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Secondary Headache Disorders

Subscribe to New Research on Secondary Headache Disorders

Conditions with HEADACHE symptom that can be attributed to a variety of causes including BRAIN VASCULAR DISORDERS; WOUNDS AND INJURIES; INFECTION; drug use or its withdrawal.

Also Known As:

Headache Disorders, Secondary; Analgesic Rebound Headache; Analgesic Overuse Headaches; Analgesic Rebound Headaches; Disorder, Secondary Headache; Disorders, Secondary Headache; Headache Disorder, Secondary; Headache, Analgesic Overuse; Headache, Analgesic Rebound; Headaches, Analgesic Overuse; Headaches, Analgesic Rebound; Secondary Headache Disorder; Analgesic Overuse Headache

Networked: 14 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Disease Context: Research Results

Nervous System Diseases: 6158
- Central Nervous System Diseases: 1649
  - Brain Diseases: 2114
    - Headache Disorders: 626
      - Secondary Headache Disorders: 14
        Post-Dural Puncture Headache: 437
        Vascular Headaches: 150
        Post-Traumatic Headache: 135

Related Diseases

1.	Headache (Headaches)
2.	Headache Disorders (Headache Syndromes)
3.	Tension-Type Headache (Tension Headache)
4.	Pain (Aches)
5.	Migraine Disorders (Migraine)

Experts

1.	Jones, Jeremy C: 1 article (02/2014)
2.	Ross, Edgar L: 1 article (02/2014)
3.	Hassanzadeh, Roya: 1 article (02/2014)
4.	Fiorillo, M: 1 article (12/2011)
5.	Rocchietti-March, M: 1 article (12/2011)
6.	Negro, A: 1 article (12/2011)
7.	Martelletti, P: 1 article (12/2011)
8.	Shapiro, Robert E: 1 article (08/2008)
9.	Sahin, Sevki: 1 article (04/2008)
10.	Savrun, Feray Karaali: 1 article (04/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Secondary Headache Disorders:

1.	Analgesics (Analgesic Drugs)IBA 01/01/1996 - "Frequent, excessive use of over-the-counter or prescription analgesics may lead to analgesic rebound headache. " 11/01/1993 - "Overuse of analgesics is usually a part of this clinical picture, which has been termed "analgesic rebound headache." Fifty-three of the first 100 patients admitted to a community hospital's inpatient headache treatment program had chronic daily headaches and were overusing analgesics or other headache relief medications. " 09/01/1998 - "Discontinuing daily analgesics, with the concomitant use of amitriptyline, is an effective treatment for analgesic rebound headache in this population." 04/01/2002 - "In the United States analgesic-overuse headache is often caused by butalbital-containing analgesics. " 12/01/2011 - "Misuse of ergots, triptans, opioids or combination analgesics on > or = 10 days/month was required to make the diagnosis of MOH, while > or = 15 days/month were needed for simple analgesic-overuse headache. "
2.	Amitriptyline (Elavil)FDA LinkGeneric 09/01/1998 - "Discontinuing daily analgesics, with the concomitant use of amitriptyline, is an effective treatment for analgesic rebound headache in this population."
3.	Ergotamine (Ergotamine Tartrate)FDA LinkGeneric 04/01/2008 - "Twenty-three female patients with probable ergotamine- overuse headache (PEOH), 23 female patients with probable analgesic-overuse headache (PAOH), and 15 healthy female controls participated in the study. " 05/01/2006 - "We found a significant decrease in the relative frequency of probable ergotamine overuse headache (from 18.6% to 0%, P < .0001), and in probable combination analgesic overuse headache (from 42.2% to 13.6%, P < .0001). " 12/01/2003 - "In 80% of patients codeine was the predominant agent implicated in the analgesic rebound headaches (mean 1053 mg/week) and 24% used ergotamine-containing medications (mean 16 mg/week). "
4.	Glutamic Acid (Glutamate)FDA Link 04/01/2003 - "The present study supports the above pathogenic mechanisms demonstrating a significant increase in glutamate and nitrite levels in the CSF of CDH patients, without a significant difference between patients without and those with analgesic overuse headache (P < 0.0001 and P < 0.002). "
5.	Neurotransmitter Agents (Neurotransmitter)IBA 02/01/2014 - "Over the last two decades, implantable electrical neuromodulators, previously established to manage other forms of chronic pain, have been used increasingly for intractable primary and secondary headache disorders. "
6.	Tryptamines (Triptans)IBA 12/01/2011 - "Misuse of ergots, triptans, opioids or combination analgesics on > or = 10 days/month was required to make the diagnosis of MOH, while > or = 15 days/month were needed for simple analgesic-overuse headache. "
7.	Codeine (Codeine Phosphate)FDA LinkGeneric 12/01/2003 - "In 80% of patients codeine was the predominant agent implicated in the analgesic rebound headaches (mean 1053 mg/week) and 24% used ergotamine-containing medications (mean 16 mg/week). "
8.	Carbon MonoxideIBA 02/01/1994 - "These parameters were further evaluated with respect to a variety of subgroups: 1) migraine alone 2) migraine with co-existent tension-type headache 3) drug-induced headache (analgesic rebound headache) 4) posttraumatic headache 5) preventive versus no preventive medication 6) presence or absence of adverse events 7) presence or absence of recurrence and 8) average duration of migraine with no medication."
9.	Caffeine (No Doz)FDA LinkGeneric 08/01/2008 - "Chronic repetitive exposures to caffeine increase the risks for development of analgesic-overuse headache, chronic daily headache, and physical dependency. "
10.	Opioid Analgesics (Opioids)IBA 12/01/2011 - "Misuse of ergots, triptans, opioids or combination analgesics on > or = 10 days/month was required to make the diagnosis of MOH, while > or = 15 days/month were needed for simple analgesic-overuse headache. "

Therapies and Procedures

1.	Drug Therapy (Chemotherapy) 01/01/1996 - "A variety of therapeutic strategies, including pharmacotherapy, were used in the management of analgesic rebound headache. "