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Myeloblastin (Proteinase 3)

A polymorphonuclear leukocyte-derived serine protease that degrades proteins such as ELASTIN; FIBRONECTIN; LAMININ; VITRONECTIN; and COLLAGEN. It is named for its ability to control myeloid cell growth and differentiation.
Also Known As:
Proteinase 3; Azurophil Granule Protein 7; C-ANCA Antigen; Leukocyte Proteinase 3; Myeloblastin, Human; N-Proteinase 4; Neutrophil Proteinase 3, Human; Neutrophil Proteinase 4; PRTN3 Gene Protein; Antigen, C-ANCA; Autoantigen, Wegener; C ANCA Antigen; Human Myeloblastin; N Proteinase 4; Protein, PRTN3 Gene; Proteinase 3, Leukocyte; Proteinase 3, Neutrophil; Proteinase 4, Neutrophil; Neutrophil Proteinase 3; Wegener Autoantigen
Networked: 807 relevant articles (30 outcomes, 55 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Kallenberg, Cees G M: 26 articles (11/2019 - 01/2002)
2. Specks, Ulrich: 21 articles (01/2020 - 02/2003)
3. Stegeman, Coen A: 20 articles (01/2017 - 01/2002)
4. Merkel, Peter A: 18 articles (01/2022 - 04/2003)
5. Csernok, Elena: 15 articles (05/2019 - 06/2002)
6. Jenne, Dieter E: 15 articles (01/2019 - 09/2004)
7. Witko-Sarsat, Véronique: 15 articles (01/2019 - 12/2007)
8. Falk, Ronald J: 13 articles (01/2022 - 09/2003)
9. Jennette, J Charles: 13 articles (01/2022 - 09/2003)
10. Korkmaz, Brice: 12 articles (01/2020 - 12/2008)

Related Diseases

1. Vasculitis (Vasculitides)
2. Granulomatosis with Polyangiitis (Wegener's Granulomatosis)
3. Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
4. Inflammation (Inflammations)
5. Leukemia

Related Drugs and Biologics

1. Antineutrophil Cytoplasmic Antibodies (ANCA)
2. Peroxidase (Myeloperoxidase)
3. Glucocorticoids
4. Autoantibodies
5. Antibodies
6. Antigens
7. Pancreatic Elastase (Elastase)
8. Leukocyte Elastase (Neutrophil Elastase)
9. Rituximab (Mabthera)
10. Peptide Hydrolases (Proteases)

Related Therapies and Procedures

1. Therapeutics
2. Secondary Prevention
3. Remission Induction
4. Plasma Exchange
5. Aftercare (After-Treatment)