Drug-Eluting Stents

Stents that are covered with materials that are embedded with chemicals that are gradually released into the surrounding milieu.

Also Known As:

Drug Coated Stent; Drug Coated Stents; Drug Eluting Stent; Drug Eluting Stents; Stent, Drug-Coated; Stent, Drug-Eluting; Stents, Drug Coated; Stents, Drug Eluting; Drug-Coated Stent; Drug-Coated Stents; Drug-Eluting Stent; Stents, Drug-Coated; Stents, Drug-Eluting

Networked: 4768 relevant articles (343 outcomes, 857 trials/studies)

Relationship Network

Therapy Context: Research Results

Equipment and Supplies
- Prostheses and Implants: 21690
  - Stents: 54558
    - Drug-Eluting Stents: 4768

Experts

1.	Serruys, Patrick W: 135 articles (01/2022 - 03/2002)
2.	Park, Seung-Jung: 121 articles (01/2022 - 01/2005)
3.	Stone, Gregg W: 116 articles (12/2021 - 03/2005)
4.	Jeong, Myung Ho: 107 articles (11/2022 - 10/2007)
5.	Hong, Myeong-Ki: 105 articles (11/2022 - 01/2005)
6.	Mehran, Roxana: 99 articles (10/2022 - 03/2005)
7.	Jang, Yangsoo: 94 articles (11/2022 - 06/2009)
8.	Kim, Young-Hak: 88 articles (01/2022 - 11/2005)
9.	Colombo, Antonio: 85 articles (12/2022 - 04/2002)
10.	Choi, Donghoon: 82 articles (11/2022 - 06/2009)

