Pyomyositis

An intramuscular suppuration of the large skeletal muscle groups. It is associated with INFECTION such as STAPHYLOCOCCUS AUREUS and PYODERMA. It was known as a tropical disease but is increasing among the immunocompromised (IMMUNOCOMPROMISED HOST). Symptoms include muscle pain, FEVER, and leucocytosis. It has been diagnosed by MRI SCANS.

Also Known As:

Networked: 116 relevant articles (3 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Abscess
2.	Pneumonia (Pneumonitis)
3.	Cellulitis
4.	Furunculosis (Boils)
5.	Chronic Bronchitis

Experts

1.	Yuen, Kwok-Yung: 2 articles (11/2010 - 02/2003)
2.	Chang, Feng-Yee: 2 articles (05/2009 - 08/2008)
3.	Chiu, Sheng-Kang: 2 articles (05/2009 - 08/2008)
4.	Koudela, K: 2 articles (06/2008 - 02/2005)
5.	Markatseli, Theodora E: 1 article (09/2015)
6.	Voulgari, Paraskevi V: 1 article (09/2015)
7.	Drosos, Alexandros A: 1 article (09/2015)
8.	Somarakis, George A: 1 article (09/2015)
9.	Kosta, Paraskevi: 1 article (09/2015)
10.	Matthaiou, Maria: 1 article (09/2015)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Pyomyositis:

1.	Anti-Bacterial Agents (Antibiotics)IBA 01/01/2011 - "We present the first described case of iliopsoas pyomyositis with reversible bilateral hydroureteronephrosis that was treated successfully with intravenous antibiotics, without the necessity of surgical intervention. " 01/01/2011 - "This is the first case report describing iliopsoas pyomyositis with reversible bilateral dilation of the urinary tract that was treated successfully with intravenous antibiotics, without surgical intervention. " 05/01/2009 - "Both adequate antibiotics and surgical intervention are important for the successful treatment of pyomyositis caused by ESBL-producing E. " 12/01/2008 - "We report signs and symptoms of piriformis pyomyositis in 3 women who were treated mainly with antibiotics. " 08/01/2008 - "Patients with primary pyomyositis should be treated with appropriate broad-spectrum antibiotics and be monitored closely for complications. "
2.	Ampicillin (Omnipen)FDA LinkGeneric 01/01/1983 - "The antibiotic was found to be effective in acute lobar pneumonia, pyogenic meningitis, acute and chronic bronchitis, acute pharyngitis, acute tonsillitis, cellulitis, furunculosis, and pyomyositis caused by such ampicillin-sensitive organisms as Neisseria meningitidis, Diplococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, Streptococcus pyogenes, Klebsiella pneumoniae, and Escherichia coli. "
3.	CatalaseIBA 12/01/1992 - "Pyomyositis due to catalase-negative organism in patient with AIDS." 02/01/2003 - "In this study, we report the isolation of a catalase-negative, alpha-hemolytic, optochin- and bacitracin-resistant viridans group strain, which does not grow in 10 or 40% bile, on MacConkey agar or bile esculin agar, or in 6% NaCl, from the blood culture of a 73-year-old woman with pyomyositis and poststreptococcal reactive arthritis. "
4.	Esculin (Aesculin)IBA 02/01/2003 - "In this study, we report the isolation of a catalase-negative, alpha-hemolytic, optochin- and bacitracin-resistant viridans group strain, which does not grow in 10 or 40% bile, on MacConkey agar or bile esculin agar, or in 6% NaCl, from the blood culture of a 73-year-old woman with pyomyositis and poststreptococcal reactive arthritis. "
5.	Bacitracin (Baci-Rx)FDA LinkGeneric 02/01/2003 - "In this study, we report the isolation of a catalase-negative, alpha-hemolytic, optochin- and bacitracin-resistant viridans group strain, which does not grow in 10 or 40% bile, on MacConkey agar or bile esculin agar, or in 6% NaCl, from the blood culture of a 73-year-old woman with pyomyositis and poststreptococcal reactive arthritis. "
6.	AgarIBA 02/01/2003 - "In this study, we report the isolation of a catalase-negative, alpha-hemolytic, optochin- and bacitracin-resistant viridans group strain, which does not grow in 10 or 40% bile, on MacConkey agar or bile esculin agar, or in 6% NaCl, from the blood culture of a 73-year-old woman with pyomyositis and poststreptococcal reactive arthritis. "
7.	ertapenem (Invanz)FDA Link 11/01/2010 - "In this study, a diabetic patient with recurrent pyomyositis and osteomyelitis caused by extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae developed ertapenem resistance after imipenem/cilastatin treatment, which was a currently recommended therapy. "
8.	imipenem drug combination cilastatin (Primaxin)FDA Link 11/01/2010 - "In this study, a diabetic patient with recurrent pyomyositis and osteomyelitis caused by extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae developed ertapenem resistance after imipenem/cilastatin treatment, which was a currently recommended therapy. "
9.	ethylhydrocupreineIBA 02/01/2003 - "In this study, we report the isolation of a catalase-negative, alpha-hemolytic, optochin- and bacitracin-resistant viridans group strain, which does not grow in 10 or 40% bile, on MacConkey agar or bile esculin agar, or in 6% NaCl, from the blood culture of a 73-year-old woman with pyomyositis and poststreptococcal reactive arthritis. "
10.	Penicillins (Penicillin)FDA Link 07/01/1992 - "This case illustrates important aspects of tropical pyomyositis with a discussion of the natural history of this disease as well as diagnostic modalities and treatment options for this virulent infectious process that is usually caused by penicillin-resistant Staphylococcus aureus." 12/01/1946 - "Penicillin in the treatment of tropical pyomyositis." 12/01/1981 - "Even when the possibility of staphylococcal infection is suspected, penicillin or penicillin and chloramphenicol continue to be the initial treatment prescribed in 90.6% of subjects with pyomyositis, 88.5% with acute osteomyelitis, 88.2% with pneumonia and 90% with bacteraemia. " 03/01/2012 - "The diagnosis of diffuse pyomyositis of both psoas muscles was performed with MRI and culture of a posterior paravertebral collection, from which Staphylococcus aureus resistant to oxacillin, penicillin and dicloxacillin was isolated."

