A fibroblast growth factor receptor which contains three extracellular IMMUNOGLOBULIN I-SET DOMAINS and is expressed as two isoforms. One receptor isoform is expressed in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform is expressed mainly by EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME).
Also Known As:
Fibroblast Growth Factor Receptor 2; Receptor, Fibroblast Growth Factor, Type 2; BEK Fibroblast Growth Factor Receptor; BEK Fibroblast Growth Factor Receptor Kinase; BEK Protein Tyrosine Kinase; Bek Fgf Receptor Kinase; Bek-Related Fibroblast Growth Factor-Receptor-1; CD332 Antigen; FGFR2 Protein; FGFR2b; FGFR2c; Fibroblast Growth Factor Receptor 2b; Fibroblast Growth Factor Receptor 2c; Fibroblast Growth Factor Receptors 2; Fibroblast Growth Factor Receptors 2b; Receptor, Fibroblast Growth Factor 2b; Receptor, Fibroblast Growth Factor 2c; Antigen, CD332; Bek Related Fibroblast Growth Factor Receptor 1