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Replication Protein C (Replication Factor C)

A DNA-binding protein and AAA ATPase that consists of 5 polypeptides and plays an essential role in DNA REPLICATION in eukaryotes. It binds DNA PRIMER-template junctions and recruits PROLIFERATING CELL NUCLEAR ANTIGEN and DNA POLYMERASES to the site of DNA synthesis.
Also Known As:
Replication Factor C; Activator 1 Protein; Activator 1 Protein, 145 kDa Subunit; Activator 1 Protein, 36 kDa Subunit; Activator 1 Protein, 37 kDa Subunit; Activator 1 Protein, 38 kDa Subunit; Activator 1 Protein, 40 kDa Subunit; Activator 1 p40; Replication Factor C, Subunit 1; Replication Factor C, Subunit 2; Replication Factor C, Subunit 3; Replication Factor C, Subunit 4; Replication Factor C, Subunit 5; Replication Protein C, Subunit 1; Replication Protein C, Subunit 2; Replication Protein C, Subunit 3; Replication Protein C, Subunit 4; Replication Protein C, Subunit 5
Networked: 56 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Cortese, Andrea: 3 articles (03/2021 - 01/2019)
2. Donaldson, Anne D: 3 articles (11/2018 - 07/2011)
3. Kubota, Takashi: 3 articles (11/2018 - 07/2011)
4. Houlden, Henry: 2 articles (03/2021 - 01/2019)
5. Lockhart, Paul J: 2 articles (11/2020 - 06/2020)
6. Myung, Kyungjae: 2 articles (08/2013 - 04/2010)
7. Kupiec, Martin: 2 articles (04/2005 - 08/2003)
8. Li, Wang-Jun: 1 article (12/2022)
9. Liao, Xiao-Wei: 1 article (12/2022)
10. Wu, Dong-Wei: 1 article (12/2022)

Related Diseases

1. Lung Neoplasms (Lung Cancer)
2. Genomic Instability
3. Neoplasms (Cancer)
4. Cerebellar Ataxia (Dysmetria)
5. Ataxia (Dyssynergia)

Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. Proliferating Cell Nuclear Antigen (PCNA)
3. DNA (Deoxyribonucleic Acid)
4. Chromatin
5. Replication Protein A
6. DNA Primase (Primase)
7. Biomarkers (Surrogate Marker)
8. Transcription Factors (Transcription Factor)
9. Tumor Viral Antigens (Large T Antigen)
10. Minichromosome Maintenance Complex Component 2