Delayed Rectifier Potassium Channels

A group of slow opening and closing voltage-gated potassium channels. Because of their delayed activation kinetics they play an important role in controlling ACTION POTENTIAL duration.

Also Known As:

Networked: 14 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	An, Dong: 1 article (01/2021)
2.	Chen, Lei: 1 article (01/2021)
3.	Du, Yimei: 1 article (01/2021)
4.	Li, Yingchun: 1 article (01/2021)
5.	Men, Chen: 1 article (01/2021)
6.	Sha, Sha: 1 article (01/2021)
7.	Wang, Xiaoli: 1 article (01/2021)
8.	Xu, Weixing: 1 article (01/2021)
9.	Zhou, Li: 1 article (01/2021)
10.	Bébarová, Markéta: 1 article (01/2019)

Related Diseases

1.	Cardiac Arrhythmias (Arrythmia) 04/30/1999 - "Dysfunction of delayed rectifier potassium channels in an inherited cardiac arrhythmia." 01/18/2008 - "Inhibition of delayed rectifier potassium channels and induction of arrhythmia: a novel effect of celecoxib and the mechanism underlying it." 01/01/2011 - "So far, delayed rectifier potassium channels have been linked to human deafness associated with prolongation of the QT interval on electrocardiograms and ventricular arrhythmia in Jervell and Lange-Nielsen syndrome. " 06/24/2011 - "Since 1995, when a potassium channel gene, hERG (human ether-à-go-go-related gene), now referred to as KCNH2, encoding the rapid component of cardiac delayed rectifier potassium channels was identified as being responsible for type 2 congenital long-QT syndrome, a number of potassium channel genes have been shown to cause different types of inherited cardiac arrhythmia syndromes. "
2.	Long QT Syndrome 02/01/2001 - "Numerous mutations in KCNQ1, a gene encoding the alpha -subunit of cardiac delayed rectifier potassium channels, have been found in long QT syndrome (LQTS). " 01/01/2019 - "Impaired Adrenergic/Protein Kinase A Response of Slow Delayed Rectifier Potassium Channels as a Long QT Syndrome Motif: Importance and Unknowns." 06/24/2011 - "Since 1995, when a potassium channel gene, hERG (human ether-à-go-go-related gene), now referred to as KCNH2, encoding the rapid component of cardiac delayed rectifier potassium channels was identified as being responsible for type 2 congenital long-QT syndrome, a number of potassium channel genes have been shown to cause different types of inherited cardiac arrhythmia syndromes. "
3.	Channelopathies 04/01/2014 - "Several channelopathies, both soma-dendritic (L-type calcium channels, Slack potassium channels, h-channels, A-type potassium channels) and axo-somatic (BK channels and delayed rectifier potassium channels) were identified in the fmr1-/y mouse model of fragile X syndrome. "
4.	Jervell-Lange Nielsen Syndrome (Jervell and Lange-Nielsen Syndrome) 01/01/2011 - "So far, delayed rectifier potassium channels have been linked to human deafness associated with prolongation of the QT interval on electrocardiograms and ventricular arrhythmia in Jervell and Lange-Nielsen syndrome. "
5.	Tinnitus 11/01/2005 - "To understand what role of the transient outward potassium channels and the delayed rectifier potassium channels play in the mechanism of salicylate-induced tinnitus. "

Related Drugs and Biologics

1.	Potassium Channels (Potassium Channel)
2.	Large-Conductance Calcium-Activated Potassium Channels (Maxi-K Channels)
3.	L-Type Calcium Channels (Dihydropyridine Receptor)
4.	Adrenergic Agents (Adrenergic Drugs)
5.	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)
6.	4-Aminopyridine (4 Aminopyridine)
7.	Salicylates
8.	Messenger RNA (mRNA)
9.	Pilocarpine (Ocusert)
10.	Ether (Diethyl Ether)