Type 1 von Willebrand Disease

A subtype of von Willebrand disease that results from a partial deficiency of VON WILLEBRAND FACTOR.
Also Known As:
von Willebrand Disease, Type 1; Type I von Willebrand Disease; von Willebrand Disease, Type I
Networked: 123 relevant articles (6 outcomes, 17 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Hemophilia A (Haemophilia)
2. Hemorrhage
3. von Willebrand Diseases (von Willebrand's Disease)
4. Thrombosis (Thrombus)
5. Disease Susceptibility (Diathesis)


1. Castaman, G: 9 articles (09/2010 - 03/2000)
2. Rodeghiero, F: 9 articles (09/2010 - 03/2000)
3. Castaman, Giancarlo: 8 articles (05/2013 - 01/2007)
4. Goodeve, Anne: 8 articles (05/2013 - 01/2007)
5. Rodeghiero, Francesco: 8 articles (03/2013 - 01/2007)
6. Eikenboom, Jeroen: 7 articles (05/2013 - 01/2007)
7. Batlle, Javier: 7 articles (03/2013 - 01/2007)
8. Lethagen, Stefan: 6 articles (01/2015 - 01/2007)
9. Schneppenheim, Reinhard: 6 articles (01/2015 - 01/2007)
10. Budde, Ulrich: 6 articles (03/2013 - 01/2007)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Type 1 von Willebrand Disease:
1. von Willebrand FactorIBA
2. Deamino Arginine Vasopressin (Desmopressin)FDA LinkGeneric
3. Factor VIII (Coagulation Factor VIII)IBA
08/01/2013 - "Safety and pharmacokinetics (PK) of recombinant von Willebrand factor (rVWF) combined at a fixed ratio with recombinant factor VIII (rFVIII) were investigated in 32 subjects with type 3 or severe type 1 von Willebrand disease (VWD) in a prospective phase 1, multicenter, randomized clinical trial. "
02/01/1994 - "We report the case of a family with type I von Willebrand disease (vWD), characterized by a quantitative defect in von Willebrand factor (vWF), associated with a defective binding of vWF to factor VIII (FVIII) also called the "Normandy" variant of vWD. "
09/01/2009 - "We report the successful management of a craniosynostosis repair in a child with severe Type I von Willebrand disease diagnosed during the preoperative assessment and treated by coagulation factor VIII and ristocetin cofactor. "
06/01/2001 - "Studies are in progress, first to better characterize patients with type I von Willebrand disease and to determine their response to desmopressin, and second, to evaluate the pharmacokinetics of factor VIII following factor VIII/von Willebrand factor concentrates and to establish the indication for concentrates."
05/01/2013 - "The aim of treatment is to correct the dual defect of hemostasis caused by the abnormal/reduced von Willebrand factor and the concomitant deficiency of factor VIII. Desmopressin is the treatment of choice for type 1 von Willebrand disease patients with factor VIII and von Willebrand factor levels of 10 U/dL or over who have proved responsive to a test-infusion with the compound. "
4. AntigensIBA
5. Vasopressins (Vasopressin)IBA
6. Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
7. fibrin fragment D (D-dimer)IBA
8. Von Willebrand antigenIBA
9. Biological Markers (Surrogate Marker)IBA
10. Proteins (Proteins, Gene)IBA

Therapies and Procedures

1. Epidural Analgesia
2. Epidural Anesthesia
3. Off-Pump Coronary Artery Bypass (Coronary Artery Bypass, Off Pump)
4. Oral Surgery (Maxillofacial Surgery)
5. Rhinoplasty