Viscosupplementation

A therapeutic treatment typically involving INTRA-ARTICULAR INJECTIONS of HYALURONIC ACID and related compounds. The procedure is commonly used in the treatment of OSTEOARTHRITIS with the therapeutic goal to restore the viscoelasticity of SYNOVIAL FLUID, decrease pain, improve mobility and restore the natural protective functions of hyaluronan in the joint.

Also Known As:

Networked: 385 relevant articles (63 outcomes, 46 trials/studies)

Relationship Network

Therapy Context: Research Results

Experts

1.	Conrozier, Thierry: 18 articles (12/2021 - 03/2003)
2.	Migliore, Alberto: 13 articles (08/2022 - 01/2006)
3.	Chevalier, Xavier: 12 articles (12/2021 - 07/2008)
4.	Henrotin, Yves: 7 articles (12/2021 - 10/2015)
5.	Richette, Pascal: 7 articles (12/2021 - 10/2015)
6.	Waddell, David D: 7 articles (06/2010 - 10/2003)
7.	Bard, Hervé: 6 articles (12/2021 - 10/2015)
8.	Baron, Dominique: 6 articles (12/2021 - 01/2018)
9.	Jerosch, Jörg: 6 articles (12/2021 - 10/2015)
10.	Raman, Raghu: 6 articles (01/2021 - 10/2015)

Related Diseases

1.	Pain (Aches) 01/04/2022 - "Viscosupplementation after arthroscopic partial meniscectomy significantly reduced pain at 2 weeks post-surgery and improved ROM of the knee at 2 weeks post-surgery. " 01/01/2013 - "All KOOS subscales ('pain', 'symptoms', 'daily activities', 'sports' and 'quality of life') and the NRS pain improved significantly 14 weeks after Viscosupplementation with HA. " 11/01/2009 - "These data, collected from 78 young patients, show that viscosupplementation is a safe procedure, and may provide significant relief from pain and functional recovery. " 04/19/2006 - "Based on the aforementioned analyses, viscosupplementation is an effective treatment for OA of the knee with beneficial effects: on pain, function and patient global assessment; and at different post injection periods but especially at the 5 to 13 week post injection period. " 03/01/2006 - "WOMAC pain scores were improved at the first control visit in the TENS group and in the viscosupplementation group; this improvement was statistically significant. "
2.	Osteoarthritis 11/01/2009 - "Viscosupplementation of the hip for symptomatic osteoarthritis appears to be safe and effective in more than 25 yr of use in Europe. " 11/22/2023 - "Viscosupplementation is Effective for the Treatment of Osteoarthritis in the Hip. " 01/01/2021 - "Viscosupplementation (VS) is a safe and effective local treatment for osteoarthritis (OA) of the knee. " 09/01/2002 - "Viscosupplementation: a new treatment option for osteoarthritis." 01/01/2016 - "To evaluate the efficacy of viscosupplementation in patients with osteoarthritis of the ankle. "
3.	Knee Osteoarthritis 08/01/2008 - "Our findings show that AD is beneficial in osteoarthritis of the knee in patients with appropriate indications, viscosupplementation increases the efficacy of treatment, and that low- and high-molecular-weight HA preparations have similar efficacy." 09/01/2008 - "Likewise, viscosupplementation has proved to be efficacious in the management of osteoarthritis of the knee. " 09/01/2017 - "Randomized controlled trial comparing efficacy of conventional and new single larger dose of intra-articular viscosupplementation in management of knee osteoarthritis." 01/01/2016 - "Further large trials assessing the use of viscosupplementation across various formulations in knee osteoarthritis may confirm subgroup findings from meta-analyses; however, immediate focus on improved knowledge translation is required to ensure evidence-based approaches to the treatment of knee osteoarthritis." 04/01/2022 - "Improvement in condition specific and generic quality of life outcomes in patients with knee osteoarthritis following single intraarticular viscosupplementation injection."
4.	Hip Osteoarthritis (Coxarthrosis) 06/01/2005 - "Comparison of the efficacy of lower and higher molecular weight viscosupplementation in the treatment of hip osteoarthritis." 01/01/2022 - "Viscosupplementation is a safe and effective therapy for hip osteoarthritis, even in severe cases. " 08/27/2019 - "BACKGROUND The aim of this study was to review the efficacy and safety of intra-articular (IA) viscosupplementation (VS) for hip osteoarthritis (OA). " 09/01/2005 - "Double-blind, controlled studies are required to confirm these data, before viscosupplementation should be included into the treatment paradigm for patients with hip osteoarthritis." 06/01/2005 - "The aim of this study was to determine the efficacy and safety of viscosupplementation applied to the hip joint with the lateral approach and ultrasound guidance and to show whether this can be an alternative treatment model in hip osteoarthritis (OA). "
5.	Joint Diseases (Joint Disease) 01/01/2013 - "Viscosupplementation is a safe and effective therapeutic strategy in knee haemophilic arthropathy, with no complications, persisting good clinical results, and determining in most cases a delay of surgery." 10/01/2012 - "Further trials are required to ascertain whether viscosupplementation should be indicated in painful radiological haemophilic arthropathy of the knee." 08/01/2022 - "Such innovations in viscosupplementation expand the usefulness of the modality in the management of OA and other joint diseases, complemented by a lack of systemic or local side effects that allow the concurrent use of other drugs if needed." 08/01/2022 - "They represent progress in building on the symptomatic and functional benefits of viscosupplementation in joint disease, with the additional beneficial effect of treating the patient with a high concentration of GAGs by a low number of injections. " 04/01/2021 - "To report the effectiveness of temporomandibular joint (TMJ) arthrocentesis with viscosupplementation for degenerative joint disease (DJD) over a long-term (ie, 10-22 years) follow-up. "

Related Drugs and Biologics

1.	Hyaluronic Acid (Hyaluronan)
2.	hylan
3.	Adrenal Cortex Hormones (Corticosteroids)
4.	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)
5.	Polynucleotides
6.	Analgesics (Analgesic Drugs)
7.	Viscosupplements
8.	Steroids
9.	Phosphates (Orthophosphate)
10.	Glucosamine (Dona)

Related Therapies and Procedures

1.	Therapeutics
2.	Intra-Articular Injections
3.	Injections
4.	Meniscectomy
5.	Conservative Treatment