Mucin-5B

A gel-forming mucin that is predominantly expressed by submucosal glands of airway tissues and the SUBLINGUAL GLAND. It is one of the principal components of high molecular weight salivary mucin.

Also Known As:

Networked: 38 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Boucher, Richard C: 3 articles (01/2019 - 11/2018)
2.	Schwartz, David A: 3 articles (01/2017 - 01/2013)
3.	Abasubong, Kenneth Prudence: 2 articles (03/2022 - 08/2018)
4.	Li, Xiang-Fei: 2 articles (03/2022 - 08/2018)
5.	Liu, Wen-Bin: 2 articles (03/2022 - 08/2018)
6.	Bouma, Gerd: 2 articles (11/2020 - 01/2018)
7.	Brand, Henk S: 2 articles (11/2020 - 01/2018)
8.	de Boer, Nanne K: 2 articles (11/2020 - 01/2018)
9.	O'Neal, Wanda K: 2 articles (01/2019 - 11/2018)
10.	Hatabu, Hiroto: 2 articles (11/2018 - 06/2013)

Related Diseases

1.	Xerostomia 01/01/2017 - "Since Mucin 5B is effective for wetting and lubrication of the oral cavity, this result can suggest a possible reason for mouth dryness in OLP patients." 01/01/2017 - "This study aimed to assess the level of Mucin 5B in OLP patients with xerostomia. " 01/01/2018 - "The Xerostomia Inventory score (XI-score), the salivary flow rates, the concentrations of salivary amylase and mucin 5B, and the type of oral and dental complaints were evaluated. " 06/01/2013 - "Influence of SS flow rate (SSFR), calcium and mucin 5b (MUC5b) concentrations and radiation dose on xerostomia was determined. " 11/01/2020 - "Xerostomia Inventory score, (unstimulated/stimulated) salivary flow rates, salivary amylase and mucin/ Mucin 5B levels, self-reported oral and dental complaints, the oral health related quality of life, Simple Clinical Colitis Activity Index and inflammatory bowel disease-specific health related quality of life were determined. "
2.	Pulmonary Fibrosis (Fibrosing Alveolitis) 11/01/2018 - "A single-nucleotide polymorphism (rs35705950) in the mucin 5B (MUC5B) gene promoter is associated with pulmonary fibrosis and interstitial features on chest CT but may also have beneficial effects. " 03/01/2023 - "Mutations in the genes encoding telomerase reverse transcriptase (TERT) and mucin 5B (MUC5B) are well-known genetic risk factors for pulmonary fibrosis. " 07/22/2022 - "This study aimed to identify whether risk alleles of known genes linked with emphysema (SERPINA1) and pulmonary fibrosis (MUC5B) are associated with severe COVID-19, and whether plasma mucin 5B differs according to patients' outcomes. "
3.	Emphysema 07/22/2022 - "This study aimed to identify whether risk alleles of known genes linked with emphysema (SERPINA1) and pulmonary fibrosis (MUC5B) are associated with severe COVID-19, and whether plasma mucin 5B differs according to patients' outcomes. "
4.	Burns 03/01/2008 - "This study examines the localization of an upper airway gland specific mucus, mucin 5B (MUC5B) in lung autopsy tissues of burn-only injury and in victims of S + B injury. " 03/01/2008 - "Mucin 5B was seen in the parenchyma except in two burn victims. "
5.	COVID-19 07/22/2022 - "COVID-19 survivor patients bearing one or two copies of the rs35705950 risk allele have higher plasma levels of mucin 5B." 07/22/2022 - "COVID-19 Survivor Patients Carrying the Rs35705950 Risk Allele in MUC5B Have Higher Plasma Levels of Mucin 5B." 07/22/2022 - "This study aimed to identify whether risk alleles of known genes linked with emphysema (SERPINA1) and pulmonary fibrosis (MUC5B) are associated with severe COVID-19, and whether plasma mucin 5B differs according to patients' outcomes. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Mucins
3.	Muramidase (Lysozyme)
4.	Mucin 5AC
5.	Cytokines
6.	Protease Inhibitors (Protease Inhibitor)
7.	Calcium
8.	Amylases
9.	Fatty Acid Synthases (Fatty Acid Synthase)
10.	Occludin

Related Therapies and Procedures

1.	Precision Medicine
2.	Immunotherapy