Destrin (Actin Depolymerizing Factor)

10/06/2016 - "Intranasal immunization with recombinant Toxoplasma gondii actin depolymerizing factor confers protective efficacy against toxoplasmosis in mice."
03/01/2012 - "In the present study, we evaluated the protective efficacy of a recombinant actin depolymerizing factor (ADF) subunit vaccine against Toxoplasma gondii infection in BALB/c mice. "
03/01/2012 - "Toxoplasma gondii: protective immunity against toxoplasmosis with recombinant actin depolymerizing factor protein in BALB/c mice."

01/01/2017 - "This study reported that LIMK1 and destrin were highly expressed in colon cancer and associated with poor prognosis of patients with colon cancer. "
11/15/2007 - "Taken together, our results suggest that destrin is a significant regulator of various processes important for invasive phenotype of human colon cancer Isreco1 cells whereas cofilin-1 may be involved in only a subset of them."
11/15/2007 - "In addition, the putative function of destrin (also known as ADF) had not been explored in this context despite the fact that it is expressed in all colon cancer cell lines examined. "
11/15/2007 - "Differential involvement of destrin and cofilin-1 in the control of invasive properties of Isreco1 human colon cancer cells."
11/15/2007 - "We were therefore prompted to evaluate the respective contributions of these proteins to the invasive properties of the human colon cancer Isreco1 cell line, which expresses a comparatively high destrin/cofilin ratio. "

11/01/2010 - "A study of the expression and interaction of Destrin, cofilin, and LIMK in Debakey I type thoracic aortic dissection tissue."

01/01/2022 - "mitis actin depolymerizing factor to enhance immunoprotections in chicken against the infections of E. "
03/13/2020 - "Actin Depolymerizing Factor Modulates Rhizobial Infection and Nodule Organogenesis in Common Bean."
01/01/2016 - "The Infection of Cucumber (Cucumis sativus L.) Roots by Meloidogyne incognita Alters the Expression of Actin-Depolymerizing Factor (ADF) Genes, Particularly in Association with Giant Cell Formation."
08/01/2012 - "The active form of the actin-depolymerizing factor cofilin 1 was found to increase at an early stage of infection and then to continuously decrease in a manner that corresponded to the remodeling pattern of F-actin, suggesting that cofilin 1 may be involved in the biphasic F-actin dynamics induced by HSV-1 infection. "
10/01/2006 - "Phospholipase D plays an important role in FcgammaRI and C-reactive protein-mediated phagocytosis and phosphorylated cofilin, a ADF (actin depolymerizing factor) is able to bind to phospholipase D and stimulate it; meanwhile, the Listeria-induced actin cytoskeleton rearrangement during the infection is controlled by the phosphorylation of cofilin. "

01/01/1999 - "Ischemia activates actin depolymerizing factor: role in proximal tubule microvillar actin alterations."
05/01/2001 - "Our laboratory previously demonstrated that ischemia-induced cell injury resulted in dephosphorylation and activation of the actin-binding protein, actin depolymerizing factor [(ADF); Schwartz, N, Hosford M, Sandoval RM, Wagner MC, Atkinson SJ, Bamburg J, and Molitoris BA. "
07/01/1999 - "This evidence strongly supports the hypothesis that actin depolymerizing factor/cofilin proteins play a significant role in ischemia-induced injury in the proximal tubule cells."
01/01/2014 - "The actin-depolymerizing factor (ADF)/cofilin protein family has been reported to be associated with ischemia-induced renal disorders. "