Interleukin-10 Receptor alpha Subunit

A subunit of the interleukin-10 receptor. It plays a role in receptor signaling by associating with JANUS KINASE 1.

Also Known As:

IL-10R1 Receptor; Interleukin-10 Receptor 1; IL 10R1 Receptor; Interleukin 10 Receptor 1; Interleukin 10 Receptor alpha Chain; Interleukin 10 Receptor alpha Subunit; Receptor, IL-10R1; Antigens, CDW210A; CDW210A Antigens; Interleukin-10 Receptor alpha Chain

Networked: 10 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Immunologic Receptors: 9
        Cytokine Receptors: 1620
        Interleukin Receptors: 114
        Interleukin-10 Receptors: 227
        Interleukin-10 Receptor alpha Subunit: 10

Experts

1.	Gasche, Christoph: 2 articles (01/2008 - 04/2007)
2.	Hornik, Kurt: 2 articles (01/2008 - 04/2007)
3.	Leisch, Friedrich: 2 articles (01/2008 - 04/2007)
4.	Schloegelhofer, Monika: 2 articles (01/2008 - 04/2007)
5.	Schosser, Alexandra: 2 articles (01/2008 - 04/2007)
6.	Chen, Xiao-Yan: 1 article (11/2021)
7.	Deng, Xing: 1 article (11/2021)
8.	Huang, Jie-Bin: 1 article (11/2021)
9.	Lv, Jia-Jia: 1 article (11/2021)
10.	Su, Wen: 1 article (11/2021)

Related Diseases

1.	Leishmaniasis 01/01/2020 - "In this study, recombinant canine cytokines (rcaIL-12, rcaIL-2, rcaIL-15 and rcaIL-7) and soluble receptor IL-10R1 (rcasIL-10R1), with antagonistic activity, were evaluated for the first time in combination (rcaIL-12/rcaIL-2, rcaIL-12/rcaIL-15, rcaIL-12/rcasIL-10R1, rcaIL-15/rcaIL-7) or alone (rcasIL-10R1) to evaluate their immunomodulatory capacity in peripheral blood mononuclear cells (PBMCs) from dogs with leishmaniasis. "
2.	Adenomyosis 04/01/2012 - "To investigate the expression and potential roles of interleukin-10 receptor 1 (IL-10R1) and interleukin-10 receptor 2 (IL-10R2) in adenomyosis. "
3.	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 11/28/2021 - "Interleukin 10 receptor alpha subunit (IL10RA) dysfunction is the main cause of very early-onset inflammatory bowel disease (VEO-IBD) in East Asians. " 11/28/2021 - "Autosomal recessive 333 base pair interleukin 10 receptor alpha subunit deletion in very early-onset inflammatory bowel disease."
4.	Virus Diseases (Viral Diseases) 08/04/2023 - "The number of patients showing infiltrating lesions was higher, the number of smokers was lower, and CD severity was worse in patients in subgroup II than those in subgroup I. The specific genes relevant to subgroup II included cluster of differentiation 44, tryptophanyl-tRNA synthetase, and interleukin 10 receptor, alpha subunit, which may be related to viral infection. "
5.	Schizophrenia (Dementia Praecox) 04/05/2007 - "Homozygosity of the interleukin-10 receptor 1 G330R allele is associated with schizophrenia."

Related Drugs and Biologics

1.	Cytokines
2.	Interleukin-10 Receptor beta Subunit (Interleukin-10 Receptor 2)
3.	Tryptophan-tRNA Ligase
4.	Ribavirin (Virazole)
5.	Interferons

Related Therapies and Procedures

1.	Therapeutics