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NF-E2-Related Factor 1
A basic-leucine zipper transcription factor that is involved in regulating inflammatory responses, MORPHOGENESIS, and HEME biosynthesis.
Also Known As:
NRF-1 Protein; Nfe2l1 Protein; Nuclear Factor (Erythroid-Derived 2)-Like 1 Protein; NF E2 Related Factor 1; NRF 1 Protein
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Proteins: 484843
Transcription Factors: 38804
Basic-Leucine Zipper Transcription Factors: 187
NF-E2-Related Factor 1: 1
human NFE2L1 protein
mouse Nfe2L1 protein
rat Nfe2l1 protein
DNA-Binding Proteins: 2009
Basic-Leucine Zipper Transcription Factors: 187
NF-E2-Related Factor 1: 1
human NFE2L1 protein
mouse Nfe2L1 protein
rat Nfe2l1 protein
Experts
1.
Babiker, Abdelwahid
: 1 article (11/2008)
2.
Carraway, Martha Sue
: 1 article (11/2008)
3.
Piantadosi, Claude A
: 1 article (11/2008)
4.
Suliman, Hagir B
: 1 article (11/2008)
Related Diseases
1.
Necrosis
11/21/2008 - "
The ensuing accumulation of nuclear NRF-1 protein leads to gene activation for mitochondrial biogenesis, which opposes apoptosis and necrosis caused by the cardio-toxic anthracycline chemotherapeutic agent, doxorubicin.
"
Related Drugs and Biologics
1.
Anthracyclines
2.
Doxorubicin (Adriamycin)