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 10/01/2010 - "Pyomyositis is a rare complication of chemotherapy that is commonly seen in tropical climates and in patients with immunodeficiency states. " 07/01/2003 - "Pyomyositis is a rare complication of chemotherapy. " 02/01/2000 - "Pyomyositis is a rare complication of chemotherapy. " 08/01/1996 - "Four cases of pyomyositis occurring in ALL patients shortly after induction chemotherapy have now been described. " 06/01/1994 - "Successful percutaneous drainage of gluteal pyomyositis occurring after intra-arterial chemotherapy and pelvic irradiation."
2.	Transplants (Transplant) 05/01/2000 - "Isolated tuberculous pyomyositis in a renal transplant patient." 04/15/2000 - "[Pyomyositis caused by Nocardia asteroides in a patient with kidney transplant]." 06/01/2008 - "Patients with peripheral vascular disease presenting with pyomyositis may be difficult to distinguish from those with critical ischemia or synthetic graft sepsis. " 01/01/1996 - "Pyomyositis in a renal transplant patient with Kyrle's disease."
3.	Transplantation (Transplant Recipients) 08/01/2012 - "Tuberculous pyomyositis in a renal transplant recipient." 11/01/2007 - "We report a case of pyomyositis due to Mycobacterium haemophilum in a renal transplant recipient. " 11/01/2007 - "Case of pyomyositis due to Mycobacterium haemophilum in a renal transplant recipient." 08/01/1992 - "Tuberculous pyomyositis in a renal transplant recipient." 12/01/1999 - "We describe a renal transplant recipient who presented with tropical myositis and acute allograft dysfunction 2(1/2) years after transplantation. "
4.	Debridement 01/01/2014 - "Pyomyositis requires early debridement and continue cure. " 04/01/2014 - "Clinical algorithms are incapable of differentiating these pathologies suggesting that both be considered under the current diagnosis previously referred to as "presumed septic arthritis." Incorrect diagnosis of a septic arthritis in the presence of a pericapsular pyomyositis could potentially lead to unnecessary debridement of the joint in the presence of extra-articular infection, thus contaminating the joint. " 01/01/2013 - "We present a case of a 45-year-old immunocompetant gentleman with a thigh swelling with sepsis due to pyomyositis of the quadriceps requiring a multimodal management of drainage of abscess, debridement of devitalized muscle, antitubercular drugs, and physiotherapy. " 10/01/2010 - "Clinically relevant findings illustrated in this case include potential development of antibiotic resistance within Fusobacterium genus with little to no response to several surgical debridements and broad-spectrum and targeted antibiotics, and development of multifocal, ipsilateral septic arthritis and soft tissue abscesses and pyomyositis in the context of steroid use and recent intra-articular knee injury."
5.	Intramuscular Injections 01/01/2014 - "Intramuscular injections often cause haematomas that can lead to pyomyositis. " 07/01/2011 - "Simultaneous pyomyositis and hip septic arthritis due to Bacteroides fragilis is rare, but should be considered possible after intramuscular injections." 04/01/2003 - "Pyomyositis or "injectiositis"--Staphylococcus aureus multiple abscesses following intramuscular injections."