Cyclin A1

01/01/2014 - "From our previous study, we established that cyclin A1 (CCNA1) promoter methylation is strongly correlated with multistep progression of HPV-associated cervical cancer, suggesting potential use as a diagnostic maker of disease. "
07/01/2011 - "Our previous study explored the very high degree of cyclin A1 (CCNA1) promoter methylation in invasive cervical cancer in which all cases were infected by HPV. "
03/08/2006 - "The aim of this study was to evaluate epigenetic status of cyclin A1 in human papillomavirus-associated cervical cancer. "
07/01/2011 - "Human papillomavirus's physical state and cyclin A1 promoter methylation in cervical cancer."
03/08/2006 - "We demonstrated cyclin A1 methylation to be commonly found in cervical cancer, both in vitro and in vivo, with its physiological role being to decrease gene expression. "

03/15/1999 - "In this study, we showed that cyclin A1 was highly expressed in a subset of leukemia samples from patients. "
06/01/2021 - "Here, we demonstrated that cyclin A1 suppression elicited the development of transient PI tolerance in mixed-lineage leukemia (MLL) cells. "
06/15/2008 - "Ablation of acinus or SRPK2 abrogates cyclin A1 expression in leukemia cells and arrest cells at G(1) phase. "
08/15/2007 - "DNA damage response involves modulation of Ku70 and Rb functions by cyclin A1 in leukemia cells."
02/01/2006 - "Exogenous WTA gene could inhibit the proliferation and colony forming ability of leukemia cells through up-regulating the expression of p21 and Cyclin A1 and arresting cell cycle at S phase."

01/01/2016 - "Cyclin A1 overexpression in the stem-like ALDH(high) subpopulation of PC3M cells, one model of prostate cancer, enabled bone marrow integration and metastatic growth. "
07/16/2008 - "Cyclin A1 is a cell cycle regulator that has been implicated in the progression of prostate cancer. "
07/16/2008 - "Multiple cellular mechanisms related to cyclin A1 in prostate cancer invasion and metastasis."
09/22/2005 - "However, a role of cyclin A1 in tumorigenesis of prostate cancer has not been reported. "
09/22/2005 - "In the present study, expression of cyclin A1 in patients with prostate cancer and a role of cyclin A1 in mediating expression of vascular endothelial growth factor (VEGF) were investigated. "

12/01/2013 - "Outstandingly, previous studies have also demonstrated the abnormal expression of cyclin A1 in various human tumors. "
10/15/2016 - "Enforced expression of cyclin A1 in cells containing mutant H2A.Z.1 rescued tumor formation in a mouse model. "
10/01/2015 - "Cyclin A1 (CCNA1) promoter methylation is strongly associated with HPV-associated cancer. "
01/01/2015 - "The purpose of this meta-analysis was to determine whether the aberrant methylation of cyclin A1 (CCNA1) may be of great significance to human malignant tumors. "
12/01/2013 - "How male germ cell-specific cyclin A1 is transcriptionally activated in tumor cells, however, is elusive. "

03/08/2006 - "More important, this study demonstrated that not only is cyclin A1 promoter hypermethylation strikingly common in cervical cancer, but is also specific to the invasive phenotype in comparison with other histopathological stages during multistep carcinogenesis. "
07/01/2019 - "Dysregulation of cyclin A1 (CCNA1) is implicated in the carcinogenesis, progression and metastasis of many types of solid tumours. "
09/22/2005 - "However, a role of cyclin A1 in tumorigenesis of prostate cancer has not been reported. "
02/10/2003 - "Its known oncogenic function and the high expression levels in aggressive testicular tumors suggest a role for cyclin A1 in germ cell tumorigenesis."
04/27/2004 - "The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1."