Chronic Drug-Induced Liver Injury

Liver disease lasting six months or more, caused by an adverse drug effect. The adverse effect may result from a direct toxic effect of a drug or metabolite, or an idiosyncratic response to a drug or metabolite.

Also Known As:

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Drug-Induced Liver Injury

Experts

1.	Chalasani, Naga: 1 article (11/2015)
2.	Stine, Jonathan G: 1 article (11/2015)
3.	Uehara, Takeki: 1 article (10/2014)
4.	Kaneto, Masako: 1 article (10/2014)
5.	Ohno, Yasuo: 1 article (10/2014)
6.	Morikawa, Yuji: 1 article (10/2014)
7.	Urushidani, Tetsuro: 1 article (10/2014)
8.	Ono, Atsushi: 1 article (10/2014)
9.	Hanafusa, Hiroyuki: 1 article (10/2014)
10.	Yamada, Hiroshi: 1 article (10/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Chronic Drug-Induced Liver Injury:

1.	CytokinesIBA 10/03/2014 - "Comparative gene and protein expression analyses of a panel of cytokines in acute and chronic drug-induced liver injury in rats."
2.	Methionine (L-Methionine)FDA Link 01/01/2011 - "[Induction of endogenous s-adenosyl-l-methionine in hepatocytes during pharmacological correction of experimental acute toxic and chronic drug-induced liver injury]." 01/01/2011 - "The level of endogenous S-adenosyl-L-methionine (SAM) production during pharmacological correction of acute toxic (tetrachloromethane) and chronic drug-induced liver injury treated by remaxol, exogenous ademethionine, and reamberin has been studied on 118 outbred male rats. "
3.	Carbon Tetrachloride (Tetrachloromethane)IBA 01/01/2011 - "The level of endogenous S-adenosyl-L-methionine (SAM) production during pharmacological correction of acute toxic (tetrachloromethane) and chronic drug-induced liver injury treated by remaxol, exogenous ademethionine, and reamberin has been studied on 118 outbred male rats. "
4.	AutoantibodiesIBA 01/01/2010 - "High titer autoantibodies are found in patients with chronic drug induced liver injury." 01/01/2010 - "To investigate the clinical significance of liver function and autoantibodies in patients with acute or chronic drug-induced liver injury. " 01/01/2010 - "[Clinical significance of liver function and autoantibodies in patients with acute or chronic drug-induced liver injury]." 01/01/2010 - "51 patients with drug-induced liver injury were divided into acute drug induced liver injury group and chronic drug induced liver injury group, liver function and autoantibodies were compared between these two groups. "
5.	ReamberinIBA 01/01/2011 - "The level of endogenous S-adenosyl-L-methionine (SAM) production during pharmacological correction of acute toxic (tetrachloromethane) and chronic drug-induced liver injury treated by remaxol, exogenous ademethionine, and reamberin has been studied on 118 outbred male rats. "

Therapies and Procedures

1.	Individualized Medicine 11/01/2015 - "More study into pharmacogenomics and personalized medicine may aid in predicting which patients will go on to develop chronic drug-induced liver injury. "