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Anterior Wall Myocardial Infarction

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MYOCARDIAL INFARCTION in which the anterior wall of the heart is involved. Anterior wall myocardial infarction is often caused by occlusion of the left anterior descending coronary artery. It can be categorized as anteroseptal or anterolateral wall myocardial infarction.

Also Known As:

Anterolateral Myocardial Infarctions; Anteroseptal Myocardial Infarctions; Infarction, Anterolateral Myocardial; Infarction, Anteroseptal Myocardial; Infarctions, Anterolateral Myocardial; Infarctions, Anteroseptal Myocardial; Myocardial Infarction, Anterolateral; Myocardial Infarction, Anteroseptal; Myocardial Infarctions, Anterolateral; Myocardial Infarctions, Anteroseptal; Acute Anterior Wall Myocardial Infarction; Anterolateral Myocardial Infarction; Anteroseptal Myocardial Infarction; Myocardial Infarction, Anterior Wall

Networked: 136 relevant articles (3 outcomes, 16 trials/studies)

Relationship Network

Disease Context: Research Results

Cardiovascular Diseases: 37259
- Heart Diseases: 18762
  - Myocardial Ischemia: 16513
    - Myocardial Infarction: 59124
      - Anterior Wall Myocardial Infarction: 136
- Vascular Diseases: 10289
  - Myocardial Ischemia: 16513
    - Myocardial Infarction: 59124
      - Anterior Wall Myocardial Infarction: 136

Related Diseases

1.	Coronary Aneurysm (Aneurysm, Coronary)
2.	Myocardial Infarction
3.	Heart Failure
4.	Coronary Artery Disease (Coronary Atherosclerosis)
5.	Body Weight (Weight, Body)

Experts

1.	Ishikawa, K: 3 articles (01/2001 - 03/2000)
2.	Yoshino, H: 3 articles (01/2001 - 03/2000)
3.	Agrawal, Navin: 2 articles (12/2013 - 01/2013)
4.	Toff, William D: 2 articles (04/2010 - 04/2008)
5.	Schron, Eleanor B: 2 articles (04/2010 - 04/2008)
6.	Bardy, Gust H: 2 articles (04/2010 - 04/2008)
7.	Tonkin, Andrew M: 2 articles (04/2010 - 04/2008)
8.	Mark, Daniel B: 2 articles (04/2010 - 04/2008)
9.	Johnson, George: 2 articles (04/2010 - 04/2008)
10.	Anderson, Jill: 2 articles (04/2010 - 04/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Anterior Wall Myocardial Infarction:

