal Edema and Glaucoma; Chandlers Syndrome; Endothelial Syndrome, Iridocorneal; Iridocorneal Endothelial Syndromes; ICE Syndrome
Networked: 122 relevant articles (6 outcomes, 8 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Glaucoma
2. Blister (Bulla)
3. Low Vision (Subnormal Vision)
4. Atrophy
5. Keratoconus

Experts

1. Senthil, Sirisha: 5 articles (02/2022 - 01/2016)
2. Chaurasia, Sunita: 4 articles (02/2022 - 07/2014)
3. Mohamed, Ashik: 3 articles (02/2022 - 07/2014)
4. Rao, Aparna: 3 articles (12/2021 - 01/2018)
5. Huang, Ting: 3 articles (01/2021 - 01/2002)
6. Choudhari, Nikhil S: 2 articles (02/2022 - 01/2016)
7. Ji, Jianping: 2 articles (01/2021 - 01/2009)
8. Giubilato, Antonio: 2 articles (01/2020 - 12/2019)
9. Kolomeyer, Natasha N: 2 articles (01/2020 - 12/2019)
10. Lin, Michael M: 2 articles (01/2020 - 12/2019)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Iridocorneal Endothelial Syndrome:
1. IceIBA
2. SteroidsIBA
3. nepafenac (Nevanac)FDA Link
4. CollagenIBA
5. iridalIBA
6. Mitomycin (Mitomycin-C)FDA LinkGeneric
7. Keratins (Keratin)IBA
8. Tuberculin (PPD)IBA
9. SilverIBA
10. VimentinIBA

Therapies and Procedures

1. Corneal Transplantation (Keratoplasty)
2. Penetrating Keratoplasty
3. Glaucoma Drainage Implants
4. Percutaneous Collagen Induction
5. Corneal Cross-Linking