Myelodysplastic-Myeloproliferative Diseases

Clonal myeloid disorders that possess both dysplastic and proliferative features but are not properly classified as either MYELODYSPLASTIC SYNDROMES or MYELOPROLIFERATIVE DISORDERS.

Also Known As:

Disease, Myelodysplastic-Myeloproliferative; Disease, Myeloproliferative-Myelodisplastic; Diseases, Myelodysplastic-Myeloproliferative; Diseases, Myeloproliferative-Myelodisplastic; Myelodysplastic Myeloproliferative Diseases; Myelodysplastic-Myeloproliferative Disease; Myeloproliferative Myelodisplastic Diseases; Myeloproliferative-Myelodisplastic Disease; Myeloproliferative-Myelodisplastic Diseases

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Hemic and Lymphatic Diseases: 6
- Hematologic Diseases: 3366
  - Bone Marrow Diseases: 135
    - Myelodysplastic-Myeloproliferative Diseases: 7

Related Diseases

1.	Myelodysplastic Syndromes (Myelodysplastic Syndrome)
2.	Leukemia
3.	Primary Myelofibrosis (Myelosclerosis)
4.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
5.	Trisomy (Trisomies)

Experts

1.	Iwai, Fumie: 1 article (01/2022)
2.	Miyakawa, Naoto: 1 article (01/2022)
3.	Nakano, Kazuhisa: 1 article (01/2022)
4.	Ogura-Kato, Aiko: 1 article (01/2022)
5.	Onaka, Takashi: 1 article (01/2022)
6.	Otsuka, Yasuyuki: 1 article (01/2022)
7.	Tanaka, Yoshiya: 1 article (01/2022)
8.	Uemoto, Yuri: 1 article (01/2022)
9.	Yonezawa, Akihito: 1 article (01/2022)
10.	Kovrigina, A M: 1 article (01/2018)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Myelodysplastic-Myeloproliferative Diseases:

1.	AntibodiesIBA 04/01/2002 - "With the ever increasing numbers of antibodies commercially available, the ability to study and understand leukemias, myelodysplastic syndromes, and the myelodysplastic/myeloproliferative diseases is improving. " 01/01/2009 - "By using multiparameter flow cytometry immunophenotypic analysis with antibodies specific for four glycosylphosphatidylinositol-anchored proteins (CD55, CD59, CD16, CD66b) and performing an aerolysin lysis confirmatory test in representative cases, we assessed the paroxysmal nocturnal hemoglobinuria-phenotype granulocytes in 110 patients with myelodysplastic syndrome, 15 with myelodysplastic/myeloproliferative disease, 5 with idiopathic myelofibrosis and 6 with acute myeloid leukemia. "
2.	Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta)IBA 01/01/2018 - "There are new data and general principles of diagnosis of myeloid neoplasms: Ph-negative myeloproliferative diseases, myelodysplastic syndromes, myeloid/lymphoid neoplasms with eosinophilia and rearrangements of PDGFRA, PDGFRB, FGFR1, and PCM1-JAK2, diseases from the group of myelodysplastic/myeloproliferative diseases. "
3.	Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA 01/01/2009 - "By using multiparameter flow cytometry immunophenotypic analysis with antibodies specific for four glycosylphosphatidylinositol-anchored proteins (CD55, CD59, CD16, CD66b) and performing an aerolysin lysis confirmatory test in representative cases, we assessed the paroxysmal nocturnal hemoglobinuria-phenotype granulocytes in 110 patients with myelodysplastic syndrome, 15 with myelodysplastic/myeloproliferative disease, 5 with idiopathic myelofibrosis and 6 with acute myeloid leukemia. "
4.	Pyridinolcarbamate (P23)IBA 10/01/2005 - "We report on a patient fulfilling the diagnostic criteria of unclassifiable myelodysplastic/myeloproliferative diseases with prominent erythropoietic hyperplasia/dysplasia (erythroid preleukemia) and the unique translocation (8;9)(p23;p24). " 10/01/2005 - "Myelodysplastic/myeloproliferative disease with erythropoietic hyperplasia (erythroid preleukemia) and the unique translocation (8;9)(p23;p24): first description of a case." 10/01/2005 - "We report for the first time a myelodysplastic/myeloproliferative disease (erythroid preleukemia) accompanied by the specific chromosomal aberration t(8;9)(p23;p24), distinct histopathology, and clinical and laboratory symptoms, and progress to acute erythroid leukemia."
5.	Proteins (Proteins, Gene)FDA Link 01/01/2009 - "By using multiparameter flow cytometry immunophenotypic analysis with antibodies specific for four glycosylphosphatidylinositol-anchored proteins (CD55, CD59, CD16, CD66b) and performing an aerolysin lysis confirmatory test in representative cases, we assessed the paroxysmal nocturnal hemoglobinuria-phenotype granulocytes in 110 patients with myelodysplastic syndrome, 15 with myelodysplastic/myeloproliferative disease, 5 with idiopathic myelofibrosis and 6 with acute myeloid leukemia. "
6.	aerolysinIBA 01/01/2009 - "By using multiparameter flow cytometry immunophenotypic analysis with antibodies specific for four glycosylphosphatidylinositol-anchored proteins (CD55, CD59, CD16, CD66b) and performing an aerolysin lysis confirmatory test in representative cases, we assessed the paroxysmal nocturnal hemoglobinuria-phenotype granulocytes in 110 patients with myelodysplastic syndrome, 15 with myelodysplastic/myeloproliferative disease, 5 with idiopathic myelofibrosis and 6 with acute myeloid leukemia. "

Therapies and Procedures

1.	Stem Cell Transplantation 01/01/2022 - "Allogeneic stem cell transplantation for trisomy 8-positive myelodysplastic syndrome or myelodysplastic/myeloproliferative disease with refractory Behçet's disease: Case report and the review of literature."
2.	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/01/2010 - "A 33-year-old man with myelodysplastic/myeloproliferative disease underwent allogeneic bone marrow transplantation. "
3.	Splenectomy 06/01/2002 - "Splenectomy in patients with mixed myelodysplastic/myeloproliferative disease."