1.	stirocainideIBA 01/01/1984 - "The present study was undertaken to investigate the efficacy of the new antiarrhythmic compound stirocainide (2-(1-benzylidene)cycloheptenimino-oxyethyl-diisopropylamine -2-butenedionate, Th 494) in suppressing "2nd phase arrhythmias" arising from large anteroseptal myocardial infarctions using a standardized experimental canine preparation. "
2.	Tissue Plasminogen Activator (Alteplase)FDA Link 04/01/1994 - "The authors report use of intravenous (IV) tissue plasminogen activator (TPA) to treat acute anterior wall myocardial infarction in a forty-two-year-old woman during the active menstrual period. " 07/01/1991 - "A 42-year-old female with no cardiac risk factors had an acute anterolateral myocardial infarction treated with intravenous (IV) tissue plasminogen activator (t-PA). " 11/01/1988 - "Technetium-99m isonitrile myocardial perfusion imaging was employed in a patient undergoing thrombolytic therapy with recombinant tissue plasminogen activator for acute anteroseptal myocardial infarction. " 10/01/1995 - "Concurrent nitroglycerin administration reduces the efficacy of recombinant tissue-type plasminogen activator in patients with acute anterior wall myocardial infarction." 08/01/1992 - "For a patient presenting within 30 minutes after the onset of an uncomplicated acute anterior-wall myocardial infarction, 98% of respondents reported that they would prescribe a thrombolytic agent, 79% chose tissue plasminogen activator, and 21% chose streptokinase. "
3.	Nitroglycerin (Dynamite)FDA LinkGeneric 10/01/1995 - "Concurrent nitroglycerin administration reduces the efficacy of recombinant tissue-type plasminogen activator in patients with acute anterior wall myocardial infarction."
4.	glucuronyl glucosamine glycan sulfate (Vessel)IBA 08/02/1991 - "This patient developed a thrombotic occlusion of the vessel 3 days after the procedure which, despite high-dosage thrombolysis treatment, resulted in an anterior wall myocardial infarction. " 01/01/2012 - "In this study we investigate the effects of a well-defined bone marrow-derived allogeneic cell product delivered by catheter directly to the myocardium via the infarct-related vessel on global and regional measures of left ventricular (LV) function in a porcine model of anterior wall myocardial infarction. " 08/10/2010 - "In patients with anterior wall myocardial infarction by left anterior descending artery occluded abruptly, drug eluting stent decreases the rate of target vessel revascularization. " 08/01/1989 - "Although patients in the surgical group were older (59.7 +/- 10.4 years versus 54.9 +/- 10.2 years; p = 0.03), had more extensive coronary artery disease (42% three-vessel disease versus 11%; p = 0.001), and had a higher incidence of anterior wall myocardial infarction (48% versus 39%; p = 0.02), in-hospital mortality for the surgical group (6%) was similar to that in 301 patients not undergoing surgery (7%) in this trial. " 01/01/2001 - "Ninety consecutive patients with a first single-vessel anterior wall myocardial infarction (male/female ratio 75:15, mean age 60+/-9 years) underwent coronary angiography (CAG) immediately and 1 month after infarction. "
5.	Streptokinase FDA Link 01/01/2013 - "Occurrence of Guillain-Barré syndrome as an immune mediated complication after thrombolysis with streptokinase for acute anterior wall myocardial infarction: a caution to be vigilant." 01/01/2013 - "We report a 42-year-old gentleman who presented with anterior wall myocardial infarction (MI) and thrombolysed with streptokinase. " 01/01/1992 - "This was documented in four patients given streptokinase early in the course of anterior wall myocardial infarction. " 08/01/1994 - "The observed differences were more pronounced in patients with an anterior wall myocardial infarction, although patients with a nonanterior infarct location also showed a beneficial effect of primary coronary angioplasty on left ventricular function compared with streptokinase therapy. " 01/01/2013 - "We report the case of a 50-year-old man with acute anterior wall myocardial infarction who developed GBS as a manifestation of autoimmune hypersensitivity reaction to the drug 17 days after thrombolytic therapy with streptokinase. "
6.	Dobutamine FDA LinkGeneric 03/01/1997 - "This study was designed to investigate the effects of low-dose dobutamine infusion on early global and regional function of reperfused myocardium after acute anterior wall myocardial infarction (MI). " 09/18/2002 - "We sought to determine the relative accuracy of myocardial contrast echocardiography (MCE) and low-dose dobutamine echocardiography (LDDE) in predicting recovery of left ventricular (LV) function in patients with a recent anterior wall myocardial infarction (MI). " 01/01/2000 - "To clarify the clinical difference in viability of myocardium with negative and positive T waves in Q-wave anterior or anteroseptal myocardial infarction, we performed low-dose dobutamine stress echocardiography in 17 patients with negative T waves and in 13 patients with positive T waves with optimal revascularization of infarct-related arteries in the chronic phase of infarction. " 06/01/1998 - "A 66-year old male suffered an acute anterior wall myocardial infarction during dobutamine atropine stress echocardiography. "
7.	abciximab (ReoPro)FDA Link 03/01/2007 - "Early abciximab administration before primary percutaneous coronary intervention improves infarct-related artery patency and left ventricular function in high-risk patients with anterior wall myocardial infarction: a randomized study." 07/01/1998 - "This is the first report of a patient who presented at the emergency department with acute anterolateral myocardial infarction, in whom a single bolus injection of c7E3 Fab (0.25 mg/kg body weight) led to complete reperfusion of the infarct-related coronary artery during organization time for planned acute coronary angioplasty. "
8.	OsteopontinIBA 09/01/2003 - "The present study was designed to clarify whether osteopontin, an extracellular matrix protein, is released from the heart into the coronary circulation in patients with a previous (>3 months) anterior wall myocardial infarction (MI). " 09/01/2003 - "Osteopontin is released from the heart into the coronary circulation in patients with a previous anterior wall myocardial infarction."
9.	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 08/05/2014 - "Patients with left ventricular ejection fraction less than 45% after anterior-wall myocardial infarction were treated with G-CSF (10 μg/kg daily for 4 days) or placebo. " 08/05/2014 - "Granulocyte colony-stimulating factor therapy for stem cell mobilization following anterior wall myocardial infarction: the CAPITAL STEM MI randomized trial."
10.	Procainamide (Procan)FDA LinkGeneric 04/01/1995 - "This study evaluated the influence of infarct healing on the electrophysiologic effects of procainamide (PA) and N-acetylprocainamide (NAPA) in a sedated, closed-chest canine model with a healing anterior wall myocardial infarction, indwelling myocardial electrodes and inducible sustained ventricular tachyarrhythmias (VT). "

