rho-Associated Kinases
A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. They were originally found to mediate the effects of rhoA GTP-BINDING PROTEIN on the formation of STRESS FIBERS and FOCAL ADHESIONS. Rho-associated kinases have specificity for a variety of substrates including MYOSIN-LIGHT-CHAIN PHOSPHATASE and LIM KINASES.
Also Known As:
ROCK Protein Kinases; ROCK-I Protein Kinase; ROCK-II Protein Kinase; ROK Kinase; p160 rhoA-Binding Kinase ROKalpha; p160ROCK; rho-Associated Coiled-Coil Containing Protein Kinase 1; rho-Associated Coiled-Coil Containing Protein Kinase 2; rho-Associated Coiled-Coil Kinase; rho-Associated Kinase 1; rho-Associated Kinase 2; rho-Associated Kinase alpha; rho-Associated Kinase beta; rho-Associated Protein Kinase alpha; rho-Associated Protein Kinase beta; rho-Kinase; Coiled-Coil Kinase, rho-Associated; Protein Kinases, ROCK; ROCK I Protein Kinase; ROCK II Protein Kinase; p160 rhoA Binding Kinase ROKalpha; rho Associated Coiled Coil Containing Protein Kinase 1; rho Associated Coiled Coil Containing Protein Kinase 2; rho Associated Coiled Coil Kinase; rho Associated Kinase; rho Associated Kinase 1; rho Associated Kinase 2; rho Associated Kinase alpha; rho Associated Kinase beta; rho Associated Kinases; rho Associated Protein Kinase alpha; rho Associated Protein Kinase beta; rho Kinase; rho-Associated Kinase
Networked: 1279
relevant articles (71 outcomes,
207 trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Experts
1. | Shimokawa, Hiroaki:
69 articles
(10/2015 - 02/2002)
|
2. | Liao, James K:
31 articles
(10/2015 - 07/2002)
|
3. | Kaibuchi, Kozo:
23 articles
(09/2010 - 02/2002)
|
4. | Fukumoto, Yoshihiro:
19 articles
(06/2014 - 01/2004)
|
5. | Takeshita, Akira:
19 articles
(03/2007 - 02/2002)
|
6. | Li, Tao:
16 articles
(05/2015 - 06/2006)
|
7. | Noma, Kensuke:
14 articles
(10/2015 - 05/2003)
|
8. | Webb, R Clinton:
14 articles
(06/2013 - 12/2002)
|
9. | Liu, Liangming:
13 articles
(05/2015 - 06/2005)
|
10. | Shimokawa, H:
13 articles
(10/2007 - 01/2000)
|
Related Diseases
Related Drugs and Biologics
Related Therapies and Procedures