Sp2 Transcription Factor

A ubiquitously expressed Sp transcription factor that binds to the consensus DNA sequence GGGCGGGAC.

Also Known As:

Specificity Protein 2 Transcription Factor; Transcription Factor, Sp2; Transcription Factor Sp2

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

1.	Carcinogenesis 11/01/2010 - "Overexpression of transcription factor sp2 inhibits epidermal differentiation and increases susceptibility to wound- and carcinogen-induced tumorigenesis."
2.	Wounds and Injuries (Trauma) 11/01/2010 - "Overexpression of transcription factor sp2 inhibits epidermal differentiation and increases susceptibility to wound- and carcinogen-induced tumorigenesis."
3.	Neoplasms (Cancer) 01/01/2022 - "The Sp2 transcription factor and six of the seven genes had previously been associated with cancer onset, progression, and metastasis. "
4.	Neoplasm Metastasis (Metastasis) 01/01/2022 - "The Sp2 transcription factor and six of the seven genes had previously been associated with cancer onset, progression, and metastasis. "
5.	Glioma (Gliomas) 01/01/2021 - "The transcription factor SP2 directly bound to the promoter regions of the VM formation-related proteins MMP2, MMP9, and VE-cadherin, playing a role in promoting transcription in order to regulate the VM formation ability of glioma cells."