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Chemokine CCL17

A CC-type chemokine that is found at high levels in the THYMUS and has specificity for CCR4 RECEPTORS. It is synthesized by DENDRITIC CELLS; ENDOTHELIAL CELLS; KERATINOCYTES; and FIBROBLASTS.
Also Known As:
TARC Chemokine; Thymus and Activation-Regulated Chemokine; CCL17, Chemokine; Chemokine, CCL17; Chemokine, TARC; Thymus and Activation Regulated Chemokine; CCL17 Chemokine
Networked: 279 relevant articles (6 outcomes, 23 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Tamaki, Kunihiko: 9 articles (11/2009 - 10/2002)
2. Furue, Masutaka: 8 articles (05/2021 - 09/2007)
3. Kakinuma, Takashi: 6 articles (11/2004 - 10/2002)
4. Nakamura, Koichiro: 6 articles (11/2004 - 10/2002)
5. Matsushima, K: 6 articles (02/2003 - 08/2000)
6. Takeuchi, Satoshi: 5 articles (05/2021 - 04/2012)
7. Saeki, Hidehisa: 5 articles (08/2006 - 10/2002)
8. Wakugawa, Motoshi: 5 articles (11/2004 - 10/2002)
9. Komine, Mayumi: 4 articles (03/2022 - 10/2002)
10. Ichihashi, Ko: 4 articles (01/2022 - 01/2021)

Related Diseases

1. Atopic Dermatitis (Atopic Eczema)
2. Hodgkin Disease (Hodgkin's Disease)
3. Asthma (Bronchial Asthma)
4. Necrosis
08/01/2013 - "Arazyme blocked the secretion of thymus and activation‑regulated chemokine (TARC)/CCL17, MCP‑1, IL‑6 and IL‑8 due to tumor necrosis factor‑α (TNF‑α) and interferon‑γ (IFN‑γ) in HaCaT cells. "
06/15/2018 - "In this study, we report that Lactobacillus strains have a significant suppressive effect on tumour necrosis factor (TNF)-α-induced expression and production of thymus and activation-regulated chemokine (TARC), a T helper 2 cell chemokine responsible for atopic dermatitis, in human keratinocytes. "
06/01/2008 - "The addition of PHF to cultured PBMC reduced supernatant concentrations of brain-derived neurotrophic factor (BDNF), interferon (IFN)-gamma and tumour necrosis factor (TNF)-alpha in response to PHA, and BDNF and thymus and activation-regulated chemokine (TARC) following SEB stimulation. "
02/15/2015 - "Stimulation with tumour necrosis factor-alpha (TNF-α) and interferon-gamma (IFN-γ) caused a significant increase in the production of the following chemokines: thymus- and activation-regulated chemokine (TARC)/CCL17; macrophage-derived chemokine (MDC)/CCL22; regulated on activation, normal T-cell expressed and secreted (RANTES)/CCL5; and interleukin-8 (IL-8) in HaCaT cells. "
05/01/2007 - "The 72-h culture supernatants were analysed by enzyme-linked immunosorbent assay to quantify T helper (Th)1 chemokines (IFN-inducible protein 10 and monokine induced by IFN-gamma), Th2 chemokines [macrophage-derived chemokine (MDC) and thymus and activation-regulated chemokine (TARC)] and proinflammatory cytokines [interleukin (IL)-1alpha and tumour necrosis factor (TNF)-alpha]. "
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. Chemokine CCL22
2. Interleukin-4 (Interleukin 4)
3. Interleukin-13
4. Cytokines
5. Immunoglobulin E (IgE)
6. Proteins (Proteins, Gene)
7. Interleukin-5 (Interleukin 5)
8. Chemokine CCL24
9. Messenger RNA (mRNA)
10. Interleukins

Related Therapies and Procedures

1. Therapeutics
2. Aftercare (After-Treatment)
3. Stem Cell Transplantation
4. Lung Transplantation
5. Peritoneal Dialysis