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Chromatin Assembly Factor-1

A histone chaperone protein that plays a role in the deposition of NUCLEOSOMES on newly synthesized DNA. It is comprised of three different subunits of 48, 60, and 150 kDa molecular size. The 48 kDa subunit, RETINOBLASTOMA-BINDING PROTEIN 4, is also a component of several other protein complexes involved in chromatin remodeling.
Also Known As:
Chromatin Assembly Complex-1; Chromatin Assembly Complex-1, p150 Subunit; Chromatin Assembly Complex-1, p60 Subunit; Assembly Complex-1, Chromatin; Assembly Factor-1, Chromatin; Chromatin Assembly Complex 1; Chromatin Assembly Complex 1, p150 Subunit; Chromatin Assembly Complex 1, p60 Subunit; Chromatin Assembly Factor 1
Networked: 34 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Mascolo, Massimo: 7 articles (05/2021 - 04/2009)
2. Staibano, Stefania: 6 articles (05/2021 - 04/2009)
3. Ilardi, Gennaro: 6 articles (01/2021 - 04/2009)
4. De Rosa, Gaetano: 4 articles (12/2012 - 04/2009)
5. Russo, Daniela: 3 articles (05/2021 - 01/2012)
6. Merolla, Francesco: 3 articles (01/2021 - 01/2012)
7. Vecchione, Maria Luisa: 3 articles (12/2012 - 02/2010)
8. Varricchio, Silvia: 2 articles (05/2021 - 01/2021)
9. Celetti, Angela: 2 articles (01/2021 - 12/2012)
10. Mascolo, M: 2 articles (02/2017 - 06/2007)

Related Diseases

1. Neoplasms (Cancer)
2. Retinoblastoma (Glioblastoma, Retinal)
3. Stomach Neoplasms (Stomach Cancer)
4. Genomic Instability
5. Systemic Lupus Erythematosus (Libman-Sacks Disease)

Related Drugs and Biologics

1. Ligands
2. Proteins (Proteins, Gene)
3. Chromatin
4. Proliferating Cell Nuclear Antigen (PCNA)
5. Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)
6. DNA (Deoxyribonucleic Acid)
7. Histones (Histone)
8. Carrier Proteins (Binding Protein)
9. Autoantibodies
10. Nestin