Diffuse Neurofibrillary Tangles with Calcification

A form of presenile DEMENTIA characterized by cortical dementia, NEUROFIBRILLARY TANGLES without SENILE PLAQUES, Fahr's type CALCINOSIS, and ATROPHY in frontotemporal or TEMPORAL LOBE.

Also Known As:

Networked: 24 relevant articles (0 outcomes, 3 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Amyloid Plaque
2.	Dementia (Dementias)
3.	Alzheimer Disease (Alzheimer's Disease)
4.	Atrophy
5.	Diffuse Neurofibrillary Tangles with Calcification

Experts

1.	Tsuchiya, Kuniaki: 4 articles (02/2011 - 10/2002)
2.	Kuroda, S: 4 articles (12/2001 - 08/2000)
3.	Terada, S: 4 articles (12/2001 - 08/2000)
4.	Ishizu, H: 4 articles (12/2001 - 08/2000)
5.	Haraguchi, T: 4 articles (12/2001 - 08/2000)
6.	Akiyama, Haruhiko: 3 articles (02/2011 - 07/2005)
7.	Ishihara, Ryoko: 3 articles (02/2011 - 08/2003)
8.	Shibayama, Hiroto: 3 articles (02/2011 - 08/2003)
9.	Ikeda, K: 3 articles (06/2002 - 05/2001)
10.	Tsuchiya, K: 3 articles (06/2002 - 05/2001)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Diffuse Neurofibrillary Tangles with Calcification:

1.	4- N,N- dimethylamino- 1- naphthylisothiocyanateIBA 10/01/2009 - "In this study, the appearance and distribution of neurofibrillary tangles (NFT) in diffuse neurofibrillary tangles with calcification (DNTC) were investigated neuropathologically in order to elucidate the detailed distribution pattern in this disease. " 08/01/2003 - "In the present study the occurrence and distribution of glial fibrillary tangles (GFT) and their related structures in diffuse neurofibrillary tangles with calcification (DNTC) were investigated using Gallyas-Braak (GB) stain. " 06/01/2012 - "Parkinsonian features in a patient with diffuse neurofibrillary tangles with calcification (DNTC)." 12/01/2011 - "[Diffuse neurofibrillary tangles with calcification (DNTC)]." 12/01/2009 - "These characteristic neuropathologic findings lead to the pathologic diagnosis of diffuse neurofibrillary tangles with calcification (DNTC). "
2.	alpha-SynucleinIBA 06/01/2003 - "Alpha-synuclein-positive structures in association with diffuse neurofibrillary tangles with calcification." 10/01/2002 - "NACP/alpha-synuclein immunoreactivity in diffuse neurofibrillary tangles with calcification (DNTC)." 06/01/2003 - "However, no studies have reported alpha-synuclein-positive structures in cases of diffuse neurofibrillary tangles with calcification (DNTC), which is characterized by numerous neurofibrillary tangles (NFTs) throughout the cerebral cortex but few, if any, senile plaques. "
3.	UbiquitinIBA 08/01/2005 - "Silver staining profiles of argyrophilic grains (AGs) and of neurofibrillary tangles (NFTs) of diffuse neurofibrillary tangles with calcification (DNTC, collectively as DNTC-NFTs) were examined for their relation to tau- and ubiquitin-like immunoreactivity (IR). "
4.	Protein Isoforms (Isoforms)IBA 10/01/2006 - "In the second part, to better define the tau isoform composition, we report on the immunohistochemistry of tau isoforms in autopsied brains, including two cases with AD, two with diffuse neurofibrillary tangles with calcification, four with Pick's disease with Pick bodies (PiD), seven with progressive supranuclear palsy (PSP), six with corticobasal degeneration (CBD) and seven cases with argyrophilic grain disease. "
5.	SilverIBA 08/01/2005 - "Silver staining profiles of argyrophilic grains (AGs) and of neurofibrillary tangles (NFTs) of diffuse neurofibrillary tangles with calcification (DNTC, collectively as DNTC-NFTs) were examined for their relation to tau- and ubiquitin-like immunoreactivity (IR). "