Cytostatic Agents

06/01/1997 - "They are highly effective in restoring cytotoxic activities in immunosuppression induced by tumors and/or cytostatic drugs. "
11/01/2000 - "We believe that resistance modifiers combined with cytostatics will chemotherapeutically be more effective for cancer patients."
09/14/2001 - "The objective of this study is to evaluate a novel approach to chemosensitivity testing with respect to its predictive value in the selection of clinically effective cytostatic drugs to optimize the therapeutic treatment of cancer. "
03/01/2005 - "According to the experimental data obtained drug resistance prophylactics policy is problematically effective in prevention of tumor cells resistance to cytostatics. "
07/01/1985 - "The relative efficacy of rIF in tissue cultures of pancreatic and gastric tumors was further substantiated by the resistance against simultaneously tested single conventional cytostatic drugs. "

07/01/1989 - "These results point to the usefulness of considering the possibility of using radiation energy for the treatment of patients with advanced Hodgkin's disease (phase IIP-IIIP) in whom cytostatic drugs given as a first-line therapy failed to produce complete remission after 4-6 treatment courses, but caused some regression of symptoms with disappearance of systemic signs."
10/15/1969 - "[Varying modification of nucleoside phosphorylation of lymphatic cells by cytostatics effective in Hodgkin's disease]."
01/01/1973 - "[Biological implications of the different efficacy of cytostatics in malignant lymphogranuloma]."
11/01/1996 - "20 patients in early stages (I-IIB) Hodgkin's disease were treated with smaller than commonly used doses of cytostatics and radiation. "
01/01/1989 - "The development of Hodgkin's disease is considered fortuitous and not due to the previous cytostatic drugs."

01/01/1977 - "12 patients affected by acute nonlymphocitic leukemia were treated with cytostatic drugs to induce remission in laminar air flow room. "
01/01/1981 - "[The trials of determination of acute leukemia blasts sensitivity against cytostatics (author's transl)]."
04/14/1980 - "[Study of the blast cell sensitivity to cytostatic agents in acute leukemia by the radioisotope method]."
01/01/2014 - "In fifties, L.Dérer, respecting the mathematical and biological principles in medicine and supported by the mathematician A.Huťa, demonstrated the presence of the "6-day" rhythm in blood leukocyte counts in patients with leukemia, treated by cytostatics. "
10/15/2003 - "Cytoskeletal reorganization during process of apoptosis induced by cytostatic drugs in K-562 and HL-60 leukemia cell lines."

07/08/1966 - "[Model studies on postoperative prevention of metastases by cytostatics]."
06/01/2009 - "In the case of lymph node metastases therapeutic dissection is recommended, in patients with in-transit metastases of the extremities hyperthermic isolated limb perfusion with cytostatic agents may be indicated. "
01/01/2004 - "5 patients out of 15 were treated with cytostatics because of synchronous metastases. "
01/01/2003 - "In patients with distant metastases only low response rates between 10% and 15% have been achieved by the most effective cytostatics in single-agent therapy leading to a mean 5-year survival rate of less than 5%. "
02/01/1991 - "The authors give an account of initial results of surgical removal of metastases in the lungs in seven patients of 48 treated with cytostatics on account of a germinal testicular tumour. "

09/01/2004 - "To extend these promising results, the authors evaluated combinations of 5F11 with conventional cytostatic drugs against a variety of lymphoma cell lines in vitro. "
03/01/2012 - "The rationale for the use of this strategy is the administration of high doses of cytostatics to achieve therapeutic concentrations in sanctuaries, CNS organs and lymphoma tissues and to overcome drug resistance mechanisms. "
03/01/2011 - "RAJI human lymphoma cells were incubated with cytostatics at 37 °C or 42 °C and evaluated for cell culture growth. "
10/01/1993 - "Lesions of the oral mucosa in lymphoma patients receiving cytostatic drugs."
05/01/1980 - "On heterogeneity of non-Hodgkin's lymphomas as regards sensitivity to cytostatic drugs. "