Glucose Transporter Type 5

A hexose transporter that mediates FRUCTOSE transport in SKELETAL MUSCLE and ADIPOCYTES and is responsible for luminal uptake of dietary fructose in the SMALL INTESTINE.

Also Known As:

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Bouvet, Vincent: 2 articles (01/2018 - 01/2018)
2.	Glubrecht, Darryl: 2 articles (01/2018 - 01/2018)
3.	Hamann, Ingrit: 2 articles (01/2018 - 01/2018)
4.	Krys, Daniel: 2 articles (01/2018 - 01/2018)
5.	Marshall, Alison: 2 articles (01/2018 - 01/2018)
6.	Wuest, Frank: 2 articles (01/2018 - 01/2018)
7.	Wuest, Melinda: 2 articles (01/2018 - 01/2018)
8.	Camargo, Simone Mafalda Rodrigues: 1 article (11/2019)
9.	Holland-Cunz, Stefan Gerhard: 1 article (11/2019)
10.	Hunziker, Schirin: 1 article (11/2019)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2018 - "GLUT5 protein levels were higher in tumor versus muscle tissue as determined by Western blot and immunohistochemistry. " 01/01/2019 - "GLUT5 (Glucose transporter type 5), as a specific fructose transporter in mammalian cells, has also been found highly expressed in many cancers. " 01/01/2018 - "With GLUT5 staining lower than GLUT1, 6-[18F]FDF revealed lower uptake than [18F]FDG [standardized uptake value (SUV)6-[18F]FDF, 120 min 0.77 ± 0.06 vs. SUV[18F]FDG, 120 min 1.08 ± 0.07] in MDA-MB231 tumors and was blocked by 20% with cytochalasin B after 10 min. Whereas correspondence between 6-[18F]FDF uptake and GLUT5 protein was low, high GLUT2 levels were detected in all cell lines and tumor models. " 01/01/2018 - "Our data suggest that tumor uptake of fructose metabolism-targeting radiotracers 1-[18F]FDF, 6-[18F]FDF, and 1-[18F]FDAM does not correlate with GLUT5 mRNA levels but is linked to GLUT5 protein levels. "
2.	Non-alcoholic Fatty Liver Disease 10/05/2023 - "Individuals with NAFLD exhibited increased duodenal GLUT-5 protein levels in comparison to those without NAFLD, independently of demographic and anthropometric confounders. "
3.	Overweight 01/01/2023 - "SGLT-1, GLUT-2, and GLUT-5 protein levels were assessed on duodenal mucosa biopsies of 52 individuals without diabetes categorized on the basis of their BMI as lean, with overweight, or with obesity. "
4.	Obesity 01/01/2023 - "SGLT-1, GLUT-2, and GLUT-5 protein levels were assessed on duodenal mucosa biopsies of 52 individuals without diabetes categorized on the basis of their BMI as lean, with overweight, or with obesity. "
5.	Intestinal Atresia 11/01/2019 - "Human newborns lack small intestinal fructose transporter GLUT5 protein expression and small intestinal atresia does not affect the expression of hexose transporters."

Related Drugs and Biologics

1.	Fructose
2.	Leptin
3.	Messenger RNA (mRNA)
4.	Proteins (Proteins, Gene)
5.	Insulin (Novolin)
6.	Hexoses
7.	Cytochalasin B
8.	Chlorides
9.	villin