Proto-Oncogene Proteins c-akt (Protein Kinase B)

A protein-serine-threonine kinase that is activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. It plays a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells.
Also Known As:
Protein Kinase B; AKT1 Protein Kinase; AKT2 Protein Kinase; AKT3 Protein Kinase; Akt-alpha Protein; Akt-beta Protein; Akt-gamma Protein; Protein Kinase B alpha; Protein Kinase B beta; Protein Kinase B gamma; Protein-Serine-Threonine Kinase (Rac); Proto-Oncogene Protein Akt; Proto-Oncogene Protein RAC; Proto-Oncogene Proteins c-akt1; Proto-Oncogene Proteins c-akt2; Proto-Oncogene Proteins c-akt3; RAC-PK Protein; Rac Protein Kinase; Rac-PK alpha Protein; Rac-PK beta Protein; Related to A and C-Protein; c-akt Proto-Oncogene Protein; Akt alpha Protein; Akt beta Protein; Akt gamma Protein; Akt, Proto-Oncogene Protein; Protein, akt Proto-Oncogene; Protein, c-akt Proto-Oncogene; Proteins c-akt1, Proto-Oncogene; Proteins c-akt2, Proto-Oncogene; Proteins c-akt3, Proto-Oncogene; Proto Oncogene Protein Akt; Proto Oncogene Protein RAC; Proto Oncogene Proteins c akt; Proto Oncogene Proteins c akt1; Proto Oncogene Proteins c akt2; Proto Oncogene Proteins c akt3; Proto-Oncogene Protein, akt; Proto-Oncogene Protein, c-akt; RAC PK Protein; RAC, Proto-Oncogene Protein; Rac PK alpha Protein; Rac PK beta Protein; Related to A and C Protein; akt Proto Oncogene Protein; alpha Protein, Rac-PK; c akt Proto Oncogene Protein; c-akt, Proto-Oncogene Proteins; c-akt1, Proto-Oncogene Proteins; c-akt2, Proto-Oncogene Proteins; c-akt3, Proto-Oncogene Proteins; akt Proto-Oncogene Protein; c-akt Protein
Networked: 945 relevant articles (23 outcomes, 62 trials/studies)

Relationship Network

Bio-Agent Context: Research Results


1. Maiese, Kenneth: 10 articles (12/2014 - 04/2004)
2. Chong, Zhao Zhong: 8 articles (12/2012 - 04/2004)
3. Zhang, Jing: 6 articles (09/2015 - 04/2008)
4. Xia, Chun: 6 articles (08/2015 - 01/2009)
5. Zhang, Bing: 6 articles (08/2015 - 01/2009)
6. Dong, Qihan: 5 articles (01/2015 - 03/2009)
7. Zhu, Gui-Dong: 5 articles (06/2007 - 09/2002)
8. Li, Qun: 5 articles (06/2007 - 09/2002)
9. Flaherty, Keith T: 4 articles (09/2015 - 08/2010)
10. Yao, Mu: 4 articles (01/2015 - 04/2010)

Related Diseases

1. Reperfusion Injury
2. Melanoma (Melanoma, Malignant)
3. Neoplasms (Cancer)
4. Myocardial Ischemia (Ischemic Heart Diseases)
5. Insulin Resistance

Related Drugs and Biologics

1. Phosphotransferases (Kinase)
2. Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
3. Protein Kinases (Protein Kinase)
4. Sirolimus (Rapamycin)
5. Serine (L-Serine)
6. Insulin (Novolin)
7. Proteins (Proteins, Gene)
8. Phosphatidylinositol 3-Kinases
9. Threonine (L-Threonine)
10. Insulin Receptor

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)
3. Ligation
4. Ischemic Postconditioning
5. Angioplasty (Angioplasty, Transluminal)