Related Diseases

1.	Coronary Artery Disease (Coronary Atherosclerosis) 07/25/2017 - "Current 2nd-generation drug-eluting stents (DES) have dramatically improved clinical outcomes after percutaneous coronary intervention for coronary artery disease. " 01/01/2011 - "Most available data indicates that stenting for unprotected left main coronary artery disease (ULMCA) with drug-eluting stents (DES) is safe and effective. " 01/01/2018 - "Drug eluting stents (DES) have been increasingly being used for treatment of coronary artery disease (CAD) and have been shown to be very effective in prevention of primary in-stent restenosis (ISR). " 08/01/2006 - "Drug-eluting stents have been shown to be very effective in the treatment of coronary artery disease. " 04/01/2006 - "In coronary artery disease, although drug eluting stents have improved the results of percutaneous coronary intervention, coronary artery bypass grafts have still has an important place in the treatment of severe lesions: multivessel disease, left main and diabetes. "
2.	Thrombosis (Thrombus) 01/01/2022 - "Although the introduction of drug-eluting stents (DES) dramatically reduced the risk of in-stent restenosis, stent thrombosis persists as an issue. " 05/01/2016 - "Although drug-eluting stents (DES) for percutaneous coronary intervention (PCI) have dramatically reduced the incidence of in-stent restenosis, their deployment for large-size coronary lesions is still controversial because of problems such as late in-stent thrombosis and late catch-up in DES. " 08/01/2013 - "Although drug-eluting stents have dramatically reduced angiographic restenosis and clinical need for repeat revascularization procedures, some adverse effects, such as late stent thrombosis, have been described. " 11/01/2012 - "Drug-eluting stents have dramatically reduced the risk of restenosis, but concerns of an increased risk of stent thrombosis have provided uncertainty about their use. " 07/01/2010 - "Drug-eluting stents (DES) are highly effective in reducing restenosis but have a small but significant risk for late stent thrombosis (LAST). "
3.	Myocardial Infarction 05/01/2019 - "This meta-analysis suggests that the drug-coated balloon strategy is noninferior to the drug-eluting stent strategy, delivering a good outcome in nonfatal myocardial infarction, and can be recommended as an optimal treatment strategy in patients with de novo small coronary artery vessel disease. " 12/07/2014 - "In the FAME 2 trial, fractional flow reserve-guided percutaneous coronary intervention with second generation drug eluting stents showed a significant reduction in the primary composite endpoint of 2-year mortality, myocardial infarction and unplanned hospitalization with urgent revascularisation as compared to medical therapy alone. " 06/01/2010 - "Drug-eluting stents are associated with a significant reduction in the 3-year cumulative rates of all-cause mortality, cardiovascular death, and myocardial infarction when compared to BMS. " 03/01/2010 - "Early data suggest that drug eluting stents reduce restenosis rates and the need for repeat revascularization irrespective of the diabetic state and with no significant reduction in hard clinical endpoints such as myocardial infarction and mortality. " 01/01/2010 - "Drug-eluting stents were not associated with a significant reduction in overall death (RR = 0.94; 95% CI, 0.74-1.20; P = 0.64), but were associated with significant reductions in recurrent myocardial infarction (RR = 0.76; 95% CI, 0.58-0.98; P = 0.03), target-vessel revascularization (RR = 0.47; 95% CI, 0.39-0.56; P <0.00001), and in-stent restenosis (RR = 0.32; 95% CI, 0.25-0.39; P < 0.00001). "
4.	ST Elevation Myocardial Infarction 03/01/2014 - "In an unselected nationwide real-world cohort, an approach using immediate complete revascularization may be beneficial in STEMI patients with MVD regarding MACCE, specifically when drug-eluting stents are used, but not regarding mortality. " 01/01/2022 - "Corrigendum: Safety and efficacy of contemporary drug-eluting stents in patients with ST-segment elevation myocardial infarction and a high ischemic risk." 01/01/2022 - "In patients with ST-elevation myocardial infarction (STEMI) with a high risk of ischemic events, the safety and efficacy of drug-eluting stent (DES) are unclear. " 01/01/2022 - "Safety and Efficacy of Contemporary Drug-Eluting Stents in Patients With ST-Segment Elevation Myocardial Infarction and a High Ischemic Risk." 01/01/2021 - "Primary percutaneous coronary intervention (PCI) is an effective treatment for patients with STEMI, and long-term outcomes are determined by the safety and efficacy profile of the newest generation drug-eluting stents. "
5.	Pathologic Constriction (Stenosis) 02/01/2007 - "In the era of drug-eluting stents that have dramatically reduced the re-stenosis rate, and in the context of the development of emerging modalities like magnetic resonance imaging (MRI) and multislice computed tomography that allow precise and non-invasive diagnosis, it becomes important to question whether and how fluoroscopic-based evaluation of cardiac structure and function shall evolve. " 11/01/2016 - "In contrast ostial stenosis of the left main trunk shows very good results after percutaneous interventions and implantation of drug-eluting stents. " 08/01/2022 - "The introduction of drug-eluting stents (DESs) have yield a significant reduction in the incidence of re-stenosis, however, challenges remain including incomplete healing of the endothelium, inflammatory response and thrombogenesis at the site of vascular wall injury. " 08/01/2010 - "The degree of in-stent stenosis was significantly reduced in the SES group, suggesting that the use of drug-eluting stents is an effective treatment for PVS. " 02/01/2009 - "Urgent coronary angiography showed severe LMCA stenosis caused by extrinsic compression from the pulmonary artery with no other lesions in the coronary arteries; coronary angioplasty was successfully performed with a direct drug-eluting stent implantation that led to a significant improvement of the haemodynamic conditions in the following days. "

Related Drugs and Biologics

1.	Metals
2.	Polymers
3.	Paclitaxel (Taxol)
4.	Sirolimus (Rapamycin)
5.	Clopidogrel (Plavix)
6.	omega-Chloroacetophenone (Mace)
7.	Aspirin (Acetylsalicylic Acid)
8.	Everolimus
9.	Cilostazol (Pletal)
10.	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)

Related Therapies and Procedures

1.	Stents
2.	Percutaneous Coronary Intervention
3.	Coronary Artery Bypass (Coronary Artery Bypass Surgery)
4.	Therapeutics
5.	Dual Anti-Platelet Therapy