Interferon alpha-beta Receptor (Receptor, Interferon alpha beta)

A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE.
Also Known As:
Receptor, Interferon alpha beta; Receptor, Interferon alpha-beta; IFN-alphaR; IFN-alphabetaR; IFNAR1 Subunit, Interferon alpha-beta Receptor; IFNAR2 Subunit, Interferon alpha-beta Receptor; IFNAR2.1 Subunit, Interferon alpha-beta Receptor; IFNAR2.2 Subunit, Interferon alpha-beta Receptor; Interferon alpha Receptor; Interferon alpha Receptors; Interferon alpha-beta Receptor Chain 1; Interferon alpha-beta Receptor Chain 2; Interferon alpha-beta Receptor IFNAR1 Subunit; Interferon alpha-beta Receptor IFNAR2 Subunit; Interferon alpha-beta Receptor-1; Interferon alpha-beta Receptor-2; Interferon alphabeta Receptors; Receptor, Interferon alpha; Type I Interferon Receptor; IFN alphabetaR; IFNAR1 Subunit, Interferon alpha beta Receptor; IFNAR2 Subunit, Interferon alpha beta Receptor; IFNAR2.1 Subunit, Interferon alpha beta Receptor; IFNAR2.2 Subunit, Interferon alpha beta Receptor; Interferon alpha beta Receptor; Interferon alpha beta Receptor 1; Interferon alpha beta Receptor 2; Interferon alpha beta Receptor Chain 1; Interferon alpha beta Receptor Chain 2; Interferon alpha beta Receptor IFNAR1 Subunit; Interferon alpha beta Receptor IFNAR2 Subunit; Receptor-1, Interferon alpha-beta; Receptor-2, Interferon alpha-beta; Receptors, Interferon alpha; Receptors, Interferon alphabeta; alpha Receptor, Interferon; alpha Receptors, Interferon; alpha-beta Receptor-1, Interferon; alpha-beta Receptor-2, Interferon
Networked: 130 relevant articles (5 outcomes, 10 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Calvo-Pinilla, Eva: 4 articles (04/2015 - 11/2010)
2. Kalinke, Ulrich: 4 articles (03/2015 - 11/2006)
3. Ortego, Javier: 3 articles (04/2015 - 11/2010)
4. Castillo-Olivares, Javier: 3 articles (04/2015 - 02/2014)
5. Gubbins, Simon: 3 articles (04/2015 - 02/2014)
6. Yanai, Yoshiaki: 3 articles (06/2011 - 01/2007)
7. Mertens, Peter Paul Clement: 2 articles (04/2015 - 02/2014)
8. de la Poza, Francisco: 2 articles (04/2015 - 02/2014)
9. Volz, Asisa: 2 articles (09/2014 - 04/2011)
10. Sutter, Gerd: 2 articles (09/2014 - 04/2011)

Related Diseases

1. Chronic Hepatitis C
2. Renal Cell Carcinoma (Grawitz Tumor)
3. Multiple Sclerosis
4. Fibrosis (Cirrhosis)
5. Bacterial Infections (Bacterial Infection)

Related Drugs and Biologics

1. Interferons
2. Messenger RNA (mRNA)
3. Interferon-alpha (Interferon Alfa)
4. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
5. Transforming Growth Factor beta1 (TGF beta 1)
6. Interleukin-7 Receptor alpha Subunit
7. Interleukin-17 (Interleukin 27)
8. CCR5 Receptors (CCR5 Receptor)
9. Histocompatibility Antigens (Histocompatibility Antigen)
10. sorafenib (BAY 43-9006)

Related Therapies and Procedures

1. Immunotherapy
2. Transplantation (Transplant Recipients)