BCR-ABL Negative Atypical Chronic Myeloid Leukemia (Leukemia, Myeloid, Philadelphia Negative)

A myelodysplastic/myeloproliferative disorder characterized by myelodysplasia associated with bone marrow and peripheral blood patterns similar to CHRONIC MYELOID LEUKEMIA, but cytogenetically lacking a PHILADELPHIA CHROMOSOME or bcr/abl fusion gene (GENES, ABL).
Also Known As:
Leukemia, Myeloid, Philadelphia Negative; Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative; Leukemia, Myelogenous, Ph1 Negative; Leukemia, Myelogenous, Ph1-Negative; Leukemia, Myeloid, Chronic, Atypical; Leukemia, Myeloid, Ph1 Negative; Leukemia, Myeloid, Ph1-Negative; Myelogenous Leukemia, Ph1-Negative; Myeloid Leukemia, Ph1-Negative; Leukemia, Ph1-Negative Myelogenous; Leukemia, Ph1-Negative Myeloid; Leukemia, Philadelphia-Negative Myeloid; Leukemias, Ph1-Negative Myelogenous; Leukemias, Ph1-Negative Myeloid; Leukemias, Philadelphia-Negative Myeloid; Myelogenous Leukemia, Ph1 Negative; Myelogenous Leukemias, Ph1-Negative; Myeloid Leukemia, Ph1 Negative; Myeloid Leukemia, Philadelphia Negative; Myeloid Leukemias, Ph1-Negative; Myeloid Leukemias, Philadelphia-Negative; Ph1-Negative Myelogenous Leukemia; Ph1-Negative Myelogenous Leukemias; Ph1-Negative Myeloid Leukemia; Ph1-Negative Myeloid Leukemias; Philadelphia-Negative Myeloid Leukemia; Philadelphia-Negative Myeloid Leukemias; Atypical Chronic Myeloid Leukemia; Chronic Myeloid Leukemia, Atypical; Leukemia, Myeloid, Philadelphia-Negative; Myeloid Leukemia, Philadelphia-Negative
Networked: 56 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Chronic Neutrophilic Leukemia
2. Neoplasms (Cancer)
3. Leukemia
4. Chronic Myelomonocytic Leukemia (Leukemia, Chronic Myelomonocytic)
5. Hematologic Neoplasms (Hematological Malignancy)


1. Tyner, Jeffrey W: 5 articles (01/2020 - 09/2013)
2. Cross, Nicholas C P: 5 articles (09/2010 - 10/2004)
3. Maxson, Julia E: 4 articles (01/2020 - 09/2013)
4. Dao, Kim-Hien T: 3 articles (01/2020 - 01/2014)
5. Druker, Brian J: 3 articles (01/2020 - 01/2014)
6. Gotlib, Jason: 3 articles (01/2020 - 09/2013)
7. Chase, Andrew: 3 articles (09/2010 - 04/2005)
8. Reiter, Andreas: 3 articles (09/2010 - 04/2005)
9. Grand, Francis H: 3 articles (06/2009 - 10/2004)
10. Garcia-Manero, Guillermo: 2 articles (01/2021 - 06/2003)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to BCR-ABL Negative Atypical Chronic Myeloid Leukemia:
1. ruxolitinibIBA
2. Hydroxyurea (Hydrea)FDA LinkGeneric
3. Carrier Proteins (Binding Protein)IBA
4. Imatinib Mesylate (Gleevec)FDA Link
5. DecitabineFDA Link
6. Colony-Stimulating Factors (Colony Stimulating Factor)IBA
7. Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta)IBA
8. Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
9. SteroidsIBA
10. Pyridinolcarbamate (P23)IBA

Therapies and Procedures

1. Hematopoietic Stem Cell Transplantation
2. Transplantation
3. Therapeutics
4. Induction Chemotherapy
5. Stem Cell Transplantation