HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Apolipoprotein C-III

A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS and CHYLOMICRON REMNANTS. Apo C-III, synthesized in the liver, is an inhibitor of LIPOPROTEIN LIPASE. Apo C-III modulates the binding of chylomicron remnants and VLDL to receptors (RECEPTORS, LDL) thus decreases the uptake of triglyceride-rich particles by the liver cells and subsequent degradation. The normal Apo C-III is glycosylated. There are several polymorphic forms with varying amounts of SIALIC ACID (Apo C-III-0, Apo C-III-1, and Apo C-III-2).
Also Known As:
Apo C-III; Apo C-III-2; ApoC-III; Apolipoprotein C-III-0; Apolipoprotein C-III-1; Apolipoprotein CIII; Sialyl Apo C-III; Sialyl Apolipoprotein C-III; Apo C III; Apo C III 2; Apo C-III, Sialyl; ApoC III; Apolipoprotein C III; Apolipoprotein C III 0; Apolipoprotein C III 1; Apolipoprotein C-III, Sialyl; Sialyl Apo C III; Sialyl Apolipoprotein C III
Networked: 542 relevant articles (23 outcomes, 75 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Sacks, Frank M: 24 articles (12/2021 - 04/2003)
2. Chan, Dick C: 13 articles (12/2021 - 08/2002)
3. Watts, Gerald F: 13 articles (12/2021 - 08/2002)
4. Furtado, Jeremy D: 12 articles (01/2021 - 04/2012)
5. Barrett, P Hugh R: 12 articles (10/2015 - 08/2002)
6. Jensen, Majken K: 11 articles (01/2021 - 04/2012)
7. Taskinen, Marja-Riitta: 10 articles (01/2022 - 06/2005)
8. Olivieri, Oliviero: 9 articles (01/2021 - 09/2002)
9. Witztum, Joseph L: 8 articles (01/2022 - 07/2015)
10. Martinelli, Nicola: 8 articles (01/2021 - 12/2003)

Related Diseases

1. Hypertriglyceridemia
2. Cardiovascular Diseases (Cardiovascular Disease)
3. Dyslipidemias (Dyslipidemia)
4. Type 2 Diabetes Mellitus (MODY)
5. Infections

Related Drugs and Biologics

1. Triglycerides (Triacylglycerol)
2. Lipoproteins (Lipoprotein)
3. Apolipoproteins E (ApoE)
4. Apolipoprotein C-III
5. Apolipoprotein A-I (Apolipoprotein A1)
6. Proteins (Proteins, Gene)
7. Lipoprotein Lipase (Diacylglycerol Lipase)
8. oxidized low density lipoprotein
9. Small Interfering RNA (siRNA)
10. Lipids

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Glycemic Control
4. Highly Active Antiretroviral Therapy (HAART)
5. Secondary Prevention