Fibroblast Growth Factor 7

10/01/2010 - "A significant reduction in the incidence of radiation-induced oral mucositis by Palifermin has been demonstrated. "
10/01/2014 - "Assessment of the hamster cheek pouch as a model for radiation-induced oral mucositis, and evaluation of the protective effects of keratinocyte growth factor using this model."
10/01/2014 - "Additionally, palifermin when administered on days 1, 2 and 3 after irradiation (40 Gy) reduced the severity of oral mucositis. "
01/01/2008 - "Few data are available on the efficacy of and tolerance to palifermin in the preventive treatment of oral mucositis in autograft patients treated with conditioning protocols usually used in France. "
08/01/2007 - "The efficacy of palifermin during less aggressive regimens, which cause less severe oral mucositis, is not known. "

12/01/2011 - "Furthermore, we additionally amended supportive care with palifermin as it reduced severity and prevalence of mucositis [5]."
09/01/2011 - "Further studies are indicated to investigate the prophylactic potential of palifermin against intestinal mucositis."
05/20/2008 - "Future studies should evaluate higher palifermin doses with longer and more standardized assessment of acute mucositis."
08/01/2002 - "Cell kinetic studies in the murine ventral tongue epithelium: mucositis induced by radiation and its protection by pretreatment with keratinocyte growth factor (KGF)."
04/01/1999 - "Mucositis could be influenced by new keratinocyte growth factor (KGF), which is now in phase I trials."

10/27/2001 - "Keratinocyte growth factor (KGF) ameliorates graft-versus-host disease (GVHD)-associated organ injury in murine BMT models. "
12/15/2000 - "Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury."
01/01/2012 - "Recombinant human KGF, also known as palifermin, protects epithelial cells from injury induced by chemicals, irradiation and acute murine graft-versus-host disease (GVHD). "
10/01/2011 - "However, additional data on the long-term safety of palifermin and its potential influence on graft versus host disease (GvHD) are needed. "
06/01/2011 - "Using the C57BL/6→(C57BL/6 x DBA/2)F(1)-hybrid model of acute graft-versus-host disease (GVHD), we previously showed that treating the donor mice with palifermin provides protection from morbidity and a shift from Th1 to Th2 cytokine production. "

12/01/1999 - "Keratinocyte growth factor (KGF) stimulates gastrointestinal epithelial cells in vivo, and is protective against gastrointestinal injury and colitis. "
04/01/1996 - "Keratinocyte growth factor ameliorates mucosal injury in an experimental model of colitis in rats."
07/01/1998 - "Systemic application of keratinocyte growth factor (KGF) has been shown to promote mucosal healing in models of colitis in rats and mice. "
04/01/1999 - "Keratinocyte growth factor ameliorates dextran sodium sulfate colitis in mice."
03/15/1999 - "Other growth factors such as insulin - like growth factor, keratinocyte growth factor, hepatocyte growth factor and trefoil peptides have been implicated in gastrointestinal (gastric ulcers, colitis) regeneration following injury. "

12/01/2004 - "In addition, when keratinocyte growth factor (KGF), a growth factor that has been shown to improve wound healing, was added to wounds during 3 d, the re-epithelialization was significantly accelerated. "
12/01/1999 - "In this study, we investigated the stimulation of epithelial wound closure by keratinocyte growth factor (KGF) in vitro and the mechanisms by which KGF overcomes the inhibition due to mechanical strain. "
06/01/1998 - "Keratinocyte growth factor on trial for wound repair."
01/01/2014 - "Keratinocyte growth factor 1 (KGF1) is a growth factor that promotes epidermal cell proliferation, migration, differentiation, and wound repair. "
05/01/2013 - "This multi-functional material was tested for its influence on wound healing: scaffolds were loaded with plasmids encoding keratinocyte growth factor (KGF) and applied to full-thickness wounds in mice. "