Hypercalciuria

08/01/1984 - "Low calcium diet combined with hydrochlorthiazide was the most effective treatment for hypercalciuria. "
10/01/1978 - "A steep slope of calcium excretion on calcium intake (due to increased calcium absorption) was noted in all hypercalciuric patients and accounted for the significantly improved diagnostic accuracy of screening patients for hypercalciuria on the high-normal calcium intake. "
01/10/2002 - "A low-calcium diet is recommended to prevent recurrent stones in patients with idiopathic hypercalciuria, yet long-term data on the efficacy of a low-calcium diet are lacking. "
01/01/2018 - "The use of ICaCre index for determining calcium urine excretion might be effective in the study of hypercalciuria associated with NGH and RL. "
05/01/2003 - "Moderate calcium restriction is only effective in absorptive hypercalciuria. "

04/01/2015 - "We also demonstrate the efficacy of a treatment with thiazides in terms of hypercalciuria in the majority of patients."
11/01/1984 - "[Contribution of thiazides to the study of idiopathic hypercalciuria]."
04/01/2015 - "Treatment with thiazides effectively reduced hypercalciuria in most cases. "
08/15/2013 - "Role of proximal tubule in the hypocalciuric response to thiazide of patients with idiopathic hypercalciuria."
02/01/2013 - "Under a high-Na+ diet, KO mice exhibited hypercalciuria and increased blood pressure, which were reversed by thiazide treatment. "

08/01/2011 - "Our results suggest that low dose (0.5 mg/kg/day) of hydrochlorothiazide may be safe and effective in controlling renal hypercalciuria in children."
12/01/2013 - "Since hydrochlorothiazide ameliorates hypercalciuria, we assessed its efficacy in preventing recurrent UTIs in hypercalciuric girls. "
11/01/2023 - "Current guidelines preserve the use of hydrochlorothiazide to patients with overt hypercalciuria, while NOSTONE also included patients without hypercalciuria. "
01/01/2012 - "Low-dose or high-dose hydrochlorothiazide in idiopathic hypercalciuria among children? "
07/01/1999 - "After two years on continuous treatment with hydrochlorothiazide, hypercalciuria decreased without deterioration of renal function. "

06/01/2009 - "This study demonstrated that the renal phosphate reabsorption capacity was significantly decreased in stone formers compared to normal controls, and that a low maximal reabsorption of phosphate by the glomerular filtration rate was associated with hypercalciuria and hyperuricosuria. "
05/01/1990 - "However, correction of these data according to the male to female ratio of our study population revealed renal hypercalciuria to be more prevalent in females whereas absorptive hypercalciuria and hypercalciuria from loss of renal phosphates were more prevalent in men. "
06/01/2022 - "Genetic renal phosphate leak is one of the rare disorders in recurrent stone formers with absorptive hypercalciuria. "
10/18/2019 - "Renal phosphate excretion was normal whereas mild hypercalciuria was found. "
01/01/2014 - "Orally administered inorganic phosphate is predicted to improve symptoms in these patients, hence screening for SLC34A3 mutations should be considered in patients with hypercalciuria of unknown etiology."

01/01/2022 - "An inverse relationship between Uca/Ucr ratio and 25-OH-D3 level was noted, which means that vitamin D supplementation is helpful for preventing hypercalciuria related to KDT. "
12/08/2020 - "As regards adverse events, higher-dose vitamin D supplementation may make little to no difference in developing hypercalciuria (RR 1.16, 95% CI 1.00 to 1.35; 6 studies, 554 participants; low-certainty evidence) or in hypercalcaemia (RR 1.39, 95% CI 0.89 to 2.18; 5 studies, 986 participants; low-certainty evidence) compared to lower-dose vitamin D supplementation. "
12/08/2020 - "In terms of adverse events, vitamin D supplementation results in little to no difference in developing hypercalciuria compared to placebo (RR 2.03, 95% CI 0.28 to 14.67; 2 studies, 68 participants; high-certainty evidence). "
01/01/2019 - "The aim of the present study was to determine whether use of vitamin D supplementation might increase the risk of hypercalciuria. "
10/01/2016 - "Similar increased risk of hypercalciuria was shown in 14 studies for the vitamin D group (RR: 1.64; 95% CI: 1.06, 2.53; P = 0.03). "

