Keratin-8 (Keratin 8)

03/01/2007 - "Immunohistochemical studies on cytokeratin 8 and 18 expressions in canine cutaneous adnexus and their tumors."
12/01/2015 - "Brush biopsies of 30 subsequently histologically-confirmed oral/oropharyngo-/laryngeal cavity cancer cases (all then in a recurrence status) and normal mucosa were obtained for routine cytology and immunocytology for cytokeratin-8 (CK-8). "
08/01/2014 - "The association of high EGFR and low cytokeratin 8/18 expression in tumor cells on one hand and high density of CD8+ tumor-infiltrating lymphocytes on the other hand were significantly predictive of pCR. "
12/01/2013 - "Because upregulation of RPSA and dephosphorylation of cytokeratins 8/18 have been linked with tumor progression, these data suggest that parkin may inhibit cell growth, at least in part, by decreasing RPSA expression and inducing phosphorylation of cytokeratin 8/18."
12/01/2011 - "Use of cytokeratin 8 immunohistochemistry for assessing cell death after radiofrequency ablation of breast cancers."

05/01/2010 - "Although CAM 5.2 has been reported to be helpful in distinguishing between primary endocervical adenocarcinomas and endometrial adenocarcinomas, we could not verify this point of view using the true cytokeratin 8/18 monoclonal antibody (Leica Microsystems). "
05/01/2010 - "The purpose of this study was to make clear whether the immunohistochemistry of the true cytokeratin 8/18 monoclonal antibody (Leica Microsystems, Newcastle, United Kingdom), instead of CAM 5.2 (Becton Dickinson Biosciences, San Jose, CA), has potential use in distinguishing between endocervical adenocarcinomas and endometrial adenocarcinomas. "
05/01/2010 - "True cytokeratin 8/18 immunohistochemistry is of no use in distinguishing between primary endocervical and endometrial adenocarcinomas in a tissue microarray study."
05/01/2010 - "In conclusion, the true cytokeratin 8/18 monoclonal antibody is of no use in distinguishing between primary endocervical adenocarcinomas and endometrial adenocarcinomas."
07/01/2001 - "We reported previously that adenocarcinoma-reactive human monoclonal antibody AE6F4, which had been generated by in vitro immunization method, recognizes both 14-3-3protein and cytokeratin 8 (CK8). "

11/01/2011 - "The immunohistochemical study of proliferation and intermediate filament--keratin 8 expressions at oral hyperkeratosis and oral Squamous cell carcinoma (OSCC) has been carried out. "
11/01/2011 - "[Keratin 8 expression in mouth mucosa hyperkeratosis and squamous cell carcinoma ]."
08/27/2010 - "Ectopic coexpression of keratin 8 and 18 promotes invasion of transformed keratinocytes and is induced in patients with cutaneous squamous cell carcinoma."
01/01/2006 - "Cytokeratin 8/18 expression indicates a poor prognosis in squamous cell carcinomas of the oral cavity."
05/01/1997 - "Tumour cells expressed cytokeratin 8 and were arranged in a pattern similar to that of a squamous cell carcinoma found elsewhere, with prickle cells and horny pearls. "

05/01/2006 - "In a previous study, the authors have shown cytokeratin 8 (CK8) and epitope H ultrastructural localization in breast cancer cell nuclei. "
01/01/2013 - "Identification of a mimotope for circulating anti-cytokeratin 8/18 antibody and its usage for the diagnosis of breast cancer."
06/01/2010 - "Autophagy regulates keratin 8 homeostasis in mammary epithelial cells and in breast tumors."
04/01/2009 - "low levels of SMAR1 correlating with high expression of Cytokeratin 8) in higher grades of breast cancer. "
01/01/2008 - "Relevance of the immunohistochemical expression of cytokeratin 8/18 for the diagnosis and classification of breast cancer."

01/01/2010 - "Protein-protein interaction (PPI) analysis indicated that 14-3-3sigma/EGFR/keratin 8 interactions may be involved in the invasion and metastasis of NPC. "
05/01/2004 - "Compared with immunohistochemical staining for cytokeratin 8, which detected metastases in 17 of 42 patients, reverse transcription-polymerase chain reaction (RT-PCR) for MGB1 or MGB2 genes was positive in 22 patients. "
05/01/2015 - "In stage II/III lymph node-positive breast cancer patients less than 55 years of age, keratin 8 expression in lymph node metastases but not in the primary tumour is an indicator of better survival."
01/01/2008 - "We examined the association of DTC detection (cytokeratin 8, 18 or 19 positive epithelial cells with cancerous morphological features), at metastatic relapse, with the metastasis-free interval in breast cancer patients. "
10/01/2002 - "The routine examination has detected axillary lymph nodes metastases in six cases, confirmed by the immunohistochemistry for cytokeratin 8. Four cases were diagnosed as negative for the axillary lymph nodes metastases by the hematoxilin-eosin staining. "