Diynes

Compounds with two triple bonds. Some of them are CYTOTOXINS.

Also Known As:

Bisacetylenic Oxylipins; Oxylipins, Bisacetylenic

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Acyclic Hydrocarbons
    - Alkynes: 217
      - Polyynes: 10
        Diynes: 3
        falcarinol: 43
        falcarindiol: 28
        Enediynes: 19
        panaxydol: 18
        cicutoxin: 6
        capillin: 4
        1-chloro-9,10-epoxy-4,6-heptadecadiyne-2,3-diol: 2
        1,2-bis(10,12-tricosadiynoyl)phosphatidylcholine: 1
        indoleacetic acid falcarindiol ester: 1
        (3S,18S,4E,16E)-eicosa-1,19-diyne-3,18-diol-4,16-diene
        (4E,16E)-icosa-4,16-diene-1,19-diyne-3,18-diol
        (6E,12Z)-tetradecadiene-8,10-diyne-1,3-diol
        (E)-9-oxooctadec-10-en-12-ynoic acid
        1,10-heptadecadiene-4,6-diyne-3,8,9-triol
        1,2-bis(15-oxapentacosa-10,12-diynoyl)-sn-phosphocholine
        1,2-bis(9,16-dioxahexacosa-11,13-diynoyl)-sn-3-phosphocholine
        1,6-bis(4,7-diaza-6-methyl-5-oxo-3-((2-((5-(phenylthio)tetrazol-1-yl)methyl)pyrrolidin-1-yl)carbonyl)octyloxy)-2,4-hexadiyne
        1,6-diphenyl-3-hexene-1,5,-diyne
        1,8-heptadecadiene-4,6-diyne-3,10-diol
        1,9,16-heptadecatriene-4,6-diyne-3,8-diol
        1,9-heptadecadiene-4,6-diyne-3,8,11-triol
        1-(2-furyl)pentacosa-16,18-diyne
        10-chloro-1-heptadecene-4,6-diyne-3,8,9-triol
        11-oxooctadeca-9,12-diynoic acid
        13,14-dihydrooropheic acid
        14-iodotetradeca-13-en-3,5-diyn-1-ol
        16-hydroxy-9,17-octadecadiene-12,14-diynoic acid
        2-(4-acetoxy-3-chloro-1-butyn-1-yl)-5-(1,3-butadiyn-1-yl)thiophene
        23-(2-furyl)tricosa-5,7-diynoic acid
        6-diyne-3-one (9R,10S)-epoxy-16-heptadecene-4
        atractylodemayne A
        dodeca-2Z,4E-diene-8,10-diynoic acid isobutylamide
        exocarpic acid
        heneicosa-10,12-diynoic acid
        octadeca-9,12-diynoic acid
        panaxacol
        panaxydiol
        panaxydol chlorohydrin
        santolindiacetylene
        spiroketalenol ether-6,7-epoxy-diyne
        tetradecadiene-8,10-diyne-1,3-diol diacetate
        xerulinic acid

Experts

1.	Gorman, Christopher B: 1 article (05/2011)
2.	Kim, Yun-Ho: 1 article (05/2011)
3.	Lee, Saet Byoul: 1 article (12/2010)
4.	Nho, Chu Won: 1 article (12/2010)
5.	Shin, Dongyun: 1 article (12/2010)
6.	Yang, Jung-Eun: 1 article (12/2010)
7.	David, Wendi M: 1 article (04/2002)
8.	Kerwin, Sean M: 1 article (04/2002)
9.	Kumar, Dalip: 1 article (04/2002)
10.	Salazar, Miguel: 1 article (04/2002)

Related Diseases

1.	Neoplasms (Cancer) 12/15/2010 - "We synthesized diyne triols based on gymnasterkoreayne and evaluated their cancer chemopreventive activities in terms of the chemopreventive index (CI) to reveal the structure-activity relationship, and discovered more active compounds than natural diynes." 04/23/2002 - "DNA modification by 4-aza-3-ene-1,6-diynes: DNA cleavage, pH-dependent cytosine-specific interactions, and cancer cell cytotoxicity."
2.	Skeletal Abnormalities Mandibular Hypoplasia Auditory Canal Atresia Short Stature 05/17/2011 - "The looped SAMs composed of α,ω-diynes offer a less densely packed and thus somewhat accessible surface that may be useful when the underlying surface is used as an electrode. " 05/17/2011 - "It is shown that self-assembled monolayers (SAMs) composed of α,ω-diynes on gold have different structures depending on the concentration of molecules used to make the SAM. "

Related Drugs and Biologics

1.	Gold
2.	DNA (Deoxyribonucleic Acid)
3.	Cytosine

Related Therapies and Procedures

1.	Electrodes (Electrode)