05/01/2004 - "A crossover, acute-load study was designed to investigate whether processed fruit was as effective as fresh fruit in reducing NAE and protein-induced hypercalciuria. "
06/01/1989 - "Various studies have shown that a high protein (HP) diet, compared to a low protein (LP) diet, leads to hypercalciuria and alterations in renal and systemic hemodynamics. "
06/01/1983 - "Previous studies in this Unit have shown that a high protein intake, given as meat, did not induce hypercalciuria, except for the initial and temporary increase in two subjects. "
02/01/1980 - "Studies on the mechanism of protein-induced hypercalciuria in older men and women."
04/01/1979 - "Protein-induced hypercalciuria: a longer term study."

01/10/2002 - "We conducted a five-year randomized trial comparing the effect of two diets in 120 men with recurrent calcium oxalate stones and hypercalciuria. "
09/01/2000 - "This study defines to what extent hypercalciuria represents a risk factor for recurrent calcium oxalate or nonstruvite stones. "
09/01/2021 - "Calcium oxalate (Ca-Ox) is the most common stone composition and one of the most common 24-h urine anomalies is hypercalciuria. "
11/01/2018 - "In recurrent stone formers with hypercalciuria baseline values and changes in the relative supersaturation of calcium oxalate may be associated with the risk of recurrence. "
11/01/2018 - "We performed a post hoc analysis of data from a previously published randomized controlled trial comparing the effect of 2 diets in 120 men with recurrent calcium oxalate stones and hypercalciuria. "

01/01/2012 - "Similar to other studies in Iran this study shows that the prevalence of hypercalciuria is significantly higher comparing to other countries, it may be associated with excessive intake of sodium."
02/01/1996 - "Children who were normocalciuric at the second study had significantly lower values of urine sodium excretion when compared with those in whom hypercalciuria persisted. "
01/01/2015 - "Urinary sodium was significantly higher in patients with hypercalciuria than without (246.97 ± 103.9 mEq/24 h vs. 200.31 ± 91.6 mEq/24 h, p = 0.001) and hyperuricosuria compared to without (283.24 ± 107.95 mEq/24 h vs. 198.57 ± 85.3 mEq/24 h, p = 0.001). "
04/01/2014 - "Moreover, high sodium excretion was more frequent in men than women (59.2% vs 49.3%, P = .027), whereas hypercalciuria was more common in women (34.5% vs 20.4%, P <.001). "
08/01/2009 - "Hypercalciuria in FHHt seems to be dependent on urinary sodium. "

01/01/2017 - "Future studies should analyse if manipulating the renal kallikrein-kinin system can correct idiopathic hypercalciuria with drugs other than thiazide diuretics."
03/01/2013 - "It is especially important to consider Cr/kg when there is potential for undertreatment or overtreatment of patients with abnormal Cr/kg. Studies demonstrating hypercalciuria and high Cr/kg may need to be repeated before starting thiazide diuretics. "
11/11/2022 - "Thiazide diuretics can be used to reduce hypercalciuria in some cases. "
07/25/2021 - "In patients with sustained hypercalciuria, a thiazide diuretic was prescribed. "
08/01/2011 - "Low-dose thiazide diuretics in children with idiopathic renal hypercalciuria."

03/01/2020 - "Urinalyses of the parents revealed that the father had acidic hypocitraturic urine, containing oxalate crystals, and the mother had hypercalciuria. "
02/01/2011 - "Little is known about the renal handling of oxalate in patients with idiopathic hypercalciuria (IH). "
02/01/2003 - "Since hypercalciuria is of much less importance than increases in urinary oxalate, therapeutic efforts should primarily focus on lowering urinary oxalate excretion. "
04/01/1989 - "This mild hypercalciuria was interpreted as being secondary to both a higher intake and increased fractional intestinal absorption of oxalate. "
07/01/1984 - "Oxalate absorption and postprandial urine supersaturation in an experimental human model of absorptive hypercalciuria."

