Lincosamides

A family of LINCOMYCIN-related glycosides that contain a pyrrolidine ring linked via an amide-bond to a pyranose moiety. Individual members of this family are defined by the arrangement of specific constituent groups on the lyncomycin molecule. Many lincosamides are ANTIBIOTICS produced by a variety STREPTOMYCES species.

Networked: 70 relevant articles (3 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Abotsi, Regina E: 1 article (01/2022)
2.	Alonso-Téllez, César Alejandro: 1 article (01/2022)
3.	Barrón-Enríquez, Carolina: 1 article (01/2022)
4.	Barthus, Charmaine: 1 article (01/2022)
5.	Caballero-Trejo, Amilcar: 1 article (01/2022)
6.	Castro-Garza, Jorge: 1 article (01/2022)
7.	Cerda-Flores, Ricardo Martín: 1 article (01/2022)
8.	Dube, Felix S: 1 article (01/2022)
9.	Ferrand, Rashida A: 1 article (01/2022)
10.	Flores-Flores, Aldo Sebastián: 1 article (01/2022)

Related Diseases

1.	Staphylococcal Infections 01/01/2007 - "In order to prevent the development of constitutively resistant isolates under therapy, the results of this study support the recommendation not to use lincosamides or 16-membered macrolides for the control of staphylococcal infections caused by strains harbouring inducibly expressed erm(C) genes." 07/01/1985 - "A number of factors must be taken into consideration when comparing the relative efficacy of macrolides-lincosamides-streptogramins (MLS) in staphylococcal infections: these include their antibacterial activity, their pharmacokinetic characteristics, their tolerance, and the results achieved in clinical practice." 07/01/1985 - "Comparative evaluation of macrolides, lincosamides and streptogramins in staphylococcal infections."
2.	Toxoplasmosis 12/01/1988 - "This results confirm that macrolides, lincosamides are effective against Toxoplasma gondii in vitro, and can be proposed for treatment of toxoplasmosis because of their large diffusion, their good tolerance and their concentration in tissues such as lung and placenta."
3.	Erysipelas 10/01/2016 - "Beta-lactam antibiotics, such as penicillin, flucloxacillin or cephalexin, are widely considered first-line treatment for cellulitis and erysipelas, while macrolides and lincosamides, such as erythromycin, azithromycin or clindamycin, are widely considered second-line agents. "
4.	Cellulitis 10/01/2016 - "Beta-lactam antibiotics, such as penicillin, flucloxacillin or cephalexin, are widely considered first-line treatment for cellulitis and erysipelas, while macrolides and lincosamides, such as erythromycin, azithromycin or clindamycin, are widely considered second-line agents. "
5.	Infections 01/01/2015 - "Lincosamides were prescribed for the respiratory infections and other infections groups. " 01/01/2022 - "In addition, increasing resistance of GBS to macrolides and lincosamides has been reported, so knowing the patterns of antibiotic resistance may be necessary to prevent and treat GBS infections. " 05/01/2014 - "Macrolides and lincosamides are important antibacterials for the treatment of many common infections in cattle and pigs. " 04/01/1996 - "Epidemiological study of an outbreak of infection with Staphylococcus aureus resistant to lincosamides and streptogramin A in a French hospital." 06/13/2019 - "Individuals who are immunosuppressed, moribund, with current severe diarrhoea or Clostridiodes difficile infection, pregnant, and those with anaphylaxis to β-lactams or lincosamides will be excluded. "

Related Drugs and Biologics

1.	Macrolides
2.	Penicillins (Penicillin)
3.	Clindamycin (Cleocin)
4.	Erythromycin (Erycette)
5.	Azithromycin (Zithromax)
6.	Streptogramins
7.	beta Lactam Antibiotics
8.	Cephalexin (Cefalexin)
9.	Floxacillin (Flucloxacillin)
10.	Anti-Bacterial Agents (Antibiotics)

Related Therapies and Procedures

1.	Therapeutics
2.	Resuscitation