Lecithins

A complex mixture of PHOSPHOLIPIDS; GLYCOLIPIDS; and TRIGLYCERIDES; with substantial amounts of PHOSPHATIDYLCHOLINES; PHOSPHATIDYLETHANOLAMINES; and PHOSPHATIDYLINOSITOLS, which are sometimes loosely termed as 1,2-diacyl-3-phosphocholines. Lecithin is a component of the CELL MEMBRANE and commercially extracted from SOYBEANS and EGG YOLK. The emulsifying and surfactant properties are useful in FOOD ADDITIVES and for forming organogels (GELS).

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Networked: 755 relevant articles (34 outcomes, 83 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Hazen, Stanley L: 3 articles (01/2015 - 09/2007)
2.	Togni, Stefano: 3 articles (03/2014 - 01/2013)
3.	Flicker, L: 3 articles (01/2003 - 01/2000)
4.	Ma, Yong: 2 articles (06/2015 - 04/2014)
5.	Tang, W H Wilson: 2 articles (01/2015 - 04/2013)
6.	Levison, Bruce S: 2 articles (01/2015 - 04/2013)
7.	Wu, Yuping: 2 articles (01/2015 - 04/2013)
8.	Wang, Zeneng: 2 articles (01/2015 - 04/2013)
9.	Fan, Qunfu: 2 articles (01/2015 - 06/2014)
10.	Ye, Wei: 2 articles (01/2015 - 06/2014)

Related Diseases

1.	Alzheimer Disease (Alzheimer's Disease) 01/01/1987 - "On the basis of these clinical and neuropsychological findings, it appears that lecithin alone has no important therapeutic effect in early-onset Alzheimer's disease." 01/01/1990 - "9-Amino-1,2,3,4-tetrahydroaminoacridine (THA) in combination with lecithin has been reported to improve the memory of Alzheimer's disease patients. " 07/01/1991 - "Quantitative EEG during a double-blind trial of THA and lecithin in patients with Alzheimer's disease." 06/01/1987 - "Ten patients with Alzheimer's disease participated in a 26-week double-blind trial of lecithin. " 01/01/1987 - "We conducted a six-month, randomized, double-blind trial of lecithin therapy in early-onset Alzheimer's disease. "
2.	Dementia (Dementias) 01/01/2003 - "To determine the efficacy of lecithin in the treatment of dementia or cognitive impairment. " 01/01/2000 - "To determine the efficacy of lecithin in the treatment of dementia or cognitive impairment. " 01/01/2000 - "To determine the efficacy of lecithin in the treatment of dementia or cognitive impairment. " 01/01/2003 - "Evidence from randomized trials does not support the use of lecithin in the treatment of patients with dementia. " 01/01/2000 - "Evidence from randomized trials does not support the use of lecithin in the treatment of patients with dementia. "
3.	Infection 09/21/1989 - "In patients with few symptoms or when the disease is associated with infection or aspiration, the diagnosis is facilitated by biochemical methods, notably measurement of the lecithin/sphyngomyelin ratio and phosphatidylglycerol assay. " 09/01/1987 - "Mice that had been injected intramuscularly with 100 mg of DHP per kg of body weight, prepared as a microemulsion with lecithin, 1 to 4 days before infection showed enhanced resistance to subcutaneous (s.c.) infection with E. " 06/01/1983 - "An optical density value greater than or equal to 0.15 at A650 n m of amniotic fluid obtained through transabdominal amniocentesis from a high risk obstetrical population, which excluded diabetes mellitus, isoimmunization, and amniotic fluid infection, correlated 98.6% with a mature lecithin to sphingomyelin ratio (L/S) greater than or equal to 2.0% and 41.6% with the presence of phosphatidylglycerol (PG). " 08/01/1983 - "[Growth of acid-fast bacteria enhanced by lecithin given in a form of liposomes: a partial model of mycobacterial infection]." 07/01/1977 - "The nature of changes in cholesterol, general fat and lecithin of chicks' blood is the same as at the infection with a small dose (5000) of oocysts of E. "
4.	Gallstones (Gallstone) 03/01/1976 - "The treatment of patients with gallstones by lecithin." 01/01/1986 - "In order to test whether shock wave fragmentation of human gallstones increases their dissolution rates in a bile acid-lecithin solution, we carried out in vitro experiments. " 07/01/1975 - "Dissolution of human gallstones: the efficacy of bile salt, bile salt plus lecithin and heparin solutions." 08/15/1996 - "Since the composition of biliary lecithins is responsive to dietary manipulations, this study provides new insights into the prevention of cholesterol gallstones." 01/01/2002 - "After 4 weeks, the presence of gallstones or sludge was recorded and bile composition including concentrations of bile acid, cholesterol, lecithin and protein concentrations was studied. "
5.	Body Weight (Weight, Body) 10/01/1981 - "Although the lowest dose produced no changes in fetal viability, body weight or lung weight, a significant reduction in the amount of saturated fatty acid containing lecithin occurred. " 01/01/1990 - "Positive correlations were found to exist between the lecithin/sphingomyelin quotient and body weight gain in the first week of age as well as drinking behaviour of the calves. " 01/01/1983 - "Saturated as well as total lecithins recovered by lung lavage are linearly correlated with the species body weight and with their respiratory rate. " 10/01/1981 - "The treatment resulted in a dose-related increase in prenatal mortality, and decreases in body weight, lung weight and saturated fatty acid containing lecithin content in the fetus but no change in pulmonary sphingomyelin. " 01/01/2009 - "In this case the cause of hemolysis was attributed to the excessive intake of lecithin capsules for the loss of body weight. "

Related Drugs and Biologics

1.	Cholesterol
2.	Choline (Choline Chloride)
3.	Cholinergic Agents (Cholinergics)
4.	Deanol (Dimethylethanolamine)
5.	Liposomes (Liposome)
6.	Tacrine (Cognex)
7.	Phosphatidylcholines (Phosphatidylcholine)
8.	Physostigmine
9.	diclofenac hydroxyethylpyrrolidine (DIEP)
10.	Micelles

Related Therapies and Procedures

1.	Catheters
2.	Fluid Therapy (Oral Rehydration Therapy)
3.	Hypophysectomy
4.	Tocolysis
5.	Radiotherapy