01/01/1994 - "For each form of hypercalciuria, selective therapy should provide the best results."
10/01/1984 - "However, only 48 per cent of the normocalciuric patients were in remission after 5 years of high fluid intake therapy and 45 per cent of those with absorptive hypercalciuria were free of recurrence with diet only. "
03/01/1991 - "Although rice bran therapy should be effective in correcting absorptive hypercalciuria, there may be limits to the overall ability of rice bran monotherapy to prevent recurrence."
01/01/2022 - "Further study is needed to determine the causes of hypercalciuria in pediatric patients and develop targeted therapies. "
01/01/2014 - "Descriptive study of clinical profile and benefit of therapy in childhood hypercalciuria."

10/01/2017 - "After treatment, a decrease in the frequency of hypercalciuria and hypocitraturia was observed, just like the urinary saturation risk for all types of crystals studied. "
04/01/1989 - "Twenty-seven normocalcemic patients aged 11-69 yrs with recurrent renal stone formation and idiopathic hypercalciuria were studied before and after treatment with hydrochlorthiazide (TD) 50 mg twice a day for 6 months. "
07/01/1996 - "Remission of hypercalciuria in patients with tuberculosis after treatment."
01/01/1992 - "After treatment, metabolic acidosis and hypercalciuria improved, and the patient had a catch-up growth phase. "
07/01/1996 - "The hypercalciuria evolution and other bone metabolism parameters were evaluated in patients with tuberculosis after treatment. "

11/01/2011 - "Dietary modifications alone do not improve bone mineral density in children with idiopathic hypercalciuria."
04/01/2009 - "Dietary modifications are often sufficient in the management of hypercalciuria. "
11/01/2005 - "Changes produced by dietary modification from the random diet were evaluated in 356 patients with moderate-severe hypercalciuria (>6.88 mmol/day, group I), 243 patients with mild hypercalciuria (5.00-6.88 mmol/day, group II), and 352 with normocalciuria (<5.00 mmol/day, group III). "
08/01/2004 - "Diet modification should be done according to the various metabolic factors contributing to the formation of the stone (ie, hypercalciuria, hyperoxaluria, hypocitraturia, hyperuricuria, and so forth). "
01/01/2004 - "The results suggest that hypercalciuria and hyperoxaluria contribute to the formation of CaOx uroliths in dogs and show that dietary modifications can alter this process."

08/01/2021 - "Forty-nine out of the 55 ALL patients exhibited hypercalciuria at least once during chemotherapy. "
02/01/2011 - "In terms of pharmacotherapy, there are drugs to successfully improve hypercalciuria, hypocitraturia, aciduria, hyperuricosuria, and hypercystinuria. "
03/01/1996 - "In cases of hypercalciuria it is suitable to prescribe adjuvant specific diets or drug therapy."
12/01/1994 - "Following completion of the chemotherapy, hypercalcaemia and hypercalciuria returned with levels similar to those observed pretreatment. "
05/01/1990 - "Their hypercalciuria was difficult to manage and required frequent manipulations of drug therapy and diet restrictions. "

01/01/2021 - "Persistent hypercalciuria after parathyroidectomy."
10/01/2020 - "Parathyroidectomy reduces 24-hour UCa excretion in the majority of patients with PHPT and restores normocalciuria in 79% of patients with hypercalciuria at baseline."
05/01/2020 - "Overall, 150 patients had an indication for surgery; of them, the 29 who underwent parathyroidectomy were younger than the non-operated patients and had higher rates of hypercalciuria. "
01/01/2020 - "The latest guidelines suggest parathyroidectomy in patients with asymptomatic PHPT with hypercalciuria (> 400 mg/d) and increased stone risk profile. "
01/01/2020 - "However, 37 of 69 patients (54%) had persistent hypercalciuria postoperatively, and 16 of 69 (23%) had recurrent KSD, on average, 2.0 ± 1.6 years after parathyroidectomy. "