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Takotsubo Cardiomyopathy

A transient left ventricular apical dysfunction or ballooning accompanied by electrocardiographic (ECG) T wave inversions. This abnormality is associated with high levels of CATECHOLAMINES, either administered or endogenously secreted from a tumor or during extreme stress.
Also Known As:
Apical Ballooning Syndrome; Broken Heart Syndrome; Left Ventricular Apical Ballooning Syndrome; Stress Cardiomyopathy; Takotsubo Syndrome; Transient Apical Ballooning Syndrome; Cardiomyopathy, Stress; Cardiomyopathy, Tako-Tsubo; Cardiomyopathy, Takotsubo; Syndrome, Tako-Tsubo; Tako Tsubo Cardiomyopathy; Tako Tsubo Syndrome; Tako-Tsubo Cardiomyopathies; Tako-Tsubo Syndromes; Tako-Tsubo Cardiomyopathy; Tako-Tsubo Syndrome
Networked: 1461 relevant articles (24 outcomes, 65 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Cardiogenic Shock
2. COVID-19
3. Heart Failure
4. Acute Coronary Syndrome
5. Myocardial Stunning (Stunned Myocardium)

Experts

1. Madias, John E: 79 articles (05/2022 - 03/2013)
2. Santoro, Francesco: 24 articles (01/2021 - 08/2012)
3. Brunetti, Natale Daniele: 22 articles (01/2021 - 08/2012)
4. Di Biase, Matteo: 20 articles (01/2021 - 08/2012)
5. Y-Hassan, Shams: 16 articles (11/2021 - 01/2011)
6. Horowitz, John D: 13 articles (10/2020 - 11/2011)
7. Bossone, Eduardo: 12 articles (11/2022 - 05/2008)
8. Borggrefe, Martin: 12 articles (01/2021 - 01/2005)
9. Citro, Rodolfo: 11 articles (11/2022 - 01/2010)
10. Akin, Ibrahim: 11 articles (03/2022 - 01/2014)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Takotsubo Cardiomyopathy:
1. CatecholaminesIBA
2. Biomarkers (Surrogate Marker)IBA
3. TroponinIBA
4. GadoliniumIBA
5. Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
6. Epinephrine (Adrenaline)FDA LinkGeneric
7. Fluorouracil (Carac)FDA LinkGeneric
8. Dopamine (Intropin)FDA LinkGeneric
9. Oxygen (Dioxygen)IBA
07/01/2023 - "Increased oxygen demand, myocarditis, stress cardiomyopathy, elevated pulmonary pressures, and venous thrombosis are potential health issues. "
06/01/2023 - "Cardiac MRI is the modality of choice to differentiate between the different types of myocardial injury such as Takotsubo cardiomyopathy and infection-related cardiomyopathy or even acute coronary syndrome secondary to vasculitis or oxygen-demand mismatch. "
01/01/2020 - "The possible mechanisms of ACS with NONRUPLA are coronary embolism, acute dissection of the aorta or coronary artery, vasospasm, microvascular dysfunction, the imbalance between oxygen demand and supply, coronary trauma and stent complications, direct cellular toxicity and damage, Takotsubo syndrome, and myocardial infarction with non-obstructive coronary arteries (MINOCA)."
09/01/2020 - "The recommendations mainly cover the following aspects: (1) lung ultrasound in patients with COVID-19 is mainly manifested by thickened and irregular pleural lines, different types of B-lines, shred signs, and other consolidation like dynamic air bronchogram; (2) Echocardiography may show right heart dysfunction, diffuse cardiac function enhancement, stress cardiomyopathy, diffuse cardiac depression and other multiple abnormalities; (3) Critical ultrasonography helps with initiating early treatment in the suspect patient, screening confirmed patients after intensive care unit admission, early assessment of sudden critical events, rapid grading assessment and treatment based on it; (4) Critical ultrasonography helps to quickly screen for the etiology of respiratory failure in patients with COVID-19, make oxygen therapeutic strategy, guide the implementation of lung protective ventilation, graded management and precise off-ventilator; (5) Critical ultrasonography is helpful for assessing the circulatory status of patients with COVID-19, finding chronic cardiopulmonary diseases and guiding extracorporeal membrane oxygenation management; (6) Critical ultrasonography contributes to the management of organs besides based on cardiopulmonary oxygen transport; (7) Critical ultrasonography can help to improve the success of operation; (8) Critical ultrasonography can help to improve the safety and quality of nursing; (9) When performing critical ultrasonography for patients with COVID-19, it needs to implement three-level protection standard, pay attention to disinfect the machine and strictly obey the rules from nosocomial infection. "
10. DiureticsIBA

Therapies and Procedures

1. Extracorporeal Membrane Oxygenation
2. Conservative Treatment
3. Therapeutics
4. Liver Transplantation
5. Drug Therapy (Chemotherapy)