Vasa Previa

Pregnancy complication where fetal blood vessels, normally inside the umbilical cord, are left unprotected and cross FETAL MEMBRANES. It is associated with antepartum bleeding and FETAL DEATH and STILLBIRTH due to exsanguination.

Also Known As:

Networked: 36 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Hemorrhage
2.	Placenta Previa
3.	Rupture
4.	Placenta Accreta
5.	Premature Birth (Birth, Premature)

Experts

1.	Rebarber, Andrei: 2 articles (01/2014 - 10/2008)
2.	Kontopoulos, Eftichia V: 2 articles (05/2010 - 12/2007)
3.	Quintero, Rubén A: 2 articles (05/2010 - 12/2007)
4.	Lim, Kenneth Ian: 2 articles (01/2010 - 08/2009)
5.	Delisle, Marie-France: 2 articles (01/2010 - 08/2009)
6.	Basso, Melanie: 2 articles (01/2010 - 08/2009)
7.	Morin, Lucie: 2 articles (01/2010 - 08/2009)
8.	Pressey, Tracy: 2 articles (01/2010 - 08/2009)
9.	Maternal Fetal Medicine Committee: 2 articles (01/2010 - 08/2009)
10.	Bly, Stephen: 2 articles (01/2010 - 08/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Vasa Previa:

1.	Fetal Hemoglobin (Hemoglobin F)IBA 05/15/1979 - "The various clinical pictures which can be associated with vasa previa are presented, along with a discussion of the techniques readily available for making the diagnosis: palpation and visualization, amnioscopy, fetal heart monitoring, and various tests for the presence of fetal hemoglobin." 12/01/1996 - "The Ogita test is the best all round alkaline denaturation test that may help to rapidly identify the presence of fetal hemoglobin and so establish the need to expedite delivery when there is fetal bleeding from vasa previa. " 04/01/2007 - "An easy-to-use method for detecting fetal hemoglobin--a test to identify bleeding from vasa previa." 08/01/2009 - "(II-2B) 6. In a woman with an antenatal diagnosis of vasa previa, when there has been bleeding or premature rupture of membranes, the woman should be offered delivery in a birthing unit with continuous electronic fetal heart rate monitoring and, if time permits, a rapid biochemical test for fetal hemoglobin, to be done as soon as possible; if any of the above tests are abnormal, an urgent Caesarean section should be performed. " 12/01/1996 - "To evaluate different alkaline denaturation tests and compare with hemoglobin electrophoresis and the Kleihauer test, and to identify the simplest and most sensitive test that may help to rapidly show the presence of fetal hemoglobin and establish the diagnosis of fetal bleeding from vasa previa. "
2.	Hemoglobins (Hemoglobin)IBA 12/01/1996 - "To evaluate different alkaline denaturation tests and compare with hemoglobin electrophoresis and the Kleihauer test, and to identify the simplest and most sensitive test that may help to rapidly show the presence of fetal hemoglobin and establish the diagnosis of fetal bleeding from vasa previa. "
3.	glucuronyl glucosamine glycan sulfate (Vessel)IBA 01/01/2014 - "Vasa previa was defined as a fetal vessel within 2 cm of the internal cervical os on transvaginal sonography. " 06/01/1999 - "We tried to find evidence of vasa previa in color and pulsed Doppler (a fetal vessel in seen above the lower segment of the uterus and below the fetal head. " 01/01/1991 - "The risk of vasa praevia should be considered (a) when ultrasonography has shown a bilobed or succenturiate placenta, a low-lying placenta where the cord has a battledore insertion, a migrating placenta, or a suspicion of velamentous vessel traversing the internal os, (b) when there is a multiple or IVF pregnancy, or (c) when there is intrapartum bleeding or an irregularity in fetal heart rate. " 08/01/1997 - "Review of the literature supports that prenatal ultrasound may outline normal anatomy or alternatively depict various congenital abnormalities of the umbilical cord including: cysts; pseudocysts; umbilical vein varix; persistent right umbilical vein; hemangiomas; umbilical vessel aneurysm (arterial or venous); single, hypoplastic, or fused umbilical artery; hematomas (spontaneous or iatrogenic); velamentous insertion; and vasa previa. "
4.	Adrenal Cortex Hormones (Corticosteroids)IBA 11/01/2015 - "Management of prenatally diagnosed vasa previa includes antenatal corticosteroids between 28-32 weeks of gestation, considerations for preterm hospitalization at 30-34 weeks of gestation, and scheduled delivery at 34-37 weeks of gestation. " 08/01/2009 - "(II-1A) 5. In cases of vasa previa, premature delivery is most likely; therefore, consideration should be given to administration of corticosteroids at 28 to 32 weeks to promote fetal lung maturation and to hospitalization at about 30 to 32 weeks. " 10/01/2008 - "Serial surveillance for signs of preterm labor and elective cesarean delivery at 34 to 35 weeks after corticosteroids for fetal lung maturity is a reasonable management strategy for vasa previa in multiple gestations."
5.	Fibronectins (Fibronectin)IBA 11/01/2013 - "Management of vasa praevia: a potential role for cervical length and quantitative fetal fibronectin measurement."
6.	antineoplaston A10 (A 10)IBA 12/01/1998 - "Vasa previa in Ramathibodi Hospital: a 10 years review."