Therapies and Procedures

1.	Angioplasty (Angioplasty, Transluminal) 04/01/2006 - "This study involved 92 consecutive patients, hospitalised because of their first anterior wall myocardial infarction, who underwent successful (TIMI-3 grade flow) primary coronary angioplasty. " 04/01/2007 - "Thirty three patients with first anterior wall myocardial infarction underwent primary coronary angioplasty and achieved reflow within 8 hr of onset. " 01/08/2007 - "Effect of microvascular reperfusion on prognosis and left ventricular function in anterior wall myocardial infarction treated with primary angioplasty." 04/01/2006 - "Relationship between tissue reperfusion and postinfarction left ventricular remodelling in patients with anterior wall myocardial infarction treated with primary coronary angioplasty." 02/08/2006 - "Thirty patients without a known previous anterior wall myocardial infarction who underwent RA-facilitated angioplasty for de novo lesions of left anterior descending coronary artery were evaluated. "
2.	Thrombolytic Therapy 02/01/2002 - "It is suggested that an echocardiogram, if instantly available, be performed before considering thrombolytic therapy whenever acute anterior wall myocardial infarction is impressed." 11/01/2000 - "We report an unusual case of an elderly Caucasian female with an acute anterior wall myocardial infarction treated with thrombolytic therapy. " 09/01/1998 - "In patients with acute anterior wall myocardial infarction thrombolytic therapy with obtained reperfusion causes reduction of QT and QTc dispersion. " 01/01/2005 - "This study was conducted to compare the effects of reperfusion either by thrombolytic therapy or primary angioplasty on P-wave duration and dispersion in patients with acute anterior wall myocardial infarction. " 01/01/1994 - "Thrombolytic therapy was administered to a 64-year-old man with an acute anterolateral myocardial infarction who had received cardiopulmonary resuscitation (CPR) for 24 minutes. "
3.	Cardiopulmonary Resuscitation (CPR) 04/01/2010 - "The Home Automatic External Defibrillator Trial (HAT) found no survival advantage for adding a home AED to cardiopulmonary resuscitation (CPR) training for 7,001 patients with a prior anterior wall myocardial infarction. " 01/01/1994 - "Thrombolytic therapy was administered to a 64-year-old man with an acute anterolateral myocardial infarction who had received cardiopulmonary resuscitation (CPR) for 24 minutes. " 07/01/1991 - "Thrombolytic therapy was administered to a 49-year-old woman with an acute anterior wall myocardial infarction after having prolonged cardiopulmonary resuscitation for 13 minutes. " 04/24/2008 - "We randomly assigned 7001 patients with previous anterior-wall myocardial infarction who were not candidates for an implantable cardioverter-defibrillator to receive one of two responses to sudden cardiac arrest occurring at home: either the control response (calling emergency medical services and performing cardiopulmonary resuscitation [CPR]) or the use of an AED, followed by calling emergency medical services and performing CPR. "
4.	Defibrillators (Defibrillator) 04/01/2010 - "The Home Automatic External Defibrillator Trial (HAT) found no survival advantage for adding a home AED to cardiopulmonary resuscitation (CPR) training for 7,001 patients with a prior anterior wall myocardial infarction. " 04/24/2008 - "For survivors of anterior-wall myocardial infarction who were not candidates for implantation of a cardioverter-defibrillator, access to a home AED did not significantly improve overall survival, as compared with reliance on conventional resuscitation methods. " 01/01/2010 - "A 67-year-old man suffered an acute anteroseptal myocardial infarction complicated by multiple episodes of ventricular fibrillation, which were not systematically defibrillated by maximum, internal 35-J shocks delivered by an implanted cardioverter defibrillator (ICD). "
5.	Catheters 01/01/2012 - "Anterior wall myocardial infarction (AMI) was induced by 90 min of mid-LAD occlusion using a balloon catheter. " 01/01/2013 - "Four weeks after induction of an anterior wall myocardial infarction in 39 sheep, allogeneic MPCs in doses of either 25 × 10(6) (n = 10), 75 × 10(6) (n = 9), or 225 × 10(6) (n = 10) cells or nonconditioned control media (n = 10) were administered intramyocardially into infarct and border zone areas using a catheter designed for combined fluoroscopic and RT3DE-guided injections. " 01/01/2012 - "In this study we investigate the effects of a well-defined bone marrow-derived allogeneic cell product delivered by catheter directly to the myocardium via the infarct-related vessel on global and regional measures of left ventricular (LV) function in a porcine model of anterior wall myocardial infarction. "