Halo Nevus

02/01/1985 - "Fifteen halo nevi were stained for the presence of S100 protein by an unlabelled antibody peroxidase-antiperoxidase method. "
09/01/1983 - "In control studies, S-100 protein was found using an unlabeled antibody peroxidase-antiperoxidase technic within nevus cells composing junctional intradermal, and compound nevi, Spitz nevi, and halo nevi. "

09/01/1983 - "In control studies, S-100 protein was found using an unlabeled antibody peroxidase-antiperoxidase technic within nevus cells composing junctional intradermal, and compound nevi, Spitz nevi, and halo nevi. "

01/01/2012 - "We analyzed 30 halo nevi and performed immunohistochemical analysis using antibodies against CD4, CD8, CD25 and Foxp3. "
08/01/1994 - "We studied the morphological features of the nevus cells and the composition of the mononuclear cell infiltrate in 15 cases of halo nevi using immunohistochemical techniques and a battery of antibodies to different subsets of lymphocytes and histiocytes. "
05/01/2004 - "Twenty-seven specimens, nine each of halo nevus, keratoacanthoma, and benign lichenoid keratosis, including three examples each of predominantly early, mid, and late regression were examined with antibodies to HLA-II, CD1a, CD3, CD4, CD8, CD20, CD34, CD56, and CD68. "
11/01/1997 - "There were no obvious differences in immunohistochemical staining patterns among 4 Spitz's nevi with halo reaction, 5 regressing melanomas, and 5 benign halo nevi when stained with antibodies to S100, HMB-45, OPD4, CD8, TIA-1, CD1a, CD68, and Ki-67."

06/01/2004 - "Human leukocyte antigen (HLA) class II associations with two subtypes of vitiligo: vitiligo vulgaris and halo nevi associated with vitiligo were investigated. "
07/01/1985 - "It was found that the vast majority of the nevomelanocytes in halo nevi with a dense inflammatory infiltrate markedly expressed HLA-A,B,C antigens, while expression was not demonstrable in nevocellular nests not adjacent to the mononuclear infiltrate. "
07/01/1985 - "These results demonstrate that the expression of HLA-A,B,C antigens on the nevomelanocytes and the cellular composition of the mononuclear inflammatory infiltrate in halo nevi are very similar to that in malignant melanomas and dysplastic neiv. "
07/01/1976 - "Various facets of cellular immunity were altered, namely: 1) a majority of the patients developed enhanced cutaneous reactions to the microbial skin-test antigens (particularly tuberculin) and tumor cells; 2) nine patients developed the equivalent of delayed hypersensitivity reactions or flares at all previous PPD and BCG inoculation sites following subsequent injection of these agents, which supports the concept of immunologic memory for these target antigens; 3) lesions resembling those of "spontaneous" regressed moles (halo-nevi) were observed at previous vaccine sites in 20 patients and generalized depigmentation occurred in three patients; 4) foreign body giant cells in tumor metastasis remote from BCG-PPD-tumor vaccine sites may indicate a cross-reactivity of microbial and tumor antigens; and 5) intralesional inoculation of the nonspecific agents (BCG, PPD, Varidase, and Mumps) resulted in dense mononuclear cell infiltration and complete regression of most of the injected lesions. "

01/01/1988 - "Immunohistochemical techniques using monoclonal antibodies distinguished this condition from halo nevus. "
07/01/1985 - "A series of monoclonal antibodies was used to characterize the nevomelanocytes and the inflammatory infiltrate of 11 halo nevi in different stages of resolution, employing an immunoperoxidase technique. "
06/01/1983 - "This review describes the current state of the art and provides several illustrations of the use of monoclonal antibodies for the identification of T-lymphocyte phenotypes in frozen section from cases of leprosy, mycosis fungoides, halo nevus, Kaposi's sarcoma, lichen planus and atopic dermatitis. "

05/01/2015 - "Granzyme, PD1, and TIA-1 stained significantly more cells in halo nevi than in melanomas with regression (P < 0.01). "
07/01/2005 - "Detailed immunohistologic analyses, including expression of MxA (an antiviral protein specifically induced by type I interferons), the chemokine IP10/CXCL10, the chemokine receptor CXCR3, and the cytotoxic molecule granzyme B, were performed for 14 typical regressive tumors and 20 control samples (congenital nevi, halo nevi, unaffected skin). "

01/01/2012 - "Halo nevi associated with interferon beta-1a therapy."
01/01/2012 - "[Halo nevi associated with interferon beta-1a therapy]."

07/01/2005 - "Detailed immunohistologic analyses, including expression of MxA (an antiviral protein specifically induced by type I interferons), the chemokine IP10/CXCL10, the chemokine receptor CXCR3, and the cytotoxic molecule granzyme B, were performed for 14 typical regressive tumors and 20 control samples (congenital nevi, halo nevi, unaffected skin). "

04/01/2007 - "Fibrogenic cytokines, IL-6, platelet-derived growth factor, and transforming growth factor-beta were only expressed in melanoma, whereas basic fibroblastic growth factor was also expressed in halo nevus. "

04/01/2007 - "At ultrastructural level, melanocytes showed a more activated status in regressing melanoma than in halo nevus, in compliance with a milieu richer in cytokines. "
04/01/2007 - "Fibrogenic cytokines were more frequently expressed in melanoma than in halo nevus, irrespective of regression. "
04/01/2007 - "Six halo nevi, seven regressing primary melanomas, and seven primary melanoma (PM) without regression were studied using immunohistochemistry for the phenotype of inflammatory infiltrate and the expression of cytokines involved in fibrogenesis or macrophage regulation. "
04/01/2007 - "Fibrogenic cytokines, IL-6, platelet-derived growth factor, and transforming growth factor-beta were only expressed in melanoma, whereas basic fibroblastic growth factor was also expressed in halo nevus. "

12/01/2007 - "Treatment with the 308-nm excimer laser may be an effective treatment of halo nevi located on the face."
12/01/2007 - "To assess the efficacy of excimer laser for the treatment of halo nevus. "
12/01/2008 - "Treatment of halo nevus with 308-nm excimer laser: a pilot study."
12/01/2007 - "Four patients with halo nevus on the face were treated by excimer laser three times a week until they achieved 75% pigmentation or a maximum of 36 treatment sessions. "
12/01/2007 - "Treatment of halo nevus with a 308-nm excimer laser: a pilot study."

11/01/2011 - "Cutaneous halo nevi following plaque radiotherapy for uveal melanoma."