Therapies and Procedures

1.	Cesarean Section (Caesarean Section) 01/01/2010 - "Published literature on randomized trials prospective cohort studies, and selected retrospective cohort studies was retrieved through searches of PubMed or Medline, CINAHL, and the Cochrane Library, using appropriate controlled vocabulary (e.g., selected epidemiological studies comparing delivery by Caesarean section with vaginal delivery studies comparing outcomes when vasa previa is diagnosed antenatally vs.intrapartum) and key words (e.g. " 08/01/2009 - "Published literature on randomized trials, prospective cohort studies, and selected retrospective cohort studies was retrieved through searches of PubMed or Medline, CINAHL, and the Cochrane Library, using appropriate controlled vocabulary (e.g., selected epidemiological studies comparing delivery by Caesarean section with vaginal delivery; studies comparing outcomes when vasa previa is diagnosed antenatally vs. intrapartum) and key words (e.g., vasa previa). " 07/01/2012 - "Identification of vasa praevia by the 3rd trimester of pregnancy warrants the offer of delivery by planned caesarean section to avoid the complications. " 02/01/2010 - "The majority of them would offer an elective Cesarean section for vasa previa at around 38 weeks. " 02/01/2010 - "Most respondents (80%) would offer an elective Cesarean section if vasa previa was suspected antenatally; the majority would perform it at 38 weeks' gestation. "
2.	Laser Therapy (Surgery, Laser) 10/01/2015 - "Fetoscopic laser ablation of vasa previa in pregnancy complicated by giant fetal cervical lymphatic malformation." 01/01/2014 - "Fetoscopic laser ablation of type II vasa previa allows for the possibility of term vaginal delivery. " 05/01/2010 - "As a therapeutic alternative to outright preterm delivery, the patient underwent uncomplicated laser ablation of the vasa previa. " 05/01/2010 - "In case 1, fetoscopic laser ablation of the vasa previa was performed without complication at 28 3/7 weeks' gestation as a prophylactic measure. " 05/01/2010 - "Two cases of type II vasa previa were identified via endovaginal ultrasound in the second trimester and treated via third trimester fetoscopic laser ablation. "
3.	Lasers (Laser) 12/01/2007 - "In utero laser treatment of type II vasa previa." 01/01/2014 - "We present a patient who underwent successful laser photocoagulation of a type II vasa previa at 32(5)/7 weeks' gestation. " 01/01/2014 - "Term vaginal delivery following fetoscopic laser photocoagulation of type II vasa previa." 05/01/2010 - "We suggest that type II vasa previa can be definitively treated in utero by laser photocoagulation in the third trimester. "
4.	Resuscitation 12/01/2014 - "For this reason, pregnant women with risk factors of vasa praevia should be examined using transvaginal ultrasound in combination with colour Doppler, and if the diagnosis is made, elective delivery by caesarean and aggressive resuscitation of the new born is indicated. " 08/01/2009 - "(III-B) 7. Women admitted with diagnosed vasa previa should ideally be transferred for delivery in a tertiary facility where a pediatrician and blood for neonatal transfusion are immediately available in case aggressive resuscitation of the neonate is necessary. "
5.	Light Coagulation 01/01/2014 - "We present a patient who underwent successful laser photocoagulation of a type II vasa previa at 32(5)/7 weeks' gestation. " 01/01/2014 - "Term vaginal delivery following fetoscopic laser photocoagulation of type II vasa previa." 05/01/2010 - "We suggest that type II vasa previa can be definitively treated in utero by laser photocoagulation in the third trimester. "