Kruppel-Like Transcription Factors (Kruppel-Like Factors)

A family of zinc finger transcription factors that share homology with Kruppel protein, Drosophila. They contain a highly conserved seven amino acid spacer sequence in between their ZINC FINGER MOTIFS.

Also Known As:

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Lin, Shu-Hui: 2 articles (12/2013 - 04/2012)
2.	Chen, Chih-Jung: 2 articles (12/2013 - 04/2012)
3.	Farrugia, M K: 1 article (01/2015)
4.	Ammer, A G: 1 article (01/2015)
5.	Salkeni, M A: 1 article (01/2015)
6.	Vanderbilt, D B: 1 article (01/2015)
7.	Stoilov, P: 1 article (01/2015)
8.	Ruppert, J M: 1 article (01/2015)
9.	Sharma, S B: 1 article (01/2015)
10.	Creighton, C J: 1 article (01/2015)

Related Diseases

1.	Atherosclerosis 06/01/2013 - "Interplay between NF-κB and Kruppel-like factors in vascular inflammation and atherosclerosis: location, location, location." 10/01/2012 - "Kruppel-like factors and vascular inflammation: implications for atherosclerosis."
2.	Inflammation 06/01/2013 - "Interplay between NF-κB and Kruppel-like factors in vascular inflammation and atherosclerosis: location, location, location." 10/01/2012 - "Kruppel-like factors and vascular inflammation: implications for atherosclerosis."
3.	Breast Neoplasms (Breast Cancer) 04/01/2012 - "Kruppel-like factors (KLFs) are import modulators of cell proliferation, differentiation, and transformation and have recently been considered possible prognostic factors in breast cancer. " 01/01/2015 - "Regulation of anti-apoptotic signaling by Kruppel-like factors 4 and 5 mediates lapatinib resistance in breast cancer."
4.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 07/01/2011 - "The known participation of Kruppel-like transcription factors (KLF) in cellular differentiation prompted us to investigate their expression in acute myeloid leukemia (AML) blast cells that are typically blocked in their differentiation. " 07/01/2011 - "Deregulated expression of Kruppel-like factors in acute myeloid leukemia."
5.	Neoplasms (Cancer) 12/01/2013 - "Kruppel-like factors (KLFs) play either anti- or pro-proliferation roles in different human cancers. "

Related Drugs and Biologics

1.	Transcription Factors (Transcription Factor)
2.	Carrier Proteins (Binding Protein)
3.	lapatinib (GW572016)