Interleukin-5 Receptor alpha Subunit

A low affinity interleukin-5 receptor subunit that combines with the CYTOKINE RECEPTOR COMMON BETA SUBUNIT to form a high affinity receptor for INTERLEUKIN-5. Several isoforms of the interleukin-5 receptor alpha subunit exist due to multiple ALTERNATIVE SPLICING.

Also Known As:

CD125 Antigen; Interleukin-5 Receptor alpha Chain; Receptor, Interleukin-5, alpha Subunit; alpha-Subunit, Receptor, Interleukin-5; Antigen, CD125; Interleukin 5 Receptor alpha Chain; Interleukin 5 Receptor alpha Subunit; Antigens, CD125; CD125 Antigens

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Immunologic Receptors: 9
        Cytokine Receptors: 1620
        Interleukin Receptors: 114
        Interleukin-5 Receptors: 134
        Interleukin-5 Receptor alpha Subunit: 4
        human IL5RA protein
        mouse interleukin-5- receptor alpha

Experts

1.	Baum, Larry: 1 article (03/2011)
2.	Chan, Juliana C N: 1 article (03/2011)
3.	Lam, Vincent: 1 article (03/2011)
4.	Luk, Andrea O Y: 1 article (03/2011)
5.	Ma, Ronald C W: 1 article (03/2011)
6.	Ng, Maggie C Y: 1 article (03/2011)
7.	So, Wing-Yee: 1 article (03/2011)
8.	Tam, Claudia H T: 1 article (03/2011)
9.	Tong, Peter C Y: 1 article (03/2011)
10.	Wang, Ying: 1 article (03/2011)

Related Diseases

1.	Inflammation (Inflammations) 06/01/2000 - "Allergen-induced airway inflammation and bronchial responsiveness in interleukin-5 receptor alpha chain-deficient mice."
2.	Eosinophilia 01/01/1997 - "Eosinophilia and intracranial worm recovery in interleukin-5 transgenic and interleukin-5 receptor alpha chain-knockout mice infected with Angiostrongylus cantonensis."
3.	Type 2 Diabetes Mellitus (MODY) 03/01/2011 - "Predictive role of polymorphisms in interleukin-5 receptor alpha-subunit, lipoprotein lipase, integrin A2 and nitric oxide synthase genes on ischemic stroke in type 2 diabetes--an 8-year prospective cohort analysis of 1327 Chinese patients."
4.	Asthma (Bronchial Asthma) 01/01/2005 - "Association analysis of interleukin 5 receptor alpha subunit (IL5RA) polymorphisms and asthma."
5.	Ischemic Stroke 03/01/2011 - "Predictive role of polymorphisms in interleukin-5 receptor alpha-subunit, lipoprotein lipase, integrin A2 and nitric oxide synthase genes on ischemic stroke in type 2 diabetes--an 8-year prospective cohort analysis of 1327 Chinese patients."

Related Drugs and Biologics

1.	Nitric Oxide Synthase (NO Synthase)
2.	Integrins
3.	Interleukin-5 (Interleukin 5)
4.	Lipoprotein Lipase (Diacylglycerol Lipase)
5.	Allergens