A DNA-binding protein that contains an N-terminal BTB (POZ) DOMAIN and C-terminal CYS2-HIS2 ZINC FINGERS. It represses GENETIC TRANSCRIPTION of target genes by recruiting HISTONE DEACETYLASES. Aberrant Blc-6 expression is associated with certain types of human B-CELL LYMPHOMA.
Also Known As:
B-Cell Lymphoma 6 Protein; Proto-Oncogene Protein bcl-6; Proto-Oncogene Protein c-bcl-6; Zinc Finger Protein 51; B Cell Lymphoma 6 Protein; Proto Oncogene Protein bcl 6; Proto Oncogene Protein c bcl 6; Proto Oncogene Proteins c bcl 6; Proto-Oncogene Proteins, bcl-6; Proto-Oncogene Proteins, c-bcl-6; bcl 6 Proto Oncogene Proteins; bcl-6, Proto-Oncogene Protein; c bcl 6 Protein; c bcl 6 Proto Oncogene Proteins; c-bcl-6, Proto-Oncogene Proteins; bcl-6 Proto-Oncogene Proteins; c-bcl-6 Protein; c-bcl-6 Proto-Oncogene Proteins