HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Donohue Syndrome

Rare autosomal recessive syndrome of extreme insulin resistance due to mutations in the binding domain of INSULIN RECEPTOR. Clinical features include severe intrauterine and postnatal growth restriction, characteristic dysmorphic FACIES; HIRSUTISM; VIRILIZATION; multiple endocrine abnormalities, and early death.
Also Known As:
Pineal Hyperplasia, Insulin-Resistant Diabetes Mellitus, And Somatic Abnormalities; Leprechaunisms; Rabson Mendenhall Syndrome; Syndrome, Donohue; Syndrome, Mendenhall; Syndrome, Rabson-Mendenhall; Leprechaunism; Mendenhall Syndrome; Rabson-Mendenhall Syndrome
Networked: 206 relevant articles (3 outcomes, 9 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Insulin Resistance
2. Weight Gain
3. Exocrine Pancreatic Insufficiency
4. Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
5. Hyperglycemia

Experts

1. Cochran, Elaine: 4 articles (01/2022 - 04/2004)
2. Barbetti, Fabrizio: 3 articles (01/2022 - 12/2013)
3. Galderisi, Alfonso: 3 articles (01/2022 - 12/2013)
4. Lascols, Olivier: 3 articles (11/2020 - 01/2016)
5. Kadowaki, Hiroko: 3 articles (05/2020 - 01/2010)
6. Semple, Robert K: 3 articles (01/2014 - 08/2007)
7. Brown, Rebecca J: 2 articles (01/2022 - 11/2013)
8. Niedziela, Marek: 2 articles (12/2021 - 01/2010)
9. Rojek, Aleksandra: 2 articles (12/2021 - 01/2010)
10. Choi, Jin-Ho: 2 articles (01/2021 - 01/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Donohue Syndrome:
1. Insulin (Novolin)FDA Link
2. EnzymesIBA
3. recombinant methionyl human leptinIBA
4. Insulin ReceptorIBA
5. Insulin-Like Growth Factor I (IGF-1)IBA
6. Biological ProductsIBA
7. Anabolic AgentsIBA
8. Blood Glucose (Blood Sugar)IBA
9. Glucose (Dextrose)FDA LinkGeneric
10. Nonsense Codon (Nonsense Mutation)IBA

Therapies and Procedures

1. Therapeutics
2. Subcutaneous Infusions
3. Anesthesia
4. Lasers (Laser)