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Anti-Mullerian Hormone

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A glycoprotein that causes regression of MULLERIAN DUCTS. It is produced by SERTOLI CELLS of the TESTES. In the absence of this hormone, the Mullerian ducts develop into structures of the female reproductive tract. In males, defects of this hormone result in persistent Mullerian duct, a form of MALE PSEUDOHERMAPHRODITISM.

Also Known As:

Anti-Mullerian Factor; Antimullerian Hormone; Mullerian Inhibiting Hormone; Mullerian Inhibiting Substance; Mullerian Regression Factor; Mullerian-Inhibiting Factor; Mullerian-Inhibitory Substance; Anti Mullerian Factor; Anti Mullerian Hormone; Mullerian Inhibiting Factor; Mullerian Inhibitory Substance; Mullerian-Inhibiting Hormone; Muellerian Inhibiting Hormone

Networked: 214 relevant articles (1 outcomes, 28 trials/studies)

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Bio-Agent Context: Research Results

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 60571
  - Gonadal Hormones: 363
    - Testicular Hormones: 15
      - Anti-Mullerian Hormone: 214

Experts

1.	Donahoe, Patricia K: 15 articles (08/2015 - 08/2002)
2.	MacLaughlin, David T: 13 articles (09/2012 - 01/2002)
3.	Pieretti-Vanmarcke, Rafael: 5 articles (01/2011 - 03/2006)
4.	Maheswaran, Shyamala: 5 articles (03/2007 - 12/2003)
5.	Chang, R Jeffrey: 4 articles (01/2015 - 05/2007)
6.	Sahmay, Sezai: 4 articles (07/2014 - 09/2012)
7.	Eldar-Geva, Talia: 4 articles (05/2014 - 07/2005)
8.	Sammel, Mary D: 4 articles (03/2014 - 01/2007)
9.	Gracia, Clarisa R: 4 articles (03/2014 - 01/2007)
10.	Gupta, Vandana: 4 articles (03/2007 - 12/2003)

Related Diseases

1.	Endometriosis (Adenomyosis) 01/01/2015 - "Serum antimullerian hormone (AMH) proposed to be a reliable marker of ovarian reserve; the aim of this study was to evaluate the influence and value of laparoscopic management in endometriosis as measured by serum AMH levels. " 01/01/2014 - "The aim of this study was to measure anti-Mullerian hormone (AMH) serum levels in women with severe endometriosis, in order to demonstrate the effect of the disease on ovarian reserve. " 01/01/2013 - "To determine the effects of Mullerian inhibiting substance (MIS) treatment on endometriosis cells through study of apoptosis and autophagy. " 01/01/2015 - "Age-related trends in anti-Mullerian hormone serum level in women with unilateral and bilateral ovarian endometriomas prior to surgery." 01/01/2015 - "Evaluation of antimullerian hormone levels before and after laparoscopic management of endometriosis."
2.	Pelvic Pain 12/01/2015 - "Surgical excision is more effective than fenestration/coagulation of endometrioma for pelvic pain but decreases antimullerian hormone. "
3.	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 12/01/2015 - "The aim of the study was to investigate the presence of possible markers in the prediction of polycystic ovary syndrome (PCOS)-related metabolic alterations and cardiovascular events in adolescent PCOS cases and also to investigate the applicability of anti-Mullerian hormone (AMH) levels for the diagnosis of PCOS. " 11/01/2014 - "This study aimed to [1] confirm that nonobese adolescents with polycystic ovary syndrome (PCOS) have higher anti-Mullerian hormone (AMH) than controls; [2] examine the relationship of AMH with PCOS features and hormonal profile; and [3] approximate an AMH value that discriminates between adolescents with PCOS and controls. " 01/01/2011 - "This study aimed to assess the relationship between the serum levels of anti-mullerian hormone (AMH) and other hormonal markers and results of assisted reproductive techniques (ART) in polycystic ovary syndrome (PCOS) patients. " 10/01/2004 - "The aim of the present study was to examine the relationship between Mullerian-inhibiting substance (MIS) levels and metabolic characteristics in women with polycystic ovary syndrome. " 11/01/2015 - "Can anti-Mullerian hormone replace ultrasonographic evaluation in polycystic ovary syndrome? "
4.	Neoplasms (Cancer) 01/01/2011 - "Mullerian inhibiting substance inhibits invasion and migration of epithelial cancer cell lines." 03/01/2007 - "Mullerian Inhibiting Substance (MIS) has been evaluated for its inhibitory effects in cancers of the reproductive tissues and is in development as an anti-cancer drug. " 12/23/2003 - "Mullerian Inhibiting Substance inhibits cervical cancer cell growth via a pathway involving p130 and p107." 03/15/2003 - "We report that female transgenic mice expressing the transforming region of SV40 under control of the Mullerian inhibitory substance type II receptor gene promoter develop bilateral ovarian tumors in approximately 50% of cases. " 03/01/1992 - "Since Mullerian Inhibiting Substance (MIS) causes regression of the Mullerian duct, the anlagen of the uterus, vagina, and fallopian tube, we expected and have previously observed that purified recombinant human MIS causes regression of gynecological tumors. "
5.	Infertility (Sterility) 10/01/2015 - "Use of anti-mullerian hormone for testing ovarian reserve: a survey of 796 infertility clinics worldwide." 08/01/2015 - "Based on a random-effects meta-analysis, significant association between infertility (RR = 1.28, 95% CI = 1.16-1.42), acute ovarian failure (AOF) (RR = 9.51, 95% CI = 5.03-17.96), low level of anti mullerian hormone (AMH) (<1 ng/mL) (RR = 14.79, 95% CI = 3.36-66.64), stillbirth (RR = 1.19, 95% CI = 1.02-1.39) and low birth weight (RR = 2.22, 95% CI = 1.55-3.17) were identified. " 06/01/2014 - "Predictive factors for pregnancy were anti-mullerian hormone in the group undergoing IUI treatment and in the age group ≥38-duration of infertility. " 03/01/2013 - "At the time of the consultation in a second-level infertility centre, most of the female patients had already been examined for ovarian, hypophyseal and thyroid function, but only 12% had undergone an anti-Mullerian hormone (AMH) determination: 56% had microbiological culture performed. " 09/01/2012 - "Serum anti-mullerian hormone levels of women younger than 45 years admitted to our reproductive endocrinology clinic for investigation of infertility were examined in this cross-sectional study. "

Related Drugs and Biologics

1.	inhibin B
2.	Follicle Stimulating Hormone (Follitropin)
3.	Antral
4.	anti-Mullerian hormone receptor
5.	Testosterone (Sustanon)
6.	Insulin (Novolin)
7.	Messenger RNA (mRNA)
8.	Insulin-Like Growth Factor I (IGF-1)
9.	Cyclin-Dependent Kinase 4
10.	Cyclin D1

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Cystectomy
3.	Heterologous Transplantation (Xenotransplantation)
4.	Transplantation (Transplant Recipients)
5.	Radiotherapy