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Perivascular Epithelioid Cell Neoplasms

A family of mesenchymal tumors composed of histologically and immunohistochemically distinctive perivascular epithelioid cells. These cells do not have a normal anatomic homolog. (From Fletcher CDM, et. al., World Health Organization Classification of Tumors: Pathology and Genetics of Tumors of Soft Tissue and Bone, 2002).
Also Known As:
CCMMT; Neoplasms, Perivascular Epithelioid Cell; Perivascular Epithelioid Cell Tumors; Clear Cell Myomelanocytic Tumor; Clear Cell Myomelanocytic Tumors; Clear Cell Sugar Tumor; Clear Cell Sugar Tumors; Myomelanocytic Tumor, Clear-Cell; Myomelanocytic Tumors, Clear-Cell; Sugar Tumor, Clear-Cell; Sugar Tumors, Clear-Cell; Tumor, Clear-Cell Myomelanocytic; Tumor, Clear-Cell Sugar; Tumors, Clear-Cell Myomelanocytic; Tumors, Clear-Cell Sugar; Clear-Cell Myomelanocytic Tumor; Clear-Cell Myomelanocytic Tumors; Clear-Cell Sugar Tumor; Clear-Cell Sugar Tumors; PEComa; PEComas; Perivascular Epithelioid Cell Neoplasm; Perivascular Epithelioid Cell Tumor
Networked: 313 relevant articles (12 outcomes, 18 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Soft Tissue Neoplasms
3. Perivascular Epithelioid Cell Neoplasms
4. Tuberous Sclerosis (Bourneville's Disease)
5. Sarcoma (Soft Tissue Sarcoma)

Experts

1. Martignoni, Guido: 12 articles (05/2021 - 02/2008)
2. Argani, Pedram: 8 articles (05/2021 - 04/2009)
3. Kwiatkowski, David J: 7 articles (11/2021 - 02/2010)
4. Brunelli, Matteo: 7 articles (05/2021 - 01/2012)
5. Rao, Qiu: 7 articles (01/2020 - 03/2013)
6. Folpe, Andrew L: 6 articles (01/2012 - 06/2002)
7. Antonescu, Cristina R: 5 articles (01/2022 - 02/2010)
8. Gobbo, Stefano: 5 articles (05/2021 - 01/2010)
9. Xia, Qiu-Yuan: 5 articles (01/2020 - 06/2013)
10. Zhou, Xiao-Jun: 5 articles (01/2020 - 06/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Perivascular Epithelioid Cell Neoplasms:
1. MTOR InhibitorsIBA
2. Sirolimus (Rapamycin)FDA Link
3. Melanins (Melanin)IBA
4. Glycoproteins (Glycoprotein)IBA
5. lipoarabinomannan (LAM)IBA
6. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
7. Cathepsin KIBA
8. MART-1 AntigenIBA
9. Microphthalmia-Associated Transcription FactorIBA
10. Proteins (Proteins, Gene)FDA Link

Therapies and Procedures

1. Therapeutics
2. Immunotherapy
3. Drug Therapy (Chemotherapy)
4. Radiotherapy
5. Hysterectomy