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Aquaporin 3

Aquaporin 3 is an aquaglyceroporin that is expressed in the KIDNEY COLLECTING DUCTS and is constitutively localized at the basolateral MEMBRANE.
Also Known As:
AQP3 Protein; Aquaporin 3 Protein
Networked: 112 relevant articles (2 outcomes, 12 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Shen, Lizong: 7 articles (01/2018 - 01/2012)
2. Wang, Yao: 5 articles (01/2018 - 08/2015)
3. Wang, Shoulin: 4 articles (01/2018 - 08/2015)
4. Wen, Jianfei: 4 articles (01/2018 - 11/2015)
5. Zhang, Weiming: 4 articles (01/2018 - 01/2012)
6. Otto, Wolfgang: 4 articles (01/2017 - 03/2012)
7. Zhou, Yangchun: 4 articles (03/2016 - 08/2015)
8. Zhang, Zhihong: 3 articles (01/2018 - 11/2015)
9. Burger, Maximilian: 3 articles (01/2017 - 10/2012)
10. Hartmann, Arndt: 3 articles (01/2017 - 10/2012)

Related Diseases

1. Oligohydramnios
2. Diarrhea
10/06/2020 - "As an important carrier for intestinal secretion and water absorption, aquaporin 3 (AQP3) is closely related to diarrhea. "
01/01/2018 - "Recent investigations have shown that tight junction (TJ) proteins and aquaporin 3 (AQP 3) are contributing factors in bacterial diarrhea. "
05/23/2021 - "The 15 chemical substances of the highest concentration in AO were identified using GC-MS. AO was effective against IBS-D in the rat model, in terms of increased body weight, diarrhea grade score, levels of interleukin-10 (IL-10), aquaporin 3 (AQP3), and aquaporin 8 (AQP8), and reduced fecal moisture content, levels of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), 5-HT, VIP, and SP, while also reducing intestinal injury, as observed using hematoxylin-eosin (HE) staining. "
04/11/2023 - "In addition, mono-lactate glyceride supplementation could enhance intestinal mucosal growth by increasing (p < 0.05) the mRNA levels of extracellular regulated protein kinases, promote intestinal mucosal water and nutrient transport and lipid metabolism by increasing (p < 0.05) the mRNA levels of b0,+ amino acid transporter, aquaporin 3, aquaporin 10, gap junction protein alpha 1, intestinal fatty acid-binding protein, and lipoprotein lipase, enhance antiviral and immune function by increasing (p < 0.05) the mRNA levels of nuclear factor kappa-B, interferon-β, mucovirus resistance protein II, 2'-5'-oligoadenylate synthetase-like, interferon-γ, C-C motif chemokine ligand 2, and toll-like receptor 4, and enhance antioxidant capacity by increasing (p < 0.05) the mRNA levels of NF-E2-related factor 2 and glutathione S-transferase omega 2 and decreasing (p < 0.05) the mRNA level of NADPH oxidase 2. These results suggested that dietary supplementation with mono-lactate glyceride could decrease the diarrhea rate by improving intestinal antioxidant capacity, intestinal mucosal barrier, intestinal immune defense function, and intestinal mucosal water and nutrient transport. "
3. Body Weight (Weight, Body)
4. Neoplasms (Cancer)
5. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
2. Interleukin-10 (Interleukin 10)
3. Interleukin-6 (Interleukin 6)
4. Serotonin (5 Hydroxytryptamine)
5. Hematoxylin (Haematoxylon)
6. Eosine Yellowish-(YS) (Eosin)
7. aquaporin 8
8. Aquaporins (Water Channels)
9. Aquaporin 1
10. Small Interfering RNA (siRNA)

Related Therapies and Procedures

1. Cryotherapy (Therapy, Cold)
2. Therapeutics
3. Moxibustion
4. Ligation
5. Drug Therapy (Chemotherapy)